Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration R Ishimura, G Nagy, I Dotu, H Zhou, XL Yang, P Schimmel, S Senju, ... Science 345 (6195), 455-459, 2014 | 442 | 2014 |
Longitudinal molecular trajectories of diffuse glioma in adults FP Barthel, KC Johnson, FS Varn, AD Moskalik, G Tanner, E Kocakavuk, ... Nature 576 (7785), 112-120, 2019 | 412 | 2019 |
A molecular-imprint nanosensor for ultrasensitive detection of proteins D Cai, L Ren, H Zhao, C Xu, L Zhang, Y Yu, H Wang, Y Lan, MF Roberts, ... Nature nanotechnology 5 (8), 597-601, 2010 | 404 | 2010 |
Anomalous dynamics of translocation J Chuang, Y Kantor, M Kardar Physical Review E 65 (1), 011802, 2001 | 363 | 2001 |
Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer MA Kiebish, X Han, H Cheng, JH Chuang, TN Seyfried Journal of lipid research 49 (12), 2545-2556, 2008 | 341 | 2008 |
A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology KP Guillen, M Fujita, AJ Butterfield, SD Scherer, MH Bailey, Z Chu, ... Nature cancer 3 (2), 232-250, 2022 | 173 | 2022 |
Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation R Ishimura, G Nagy, I Dotu, JH Chuang, SL Ackerman Elife 5, e14295, 2016 | 168 | 2016 |
Functional bias and spatial organization of genes in mutational hot and cold regions in the human genome JH Chuang, H Li PLoS biology 2 (2), e29, 2004 | 166 | 2004 |
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts XY Woo, J Giordano, A Srivastava, ZM Zhao, MW Lloyd, R de Bruijn, ... Nature genetics 53 (1), 86-99, 2021 | 152 | 2021 |
Deep learning-based cross-classifications reveal conserved spatial behaviors within tumor histological images J Noorbakhsh, S Farahmand, A Foroughi Pour, S Namburi, D Caruana, ... Nature communications 11 (1), 6367, 2020 | 144 | 2020 |
Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria MA Kiebish, X Han, H Cheng, A Lunceford, CF Clarke, H Moon, ... Journal of neurochemistry 106 (1), 299-312, 2008 | 140 | 2008 |
Integrating chemical footprinting data into RNA secondary structure prediction K Zarringhalam, MM Meyer, I Dotu, JH Chuang, P Clote Public Library of Science 7 (10), e45160, 2012 | 109 | 2012 |
Multiple point adsorption in a heteropolymer gel and the Tanaka approach to imprinting: experiment and theory K Ito, J Chuang, C Alvarez-Lorenzo, T Watanabe, N Ando, AY Grosberg Progress in polymer science 28 (10), 1489-1515, 2003 | 104 | 2003 |
The tandem duplicator phenotype as a distinct genomic configuration in cancer F Menghi, K Inaki, XY Woo, PA Kumar, KR Grzeda, A Malhotra, V Yadav, ... Proceedings of the National Academy of Sciences 113 (17), E2373-E2382, 2016 | 101 | 2016 |
Effect of Reversible Cross-linker, N,N‘-Bis(acryloyl)cystamine, on Calcium Ion Adsorption by Imprinted Gels H Hiratani, C Alvarez-Lorenzo, J Chuang, O Guney, AY Grosberg, ... Langmuir 17 (14), 4431-4436, 2001 | 84 | 2001 |
A systematic approach to identify functional motifs within vertebrate developmental enhancers Q Li, D Ritter, N Yang, Z Dong, H Li, JH Chuang, S Guo Developmental biology 337 (2), 484-495, 2010 | 82 | 2010 |
Deep learning trained on hematoxylin and eosin tumor region of Interest predicts HER2 status and trastuzumab treatment response in HER2+ breast cancer S Farahmand, AI Fernandez, FS Ahmed, DL Rimm, JH Chuang, ... Modern Pathology 35 (1), 44-51, 2022 | 79 | 2022 |
Mutations in DNA repair genes are associated with increased neoantigen burden and a distinct immunophenotype in lung squamous cell carcinoma YK Chae, JF Anker, MS Oh, P Bais, S Namburi, S Agte, FJ Giles, ... Scientific reports 9 (1), 3235, 2019 | 79 | 2019 |
Frustrations in polymer conformation in gels and their minimization through molecular imprinting T Enoki, K Tanaka, T Watanabe, T Oya, T Sakiyama, Y Takeoka, K Ito, ... Physical review letters 85 (23), 5000, 2000 | 79 | 2000 |
Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment H Sun, S Cao, RJ Mashl, CK Mo, S Zaccaria, MC Wendl, SR Davies, ... Nature communications 12 (1), 5086, 2021 | 74 | 2021 |