Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer RJANS Zhenfei Li, Andrew C. Bishop, Mohammad Alyamani, Jorge A. Garcia ... Nature 523 (7560), 347-351, 2015 | 290 | 2015 |
Adrenal-derived 11-Oxygenated 19-Carbon Steroids are the Dominant Androgens in Classic 21-Hydroxylase Deficiency AFTATNRCSKUTGJJSDPMWRR Auchus European Journal of Endocrinology 174, 601-609, 2016 | 208 | 2016 |
Redirecting abiraterone metabolism to biochemically fine tune prostate cancer anti-androgen therapy NS Zhenfei Li, Mohammad Alyammani, Jianneng Li, Kevin Rogacki, Mohamed ... Nature 533, 547-551, 2016 | 168 | 2016 |
High-affinity small-molecule inhibitors of the menin-mixed lineage leukemia (MLL) interaction closely mimic a natural protein–protein interaction S He, TJ Senter, J Pollock, C Han, SK Upadhyay, T Purohit, RD Gogliotti, ... Journal of medicinal chemistry 57 (4), 1543-1556, 2014 | 112 | 2014 |
HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer M Alyamani, H Emamekhoo, S Park, J Taylor, N Almassi, S Upadhyay, ... The Journal of clinical investigation 128 (8), 3333-3340, 2018 | 50 | 2018 |
Steroidogenic Metabolism of Galeterone Reveals a Diversity of Biochemical Activities RJANS Mohammad Alyamani,Zhenfei Li,Michael Berk,Jianneng Li, Jingjie Tang ... Cell Chemical Biology 24, 825-832, 2017 | 50 | 2017 |
A-ring modified steroidal azoles retaining similar potent and slowly reversible CYP17A1 inhibition as abiraterone M Garrido, HM Peng, FK Yoshimoto, SK Upadhyay, E Bratoeff, RJ Auchus The Journal of steroid biochemistry and molecular biology 143, 1-10, 2014 | 39 | 2014 |
Comparison of microwave-assisted and conventional preparations of cyclic imides SK Upadhyay, SRK Pingali, BS Jursic Tetrahedron Letters 51 (17), 2215-2217, 2010 | 38 | 2010 |
Development and Validation of a Novel LC-MS/MS Method for Simultaneous Determination of Abiraterone and Its Seven Metabolites in Human Serum: Innovation in Separation of … MAZLSKUDARJAN Sharifi Journal of Steroidal Biochemistry and Molecular Biology 172, 231-239, 2017 | 31* | 2017 |
Microwave-assisted benzyl mono-and dibromination in diethyl carbonate as environmentally friendly alternative to radical bromination in carbon tetrachloride SRK Pingali, SK Upadhyay, BS Jursic Green chemistry 13 (4), 928-933, 2011 | 27 | 2011 |
menin-MLL inhibitors and methods of use thereof TJS Jolanta Grembecka, Tomasz Cierpicki, Sunil Kumar Upadhyay, Shaun R ... WO Patent WO 2014200479 A1 20,141,218, 2014 | 20* | 2014 |
Novel and efficient synthesis and antifungal evaluation of 2, 3-functionalized cholestane and androstane derivatives BS Jursic, SK Upadhyay, CC Creech, DM Neumann Bioorganic & medicinal chemistry letters 20 (24), 7372-7375, 2010 | 19 | 2010 |
Visible-Light-Driven Oxidative Mono-and Dibromination of Benzylic sp3 C–H Bonds with Potassium Bromide/Oxone at Room Temperature M Zhao, M Li, W Lu Synthesis 50 (24), 4933-4939, 2018 | 18 | 2018 |
Afatinib use in non-small cell lung cancer previously sensitive to epidermal growth factor receptor inhibitors: The United Kingdom Named Patient Programme F Khan, C Ottensmeier, S Popat, D Dua, N Dorey, S Ellis, M Szabo, ... European journal of cancer 50 (10), 1717-1721, 2014 | 15 | 2014 |
Synthesis and antifungal activity of functionalized 2, 3-spirostane isomers SK Upadhyay, CC Creech, KL Bowdy, ED Stevens, BS Jursic, ... Bioorganic & medicinal chemistry letters 21 (10), 2826-2831, 2011 | 15 | 2011 |
Antifungal activity of 2α, 3β-functionalized steroids stereoselectively increases with the addition of oligosaccharides A Cammarata, SK Upadhyay, BS Jursic, DM Neumann Bioorganic & medicinal chemistry letters 21 (24), 7379-7386, 2011 | 9 | 2011 |
Sulfur Betaines from S-Propargyl Xanthates. Unusual Chemistry from a Simple Functional Group SZ Zard Synthesis 51 (05), 1006-1020, 2019 | 7 | 2019 |
HSD3B1 genotype and abiraterone (Abi) metabolites in patients (pts) with prostate cancer (PCa). H Emamekhoo, M Alyamani, S Park, J Taylor, N Almassi, S Upadhyay, ... Journal of Clinical Oncology 36 (6_suppl), 325-325, 2018 | 5 | 2018 |
Microwave-Assisted NBS Bromination of p-Iminotoluenes: Preparation of New Alcohol, Mercapto, and Amino Protection Groups SK Upadhyay, BS Jursic Synthetic Communications 41 (21), 3177-3185, 2011 | 4 | 2011 |
A socio-economic analysis of fish farming in Gonda and Basti districts, Uttar Pradesh. SK Upadhyay, J Mishra | 2 | 2020 |