An integrated encyclopedia of DNA elements in the human genome E consortium Nature 447, 57-74, 2012 | 16856* | 2012 |
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Management Group Liefer Laura A. 51 Wetterstrand Kris A. 51 Good Peter J. 51 ... nature 447 (7146), 799-816, 2007 | 5993 | 2007 |
Histone acetylation and transcriptional regulatory mechanisms K Struhl Genes & development 12 (5), 599-606, 1998 | 2449 | 1998 |
The ENCODE (ENCyclopedia of DNA elements) project EA Feingold, PJ Good, MS Guyer, S Kamholz, L Liefer, K Wetterstrand, ... Science 306 (5696), 636-640, 2004 | 2399 | 2004 |
High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules. K Struhl, DT Stinchcomb, S Scherer, RW Davis Proceedings of the National Academy of Sciences 76 (3), 1035-1039, 1979 | 1749 | 1979 |
An epigenetic switch involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation D Iliopoulos, HA Hirsch, K Struhl Cell 139 (4), 693-706, 2009 | 1650 | 2009 |
Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs S Cawley, S Bekiranov, HH Ng, P Kapranov, EA Sekinger, D Kampa, ... Cell 116 (4), 499-509, 2004 | 1433 | 2004 |
Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity HH Ng, F Robert, RA Young, K Struhl Molecular cell 11 (3), 709-719, 2003 | 1404 | 2003 |
Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission HA Hirsch, D Iliopoulos, PN Tsichlis, K Struhl Cancer research 69 (19), 7507-7511, 2009 | 1366 | 2009 |
The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α helices: crystal structure of the protein-DNA complex TE Ellenberger, CJ Brandl, K Struhl, SC Harrison Cell 71 (7), 1223-1237, 1992 | 1306 | 1992 |
Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast IA Hope, K Struhl Cell 46 (6), 885-894, 1986 | 1150 | 1986 |
Isolation and characterisation of a yeast chromosomal replicator DT Stinchcomb, K Struhl, RW Davis Nature 282 (5734), 39-43, 1979 | 1115 | 1979 |
Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain Q Feng, H Wang, HH Ng, H Erdjument-Bromage, P Tempst, K Struhl, ... Current biology 12 (12), 1052-1058, 2002 | 1049 | 2002 |
TREX is a conserved complex coupling transcription with messenger RNA export K Sträßer, S Masuda, P Mason, J Pfannstiel, M Oppizzi, ... Nature 417 (6886), 304-308, 2002 | 1045 | 2002 |
Sterile host yeasts (SHY): a eukaryotic system of biological containment for recombinant DNA experiments D Botstein, SC Falco, SE Stewart, M Brennan, S Scherer, DT Stinchcomb, ... Gene 8 (1), 17-24, 1979 | 1019 | 1979 |
STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer D Iliopoulos, SA Jaeger, HA Hirsch, ML Bulyk, K Struhl Molecular cell 39 (4), 493-506, 2010 | 1002 | 2010 |
Current Protocols in Molecular Biology FM Ausubel, R Brent, RE Kingston, DD Moore, JG Seidman, JA Smith, ... | 895* | |
A user's guide to the encyclopedia of DNA elements (ENCODE) ENCODE Project Consortium PLoS biology 9 (4), e1001046, 2011 | 856 | 2011 |
The TAFs in the HAT K Struhl, Z Moqtaderi Cell 94, 1-4, 1998 | 832 | 1998 |
The gradient morphogen bicoid is a concentration-dependent transcriptional activator G Struhl, K Struhl, PM Macdonald Cell 57 (7), 1259-1273, 1989 | 815 | 1989 |