Gold‐Catalyzed Intermolecular Anti‐Markovnikov Hydroamination of Alkylidenecyclopropanes JC Timmerman, BD Robertson, RA Widenhoefer Angewandte Chemie 127 (7), 2279-2282, 2015 | 63 | 2015 |
Data-driven multi-objective optimization tactics for catalytic asymmetric reactions using bisphosphine ligands JJ Dotson, L van Dijk, JC Timmerman, S Grosslight, RC Walroth, ... Journal of the American Chemical Society 145 (1), 110-121, 2022 | 45 | 2022 |
Enantioselective Intramolecular Hydroamination of Unactivated Alkenes Catalyzed by Mono‐and Bis (gold) Phosphine Complexes SD Lee, JC Timmerman, RA Widenhoefer Advanced Synthesis & Catalysis 356 (14‐15), 3187-3192, 2014 | 32 | 2014 |
Atroposelective Negishi coupling optimization guided by multivariate linear regression analysis: asymmetric synthesis of KRAS G12C covalent inhibitor GDC-6036 J Xu, S Grosslight, KA Mack, SC Nguyen, K Clagg, NK Lim, ... Journal of the American Chemical Society 144 (45), 20955-20963, 2022 | 29 | 2022 |
Gold‐Catalyzed Intermolecular anti‐Markovnikov Hydroamination of Methylenecyclopropanes with 2‐Pyridones JC Timmerman, RA Widenhoefer Advanced Synthesis & Catalysis 357 (16‐17), 3703-3706, 2015 | 28 | 2015 |
Gold (I)-catalyzed intramolecular hydroamination of unactivated terminal and internal alkenes with 2-pyridones JC Timmerman, S Laulhé, RA Widenhoefer Organic letters 19 (6), 1466-1469, 2017 | 27 | 2017 |
Gold-Catalyzed Intermolecular, anti-Markovnikov Hydroarylation of Methylenecyclopropanes with Indoles JC Timmerman, WW Schmitt, RA Widenhoefer Organic letters 18 (19), 4966-4969, 2016 | 27 | 2016 |
High-level data fusion enables the chemoinformatically guided discovery of chiral disulfonimide catalysts for atropselective iodination of 2-amino-6-arylpyridines BT Rose, JC Timmerman, SA Bawel, S Chin, H Zhang, SE Denmark Journal of the American Chemical Society 144 (50), 22950-22964, 2022 | 22 | 2022 |
Total synthesis of caesalpinnone A and caesalpinflavan B: Evolution of a concise strategy JC Timmerman, NJ Sims, JL Wood Journal of the American Chemical Society 141 (25), 10082-10090, 2019 | 16 | 2019 |
Preparation, structures and preliminary host–guest studies of fluorinated syn-bis-quinoxaline molecular tweezers M Etzkorn, JC Timmerman, MD Brooker, X Yu, M Gerken Beilstein Journal of Organic Chemistry 6 (1), 39, 2010 | 15 | 2010 |
Formal Synthesis of (+)‐Laurencin by Gold (I)‐Catalyzed Intramolecular Dehydrative Alkoxylation ML Lanier, H Park, P Mukherjee, JC Timmerman, AA Ribeiro, ... Chemistry–A European Journal 23 (30), 7180-7184, 2017 | 13 | 2017 |
Second-generation atroposelective synthesis of KRAS G12C covalent inhibitor GDC-6036 J Xu, NK Lim, JC Timmerman, J Shen, K Clagg, U Orcel, R Bigler, ... Organic Letters 25 (19), 3417-3422, 2023 | 11 | 2023 |
Synthesis and biological evaluation of hippolachnin A analogues JC Timmerman, JL Wood Organic letters 20 (13), 3788-3792, 2018 | 10 | 2018 |
Kinetics and Mechanism of the Gold‐Catalyzed Hydroamination of 1,1‐Dimethylallene with N‐Methylaniline RJ Harris, K Nakafuku, AN Duncan, RG Carden, JC Timmerman, ... Chemistry–A European Journal 27 (40), 10377-10386, 2021 | 4 | 2021 |
Data-driven multi-objective optimization tactics for catalytic asymmetric reactions J Dotson, L van Dijk, J Timmerman, S Grosslight, R Walroth, K Püntener, ... | 3 | 2022 |
Development of a First-Generation Stereocontrolled Manufacturing Process of TRPA1 Inhibitor GDC-6599 AY Hong, KA Piechowicz, JC Timmerman, H Zhang, C Molinaro, ... Organic Process Research & Development, 2024 | 1 | 2024 |
Practical Synthesis of Reactive Immuno-PET Linker-Chelator (1R,2R)-RESCA-TFP N Wong, E Zhao, J Bao, SG Koenig, C Molinaro, JC Timmerman, H Zhang, ... Organic Process Research & Development 27 (7), 1400-1405, 2023 | 1 | 2023 |
Synthesis of quinazoline compounds NK Lim, J Shen, LE Sirois, JC Timmerman, E Trachsel, NA White, J Xu, ... US Patent App. 17/398,345, 2022 | 1 | 2022 |
anti-1′, 6′, 7′, 8′, 9′, 14′, 15′, 16′-Octachlorodispiro [1, 3-dioxolane-2, 17′-pentacyclo [12.2. 1.16, 9.02, 13.05, 10] octadecane-18′, 2′′-1, 3-dioxolane]-7′, 15 … ME Tenbusch, MD Brooker, JC Timmerman, DS Jones, M Etzkorn Acta Crystallographica Section E: Structure Reports Online 66 (8), o1882-o1882, 2010 | 1 | 2010 |
Process for synthesis of quinazoline compounds L Rene, NK Lim, RC Meier, UJ Orcel, J Sedelmeier, J Shen, LE Sirois, ... US Patent 12,071,422, 2024 | | 2024 |