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Neville Bethel
Neville Bethel
Postdoctoral Fellow, Institute for Protein Design, University of Washington
在 uw.edu 的电子邮件经过验证 - 首页
标题
引用次数
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年份
Robust deep learning–based protein sequence design using ProteinMPNN
J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ...
Science 378 (6615), 49-56, 2022
6802022
Atomistic insight into lipid translocation by a TMEM16 scramblase
NP Bethel, M Grabe
Proceedings of the National Academy of Sciences 113 (49), 14049-14054, 2016
1032016
The sixth transmembrane segment is a major gating component of the TMEM16A calcium-activated chloride channel
CJ Peters, JM Gilchrist, J Tien, NP Bethel, L Qi, T Chen, L Wang, YN Jan, ...
Neuron 97 (5), 1063-1077. e4, 2018
822018
Computational design of mechanically coupled axle-rotor protein assemblies
A Courbet, J Hansen, Y Hsia, N Bethel, YJ Park, C Xu, A Moyer, ...
Science 376 (6591), 383-390, 2022
492022
Continuum descriptions of membranes and their interaction with proteins: towards chemically accurate models
D Argudo, NP Bethel, FV Marcoline, M Grabe
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (7), 1619-1634, 2016
452016
New continuum approaches for determining protein-induced membrane deformations
D Argudo, NP Bethel, FV Marcoline, CW Wolgemuth, M Grabe
Biophysical journal 112 (10), 2159-2172, 2017
412017
Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substrates
CJ Guerriero, KR Reutter, AA Augustine, GM Preston, KF Weiberth, ...
Molecular biology of the cell 28 (15), 2076-2090, 2017
372017
Membrane protein properties revealed through data-rich electrostatics calculations
FV Marcoline, N Bethel, CJ Guerriero, JL Brodsky, M Grabe
Structure 23 (8), 1526-1537, 2015
362015
Chemically induced vesiculation as a platform for studying TMEM16F activity
TW Han, W Ye, NP Bethel, M Zubia, A Kim, KH Li, AL Burlingame, ...
Proceedings of the National Academy of Sciences 116 (4), 1309-1318, 2019
312019
Dynamic hydraulic fluid stimulation regulated intramedullary pressure
M Hu, F Serra-Hsu, N Bethel, L Lin, S Ferreri, J Cheng, YX Qin
Bone 57 (1), 137-141, 2013
192013
A multiscale model of mechanotransduction by the ankyrin chains of the NOMPC channel
D Argudo, S Capponi, NP Bethel, M Grabe
Journal of General Physiology 151 (3), 316-327, 2019
172019
Interrelation between external oscillatory muscle coupling amplitude and in vivo intramedullary pressure related bone adaptation
M Hu, J Cheng, N Bethel, F Serra-Hsu, S Ferreri, L Lin, YX Qin
Bone 66, 178-181, 2014
142014
Natural and designed proteins inspired by extremotolerant organisms can form condensates and attenuate apoptosis in human cells
MT Veling, DT Nguyen, NN Thadani, ME Oster, NJ Rollins, KP Brock, ...
ACS synthetic biology 11 (3), 1292-1302, 2022
132022
Precisely patterned nanofibres made from extendable protein multiplexes
NP Bethel, AJ Borst, F Parmeggiani, MJ Bick, TJ Brunette, H Nguyen, ...
Nature Chemistry 15 (12), 1664-1671, 2023
92023
Blueprinting extendable nanomaterials with standardized protein blocks
TF Huddy, Y Hsia, RD Kibler, J Xu, N Bethel, D Nagarajan, R Redler, ...
Nature 627 (8005), 898-904, 2024
72024
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies
NI Edman, A Phal, RL Redler, T Schlichthaerle, SR Srivatsan, DD Ehnes, ...
Cell 187 (14), 3726-3740. e43, 2024
42024
De novo design of pH-responsive self-assembling helical protein filaments
H Shen, EM Lynch, S Akkineni, JL Watson, J Decarreau, NP Bethel, ...
Nature Nanotechnology, 1-6, 2024
32024
Computational design of nanoscale rotational mechanics in de novo protein assemblies
A Courbet, J Hansen, Y Hsia, N Bethel, YJ Park, C Xu, A Moyer, ...
bioRxiv, 2021.11. 11.468255, 2021
32021
Blueprinting expandable nanomaterials with standardized protein building blocks
TF Huddy, Y Hsia, RD Kibler, J Xu, N Bethel, D Nagarajan, R Redler, ...
bioRxiv, 2023.06. 09.544258, 2023
12023
Local structural flexibility drives oligomorphism in computationally designed protein assemblies
A Khmelinskaia, NP Bethel, F Fatehi, A Antanasijevic, AJ Borst, SH Lai, ...
bioRxiv, 2023.10. 18.562842, 2023
12023
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