Optimal and consistent protein glycosylation in mammalian cell culture P Hossler, SF Khattak, ZJ Li Glycobiology 19 (9), 936-949, 2009 | 843 | 2009 |
Real time monitoring of multiple parameters in mammalian cell culture bioreactors using an in‐line Raman spectroscopy probe NR Abu‐Absi, BM Kenty, ME Cuellar, MC Borys, S Sakhamuri, ... Biotechnology and bioengineering 108 (5), 1215-1221, 2011 | 321 | 2011 |
Scale‐up analysis for a CHO cell culture process in large‐scale bioreactors Z Xing, BM Kenty, ZJ Li, SS Lee Biotechnology and bioengineering 103 (4), 733-746, 2009 | 256 | 2009 |
Technology outlook for real‐time quality attribute and process parameter monitoring in biopharmaceutical development—A review DP Wasalathanthri, MS Rehmann, Y Song, Y Gu, L Mi, C Shao, ... Biotechnology and Bioengineering 117 (10), 3182-3198, 2020 | 117 | 2020 |
Fungal morphology and fragmentation behavior in a fed‐batch Aspergillus oryzae fermentation at the production scale ZJ Li, V Shukla, AP Fordyce, AG Pedersen, KS Wenger, MR Marten Biotechnology and Bioengineering 70 (3), 300-312, 2000 | 116 | 2000 |
Optimizing amino acid composition of CHO cell culture media for a fusion protein production Z Xing, B Kenty, I Koyrakh, M Borys, SH Pan, ZJ Li Process Biochemistry 46 (7), 1423-1429, 2011 | 115 | 2011 |
Development of robust antibody purification by optimizing protein‐A chromatography in combination with precipitation methodologies S Chollangi, R Parker, N Singh, Y Li, M Borys, Z Li Biotechnology and Bioengineering 112 (11), 2292-2304, 2015 | 102 | 2015 |
Modeling kinetics of a large‐scale fed‐batch CHO cell culture by Markov chain Monte Carlo method Z Xing, N Bishop, K Leister, ZJ Li Biotechnology progress 26 (1), 208-219, 2010 | 99 | 2010 |
Clarification technologies for monoclonal antibody manufacturing processes: Current state and future perspectives N Singh, A Arunkumar, S Chollangi, ZG Tan, M Borys, ZJ Li Biotechnology and bioengineering 113 (4), 698-716, 2016 | 98 | 2016 |
Effects of culture conditions on N‐glycolylneuraminic acid (Neu5Gc) content of a recombinant fusion protein produced in CHO cells MC Borys, NG Dalal, NR Abu‐Absi, SF Khattak, Y Jing, Z Xing, ZJ Li Biotechnology and bioengineering 105 (6), 1048-1057, 2010 | 91 | 2010 |
Cell culture and gene transcription effects of copper sulfate on Chinese hamster ovary cells Y Qian, SF Khattak, Z Xing, A He, PS Kayne, NX Qian, SH Pan, ZJ Li Biotechnology progress 27 (4), 1190-1194, 2011 | 87 | 2011 |
The use of ‘Omics technology to rationally improve industrial mammalian cell line performance AM Lewis, NR Abu‐Absi, MC Borys, ZJ Li Biotechnology and bioengineering 113 (1), 26-38, 2016 | 83 | 2016 |
Identification of cell culture conditions to control protein aggregation of IgG fusion proteins expressed in Chinese hamster ovary cells Y Jing, M Borys, S Nayak, S Egan, Y Qian, SH Pan, ZJ Li Process Biochemistry 47 (1), 69-75, 2012 | 82 | 2012 |
NMR-based metabolomics of mammalian cell and tissue cultures N Aranibar, M Borys, NA Mackin, V Ly, N Abu-Absi, S Abu-Absi, M Niemitz, ... Journal of biomolecular NMR 49, 195-206, 2011 | 80 | 2011 |
Combined metabolomics and proteomics reveals hypoxia as a cause of lower productivity on scale‐up to a 5000‐liter CHO bioprocess Y Gao, S Ray, S Dai, AR Ivanov, NR Abu‐Absi, AM Lewis, Z Huang, ... Biotechnology journal 11 (9), 1190-1200, 2016 | 75 | 2016 |
Transcriptomic responses to sodium chloride‐induced osmotic stress: A study of industrial fed‐batch CHO cell cultures D Shen, TR Kiehl, SF Khattak, ZJ Li, A He, PS Kayne, V Patel, ... Biotechnology progress 26 (4), 1104-1115, 2010 | 73 | 2010 |
Identifying inhibitory threshold values of repressing metabolites in CHO cell culture using multivariate analysis methods Z Xing, Z Li, V Chow, SS Lee Biotechnology progress 24 (3), 675-683, 2008 | 69 | 2008 |
Development of an intensified fed-batch production platform with doubled titers using N-1 perfusion seed for cell culture manufacturing J Xu, MS Rehmann, M Xu, S Zheng, C Hill, Q He, MC Borys, ZJ Li Bioresources and Bioprocessing 7, 1-16, 2020 | 68 | 2020 |
Effects of Increased Impeller Power in a Production‐Scale Aspergillusoryzae Fermentation ZJ Li, V Shukla, KS Wenger, AP Fordyce, AG Pedersen, MR Marten Biotechnology Progress 18 (3), 437-444, 2002 | 68 | 2002 |
Observations of cell size dynamics under osmotic stress TR Kiehl, D Shen, SF Khattak, Z Jian Li, ST Sharfstein Cytometry Part A 79 (7), 560-569, 2011 | 67 | 2011 |