Long-term expansion of functional mouse and human hepatocytes as 3D organoids H Hu, H Gehart, B Artegiani, C LÖpez-Iglesias, F Dekkers, O Basak, ... Cell 175 (6), 1591-1606. e19, 2018 | 628 | 2018 |
Tubuloids derived from human adult kidney and urine for personalized disease modeling F Schutgens, MB Rookmaaker, T Margaritis, A Rios, C Ammerlaan, ... Nature biotechnology 37 (3), 303-313, 2019 | 364 | 2019 |
Modelling Cryptosporidium infection in human small intestinal and lung organoids I Heo, D Dutta, DA Schaefer, N Iakobachvili, B Artegiani, N Sachs, ... Nature microbiology 3 (7), 814-823, 2018 | 353 | 2018 |
Regulation of cerebral cortex size and folding by expansion of basal progenitors M Nonaka‐Kinoshita, I Reillo, B Artegiani, M Ángeles Martínez‐Martínez, ... The EMBO journal 32 (13), 1817-1828, 2013 | 241 | 2013 |
Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient J Beumer, B Artegiani, Y Post, F Reimann, F Gribble, TN Nguyen, H Zeng, ... Nature cell biology 20 (8), 909-916, 2018 | 232 | 2018 |
A single-cell RNA sequencing study reveals cellular and molecular dynamics of the hippocampal neurogenic niche B Artegiani, A Lyubimova, M Muraro, JH van Es, A van Oudenaarden, ... Cell reports 21 (11), 3271-3284, 2017 | 223 | 2017 |
Fast and efficient generation of knock-in human organoids using homology-independent CRISPR–Cas9 precision genome editing B Artegiani, D Hendriks, J Beumer, R Kok, X Zheng, I Joore, ... Nature cell biology 22 (3), 321-331, 2020 | 197 | 2020 |
Use and application of 3D-organoid technology B Artegiani, H Clevers Human molecular genetics 27 (R2), R99-R107, 2018 | 192 | 2018 |
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ... Cell stem cell 28 (5), 816-832, 2021 | 178 | 2021 |
Probing the tumor suppressor function of BAP1 in CRISPR-engineered human liver organoids B Artegiani, L van Voorthuijsen, RGH Lindeboom, D Seinstra, I Heo, ... Cell Stem Cell 24 (6), 927-943. e6, 2019 | 159 | 2019 |
High-resolution mRNA and secretome atlas of human enteroendocrine cells J Beumer, J Puschhof, J Bauzá-Martinez, A Martínez-Silgado, ... Cell 181 (6), 1291-1306. e19, 2020 | 145 | 2020 |
Overexpression of cdk4 and cyclinD1 triggers greater expansion of neural stem cells in the adult mouse brain B Artegiani, D Lindemann, F Calegari Journal of Experimental Medicine 208 (5), 937-948, 2011 | 144 | 2011 |
Increasing neurogenesis refines hippocampal activity rejuvenating navigational learning strategies and contextual memory throughout life G Berdugo-Vega, G Arias-Gil, A López-Fernández, B Artegiani, ... Nature communications 11 (1), 135, 2020 | 142 | 2020 |
CRISPR-Cas tools and their application in genetic engineering of human stem cells and organoids D Hendriks, H Clevers, B Artegiani Cell stem cell 27 (5), 705-731, 2020 | 123 | 2020 |
Age-related cognitive decline: can neural stem cells help us? B Artegiani, F Calegari Aging (Albany NY) 4 (3), 176, 2012 | 106 | 2012 |
Establishment of human fetal hepatocyte organoids and CRISPR–Cas9-based gene knockin and knockout in organoid cultures from human liver D Hendriks, B Artegiani, H Hu, S Chuva de Sousa Lopes, H Clevers Nature Protocols 16 (1), 182-217, 2021 | 87 | 2021 |
PRMT6 regulates RAS/RAF binding and MEK/ERK-mediated cancer stemness activities in hepatocellular carcinoma through CRAF methylation LH Chan, L Zhou, KY Ng, TL Wong, TK Lee, R Sharma, JH Loong, ... Cell reports 25 (3), 690-701. e8, 2018 | 84 | 2018 |
Tox: a multifunctional transcription factor and novel regulator of mammalian corticogenesis B Artegiani, AM de Jesus Domingues, S Bragado Alonso, E Brandl, ... The EMBO journal 34 (7), 896-910, 2015 | 54 | 2015 |
Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis D Hendriks, JF Brouwers, K Hamer, MH Geurts, L Luciana, S Massalini, ... Nature Biotechnology 41 (11), 1567-1581, 2023 | 50 | 2023 |
The interaction with HMG20a/b proteins suggests a potential role for β-dystrobrevin in neuronal differentiation B Artegiani, C Labbaye, A Sferra, MT Quaranta, P Torreri, G Macchia, ... Journal of Biological Chemistry 285 (32), 24740-24750, 2010 | 37 | 2010 |