| PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex P Liu, W Gan, YR Chin, K Ogura, J Guo, J Zhang, B Wang, J Blenis, ... Cancer discovery 5 (11), 1194-1209, 2015 | 409 | 2015 |
| Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer YR Chin, A Toker Cellular signalling 21 (4), 470-476, 2009 | 322 | 2009 |
| Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction D Gao, H Inuzuka, A Tseng, RY Chin, A Toker, W Wei Nature cell biology 11 (4), 397-408, 2009 | 282 | 2009 |
| mTOR drives its own activation via SCFβTrCP-dependent degradation of the mTOR inhibitor DEPTOR D Gao, H Inuzuka, MKM Tan, H Fukushima, JW Locasale, P Liu, L Wan, ... Molecular cell 44 (2), 290-303, 2011 | 273 | 2011 |
| Acetylation-dependent regulation of Skp2 function H Inuzuka, D Gao, LWS Finley, W Yang, L Wan, H Fukushima, YR Chin, ... Cell 150 (1), 179-193, 2012 | 223 | 2012 |
| The actin-bundling protein palladin is an Akt1-specific substrate that regulates breast cancer cell migration YR Chin, A Toker Molecular cell 38 (3), 333-344, 2010 | 206 | 2010 |
| 3-phosphoinositide–dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma M Maurer, T Su, LH Saal, S Koujak, BD Hopkins, CR Barkley, J Wu, ... Cancer research 69 (15), 6299-6306, 2009 | 168 | 2009 |
| Targeting Akt3 signaling in triple-negative breast cancer YR Chin, T Yoshida, A Marusyk, AH Beck, K Polyak, A Toker Cancer research 74 (3), 964-973, 2014 | 167 | 2014 |
| NFAT promotes carcinoma invasive migration through glypican-6 GK Yiu, A Kaunisto, YR Chin, A Toker Biochemical Journal 440 (1), 157-166, 2011 | 110 | 2011 |
| Inhibition of Rb phosphorylation leads to mTORC2-mediated activation of Akt J Zhang, K Xu, P Liu, Y Geng, B Wang, W Gan, J Guo, F Wu, YR Chin, ... Molecular cell 62 (6), 929-942, 2016 | 104 | 2016 |
| Akt/protein kinase B and glycogen synthase kinase-3β signaling pathway regulates cell migration through the NFAT1 transcription factor M Yoeli-Lerner, YR Chin, CK Hansen, A Toker Molecular Cancer Research 7 (3), 425-432, 2009 | 96 | 2009 |
| Akt isoform-specific signaling in breast cancer: uncovering an anti-migratory role for palladin YR Chin, A Toker Cell adhesion & migration 5 (3), 211-214, 2011 | 90 | 2011 |
| PTEN-deficient tumors depend on AKT2 for maintenance and survival YR Chin, X Yuan, SP Balk, A Toker Cancer discovery 4 (8), 942-955, 2014 | 85 | 2014 |
| Defining super-enhancer landscape in triple-negative breast cancer by multiomic profiling H Huang, J Hu, A Maryam, Q Huang, Y Zhang, S Ramakrishnan, J Li, ... Nature communications 12 (1), 2242, 2021 | 74 | 2021 |
| Upregulation of AKT3 confers resistance to the AKT inhibitor MK2206 in breast cancer C Stottrup, T Tsang, YR Chin Molecular cancer therapeutics 15 (8), 1964-1974, 2016 | 65 | 2016 |
| RhoB differentially controls Akt function in tumor cells and stromal endothelial cells during breast tumorigenesis S Kazerounian, D Gerald, M Huang, YR Chin, D Udayakumar, N Zheng, ... Cancer research 73 (1), 50-61, 2013 | 59 | 2013 |
| PtdIns (3, 4, 5) P3-Dependent Activation of the mTORC2 Kinase Complex. Cancer Discov. 2015; 5: 1194–1209. doi: 10.1158/2159-8290 P Liu, W Gan, YR Chin, K Ogura, J Guo, J Zhang, B Wang, J Blenis, ... CD-15-0460.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 58 | |
| Akt2 regulates expression of the actin-bundling protein palladin YR Chin, A Toker FEBS letters 584 (23), 4769-4774, 2010 | 45 | 2010 |
| Inhibition of tumor necrosis factor (TNF) signal transduction by the adenovirus group C RID complex involves downregulation of surface levels of TNF receptor 1 SP Fessler, YR Chin, MS Horwitz Journal of virology 78 (23), 13113-13121, 2004 | 45 | 2004 |
| Mechanism for removal of tumor necrosis factor receptor 1 from the cell surface by the adenovirus RIDα/β complex YR Chin, MS Horwitz Journal of virology 79 (21), 13606-13617, 2005 | 42 | 2005 |
