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Thomas M. Burke
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Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis
R Chakraborty, TM Burke, OA Hampton, DJ Zinn, KPH Lim, H Abhyankar, ...
Blood, The Journal of the American Society of Hematology 128 (21), 2533-2537, 2016
1582016
CNS Langerhans cell histiocytosis: common hematopoietic origin for LCH‐associated neurodegeneration and mass lesions
KL McClain, J Picarsic, R Chakraborty, D Zinn, H Lin, H Abhyankar, ...
Cancer 124 (12), 2607-2620, 2018
1132018
A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease
KL Graham, JV Zhang, S Lewén, TM Burke, T Dang, M Zoudilova, ...
PloS one 9 (12), e112925, 2014
732014
A chimeric antibody against ACKR3/CXCR7 in combination with TMZ activates immune responses and extends survival in mouse GBM models
N Salazar, JC Carlson, K Huang, Y Zheng, C Oderup, J Gross, AD Jang, ...
Molecular Therapy 26 (5), 1354-1365, 2018
572018
Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH
A Sengal, J Velazquez, M Hahne, TM Burke, H Abhyankar, R Reyes, ...
Blood, The Journal of the American Society of Hematology 137 (13), 1777-1791, 2021
352021
Circulating CD1c+ myeloid dendritic cells are potential precursors to LCH lesion CD1a+CD207+ cells
KPH Lim, P Milne, M Poidinger, K Duan, H Lin, N McGovern, H Abhyankar, ...
Blood advances 4 (1), 87-99, 2020
332020
Robust expansion of dendritic cells in vivo by hydrodynamic FLT3L-FC gene transfer
H Tu, TM Burke, C Oderup, K Huang, K Wong, S Lewén, M LaJevic, ...
Journal of immunological methods 413, 69-73, 2014
122014
Anti TNF-α therapy in patients with relapsed and refractory Langerhans cell histiocytosis: a phase II study
A Flores Legarreta, O Eckstein, TM Burke, KL McClain
Pediatric Hematology and Oncology 35 (5-6), 362-368, 2018
72018
Use of the Seraph® 100 Microbind® Affinity Blood Filter in an adolescent patient with disseminated adenoviral disease
SM David S Li, Thomas M Burke, Jodi M Smith, Robyn C Reed, Daryl M Okamura
Pediatr Nephrol, 2023
4*2023
BRAF-V600E in Peripheral Mononuclear Cells and Microglia-like Brain Cells Suggest Hematopoietic Origin of Langerhans Cell Histiocytosis-Associated Neurodegeneration
D Zinn, J Picarsic, R Chakraborty, H Lin, H Abhyankar, B Scull, A Shih, ...
Blood 130, 2930, 2017
12017
Elevated CSF osteopontin and peripheral blood cells with braf mutations in patients with langerhans cell histiocytosis-associated neurodegeneration
D Zinn, J Picarsic, R Chakraborty, H Lin, H Abhyankar, B Scull, A Shih, ...
PEDIATRIC BLOOD & CANCER 63, S37-S38, 2016
12016
Use of the Seraph® 100 Microbind® Affinity Blood Filter in an Adolescent Patient with Disseminated Adenoviral Disease: SA-PO382
DS Li, TM Burke, JM Smith, DM Okamura, S Menon
Journal of the American Society of Nephrology 34 (11S), 828, 2023
2023
LACK OF RESPONSES TO BLOCKING TUMOR NECROSIS FACTOR ALPHA IN LANGERHANS CELL HISTIOCYTOSIS LESIONS IN PATIENTS AND MICE
T Burke, B Scull, H Abhyankar, O Eckstein, A Grom, K McClain, C Allen
PEDIATRIC BLOOD & CANCER 67, S5-S5, 2020
2020
Blocking MAPK Activation and Immune Checkpoints Reverse Immune Dysfunction and Reduce Disease in a Mouse Model of LCH
A Sengal, M Hahne, J Velasquez, H Abhyankar, T Burke, W Olea, ...
Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019
2019
CNS LANGERHANS CELL HISTIOCYTOSIS: COMMON HEMATOPOIETIC ORIGIN FOR LCH-ASSOCIATED NEURODEGENERATION AND MASS LESIONS
K McClain, J Picarsic, R Chakraborty, D Zinn, H Lin, H Abhyankar, B Scull, ...
PEDIATRIC BLOOD & CANCER 66, S30-S30, 2019
2019
CELL-SPECIFIC GENE EXPRESSION IN LANGERHANS CELL HISTIOCYTOSIS REVEALS DISTINCT PROFILES IN LESION CD207+ CELLS BASED ON BRAFV600E MUTATION
H Lin, KPH Lim, H Abhyankar, R Chakraborty, B Scull, O Eckstein, D Zinn, ...
PEDIATRIC BLOOD & CANCER 66, S25-S25, 2019
2019
EVALUATING ANTI-TNF-ALPHA THERAPY IN PATIENTS WITH RELAPSED AND REFRACTORY LANGERHANS CELL HISTIOCYTOSIS
T Burke, A Legarreta, H Lin, B Scull, O Eckstein, K McClain, C Allen
PEDIATRIC BLOOD & CANCER 66, S2-S3, 2019
2019
Evaluating Anti-TNF-Alpha Therapy in Patients with Relapsed and Refractory Langerhans Cell Histiocytosis
T Burke, A Legarreta, H Lin, B Scull, OS Eckstein, KL McClain, CE Allen
Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018
2018
Hematopoietic Origin and Targets for Therapy in CNS Langerhans Cell Histiocytosis: BRAF-V600E in Blood and Brain and Response to BRAF Inhibition Suggest Hematopoeitic Origin of …
O Eckstein, K McClain, J Picarsic, R Chakraborty, H Lin, H Abhyankar, ...
PEDIATRIC BLOOD & CANCER 64, S6-S6, 2017
2017
Identification of Novel BRAF Alterations in LCH Using an Integrated Genomic Pipeline
T Burke, R Chakraborty, O Hampton, D Zinn, B Scull, H Abhyankar, ...
PEDIATRIC BLOOD & CANCER 63, S13-S14, 2016
2016
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