Tyrosine Kinase Activity and Transformation Potency of bcr-abl Oncogene Products TG Lugo, AM Pendergast, AJ Muller, ON Witte Science 247 (4946), 1079-1082, 1990 | 1774 | 1990 |
Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow WS Pear, JP Miller, L Xu, JC Pui, B Soffer, RC Quackenbush, ... Blood, The Journal of the American Society of Hematology 92 (10), 3780-3792, 1998 | 955 | 1998 |
BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein AM Pendergast, LA Quilliam, LD Cripe, CH Bassing, Z Dai, N Li, A Batzer, ... Cell 75 (1), 175-185, 1993 | 905 | 1993 |
Role of ABL family kinases in cancer: from leukaemia to solid tumours EK Greuber, P Smith-Pearson, J Wang, AM Pendergast Nature Reviews Cancer 13 (8), 559-571, 2013 | 548 | 2013 |
c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF R Plattner, L Kadlec, KA DeMali, A Kazlauskas, AM Pendergast Genes & development 13 (18), 2400-2411, 1999 | 545 | 1999 |
A requirement for NF-κB activation in Bcr–Abl-mediated transformation JY Reuther, GW Reuther, D Cortez, AM Pendergast, AS Baldwin Genes & development 12 (7), 968-981, 1998 | 524 | 1998 |
BCR First Exon Sequences Specifically Activate the BCR/ABL Tyrosine Kinase Oncogene of Philadelphia ChromosomePositive Human Leukemias AJ Muller, JC Young, AM Pendergast, M Pondel, NR Landau, DR Littman, ... Molecular and cellular biology 11 (4), 1785-1792, 1991 | 512 | 1991 |
BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner AM Pendergast, AJ Muller, MH Havlik, Y Maru, ON Witte Cell 66 (1), 161-171, 1991 | 506 | 1991 |
Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis D Cortez, L Kadlec, AM Pendergast Molecular and cellular biology 15 (10), 5531-5541, 1995 | 402 | 1995 |
The Abl family kinases: mechanisms of regulation and signaling AM Pendergast Academic Press 85, 51-100, 2002 | 373 | 2002 |
Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity. Z Dai, AM Pendergast Genes & development 9 (21), 2569-2582, 1995 | 360 | 1995 |
Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 family GW Reuther, H Fu, LD Cripe, RJ Collier, AM Pendergast Science 266 (5182), 129-133, 1994 | 318 | 1994 |
Expression of a Distinctive BCR-ABL Oncogene in Ph1-Positive Acute Lymphocytic Leukemia (ALL) SS Clark, J McLaughlin, M Timmons, AM Pendergast, Y Ben-Neriah, ... Science 239 (4841), 775-777, 1988 | 304 | 1988 |
The Bcr-Abl tyrosine kinase activates mitogenic signaling pathways and stimulates G1-to-S phase transition in hematopoietic cells D Cortez, G Reuther, AM Pendergast Oncogene 15 (19), 2333-2342, 1997 | 295 | 1997 |
Bcr–Abl variants: biological and clinical aspects AS Advani, AM Pendergast Leukemia research 26 (8), 713-720, 2002 | 244 | 2002 |
The BCR-ABL tyrosine kinase inhibits apoptosis by activating a Ras-dependent signaling pathway. D Cortez, G Stoica, JH Pierce, AM Pendergast Oncogene 13 (12), 2589-2594, 1996 | 206 | 1996 |
SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence AM Pendergast, ML Gishizky, MH Havlik, ON Witte Molecular and cellular biology 13 (3), 1728-1736, 1993 | 204 | 1993 |
Evidence for regulation of the human ABL tyrosine kinase by a cellular inhibitor. AM Pendergast, AJ Muller, MH Havlik, R Clark, F McCormick, ON Witte Proceedings of the National Academy of Sciences 88 (13), 5927-5931, 1991 | 200 | 1991 |
Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction AJ Finn, G Feng, AM Pendergast Nature neuroscience 6 (7), 717-723, 2003 | 185 | 2003 |
A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-γ1 R Plattner, BJ Irvin, S Guo, K Blackburn, A Kazlauskas, RT Abraham, ... Nature cell biology 5 (4), 309-319, 2003 | 183 | 2003 |