关注
Alejandro Parrales
Alejandro Parrales
University of Kansas Cancer Center
在 kumc.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Targeting oncogenic mutant p53 for cancer therapy
A Parrales, T Iwakuma
Frontiers in oncology 5, 288, 2015
3622015
Mutant p53 suppresses innate immune signaling to promote tumorigenesis
M Ghosh, S Saha, J Bettke, R Nagar, A Parrales, T Iwakuma, ...
Cancer cell 39 (4), 494-508. e5, 2021
2142021
DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway
A Parrales, A Ranjan, SV Iyer, S Padhye, SJ Weir, A Roy, T Iwakuma
Nature cell biology 18 (11), 1233-1243, 2016
2072016
p53 as a regulator of lipid metabolism in cancer
A Parrales, T Iwakuma
International journal of molecular sciences 17 (12), 2074, 2016
1052016
The interplay between mutant p53 and the mevalonate pathway
A Parrales, E Thoenen, T Iwakuma
Cell Death & Differentiation 25 (3), 460-470, 2018
922018
ERK1/2-dependent activation of mTOR/mTORC1/p70S6K regulates thrombin-induced RPE cell proliferation
A Parrales, E López, I Lee-Rivera, AM López-Colomé
Cellular Signalling 25 (4), 829-838, 2013
502013
Thrombin stimulates RPE cell proliferation by promoting c‐Fos‐mediated cyclin D1 expression
A Parrales, JP Palma‐Nicolás, E López, AM López‐Colomé
Journal of cellular physiology 222 (2), 302-312, 2010
442010
Thrombin activation of PI3K/PDK1/Akt signaling promotes cyclin D1 upregulation and RPE cell proliferation
A Parrales, E Lopez, AM Lopez-Colome
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (10), 1758-1766, 2011
412011
Genome-wide RNAi screening identifies TMIGD3 isoform1 as a suppressor of NF-κB and osteosarcoma progression
SV Iyer, A Ranjan, HK Elias, A Parrales, H Sasaki, BC Roy, S Umar, ...
Nature Communications 7 (1), 13561, 2016
332016
Comparative oncology approach to drug repurposing in osteosarcoma
A Parrales, P McDonald, M Ottomeyer, A Roy, FJ Shoenen, M Broward, ...
PLoS One 13 (3), e0194224, 2018
302018
Allele-specific silencing of mutant p53 attenuates dominant-negative and gain-of-function activities
SV Iyer, A Parrales, P Begani, A Narkar, AS Adhikari, LA Martinez, ...
Oncotarget 7 (5), 5401, 2016
292016
DNAJA1 promotes cancer metastasis through interaction with mutant p53
A Kaida, S Yamamoto, A Parrales, ED Young, A Ranjan, MA Alalem, ...
Oncogene 40 (31), 5013-5025, 2021
222021
Mutant p53 depletion by novel inhibitors for HSP40/J-domain proteins derived from the natural compound plumbagin
M Alalem, M Bhosale, A Ranjan, S Yamamoto, A Kaida, S Nishikawa, ...
Cancers 14 (17), 4187, 2022
112022
Unsaturated fatty acids regulate stemness of ovarian cancer cells through NF-κB
A Parrales, A Ranjan, T Iwakuma
Stem cell investigation 4, 2017
112017
Thrombin promotes the expression of Ccnd1 gene in RPE cells through the activation of converging signaling pathways
I Lee-Rivera, E López, A Parrales, A Alvarez-Arce, AM López-Colomé
Experimental eye research 139, 81-89, 2015
112015
DNAJA1-and conformational mutant p53-dependent inhibition of cancer cell migration by a novel compound identified through a virtual screen
S Nishikawa, A Kaida, A Parrales, A Ranjan, M Alalem, H Ren, ...
Cell Death Discovery 8 (1), 437, 2022
72022
Targeting oncogenic mutant p53 for cancer therapy. Front Oncol. 2015; 5: 288
A Parrales, T Iwakuma
62015
Perinucleolar compartment (PNC) prevalence as an independent prognostic factor in pediatric ewing sarcoma: a multi-institutional study
E Gonzalez, AA Ahmed, L McCarthy, K Chastain, S Habeebu, ...
Cancers 15 (8), 2230, 2023
32023
TAp63–miRNA–AURKA Axis as a Therapeutic Target for Cutaneous Squamous Cell Carcinoma
A Parrales, T Iwakuma
Cancer research 80 (12), 2439-2440, 2020
12020
Abstract LB303: Suppression of stress granule formation is a novel vulnerability imposed by mutant p53
E Thoenen, A Ranjan, A Parrales, S Nishikawa, D Dixon, S Oka, ...
Cancer Research 84 (7_Supplement), LB303-LB303, 2024
2024
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