Phenformin enhances the therapeutic benefit of BRAFV600E inhibition in melanoma P Yuan, K Ito, R Perez-Lorenzo, C Del Guzzo, JH Lee, CH Shen, ... Proceedings of the National Academy of Sciences 110 (45), 18226-18231, 2013 | 221 | 2013 |
HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression B Philip, K Ito, R Moreno-Sánchez, SJ Ralph Carcinogenesis 34 (8), 1699-1707, 2013 | 174 | 2013 |
Galectin-1 as a potent target for cancer therapy: role in the tumor microenvironment K Ito, K Stannard, E Gabutero, AM Clark, SY Neo, S Onturk, H Blanchard, ... Cancer and Metastasis Reviews 31, 763-778, 2012 | 152 | 2012 |
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model KA Stannard, PM Collins, K Ito, EM Sullivan, SA Scott, E Gabutero, ... Cancer letters 299 (2), 95-110, 2010 | 110 | 2010 |
Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress K Ito, SA Scott, S Cutler, LF Dong, J Neuzil, H Blanchard, SJ Ralph Angiogenesis 14, 293-307, 2011 | 109 | 2011 |
A polysaccharide extracted from Grifola frondosa enhances the anti-tumor activity of bone marrow-derived dendritic cell-based immunotherapy against murine … Y Masuda, K Ito, M Konishi, H Nanba Cancer immunology, immunotherapy 59, 1531-1541, 2010 | 96 | 2010 |
Inhibiting galectin-1 reduces murine lung metastasis with increased CD4+ and CD8+ T cells and reduced cancer cell adherence K Ito, SJ Ralph Clinical & experimental metastasis 29, 561-572, 2012 | 87 | 2012 |
Cross-species malaria immunity induced by chemically attenuated parasites MF Good, JM Reiman, IB Rodriguez, K Ito, SK Yanow, IM El-Deeb, ... The Journal of clinical investigation 123 (8), 3353-3362, 2013 | 84 | 2013 |
Characterization and antitumor effect of a novel polysaccharide from Grifola frondosa Y Masuda, A Matsumoto, T Toida, T Oikawa, K Ito, H Nanba Journal of Agricultural and Food Chemistry 57 (21), 10143-10149, 2009 | 75 | 2009 |
PTK6 inhibition suppresses metastases of triple negative breast cancer via Snail-dependent E-cadherin regulation K Ito, SH Park, A Nayak, JH Byerly, HY Irie Cancer Research, canres. 3445.2016, 2016 | 56 | 2016 |
Maitake beta-glucan enhances granulopoiesis and mobilization of granulocytes by increasing G-CSF production and modulating CXCR4/SDF-1 expression K Ito, Y Masuda, Y Yamasaki, Y Yokota, H Nanba International Immunopharmacology 9 (10), 1189-1196, 2009 | 48 | 2009 |
PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2+ breast cancer cells by inducing Bim SH Park, K Ito, W Olcott, I Katsyv, G Halstead-Nussloch, HY Irie Breast Cancer Research 17, 1-13, 2015 | 40 | 2015 |
Inferred miRNA activity identifies miRNA-mediated regulatory networks underlying multiple cancers E Lee, K Ito, Y Zhao, EE Schadt, HY Irie, J Zhu Bioinformatics 32 (1), 96-105, 2016 | 35 | 2016 |
PRKCQ promotes oncogenic growth and anoikis resistance of a subset of triple-negative breast cancer cells J Byerly, G Halstead-Nussloch, K Ito, I Katsyv, HY Irie Breast Cancer Research 18 (1), 1-11, 2016 | 33 | 2016 |
PTK6 regulates growth and survival of endocrine therapy-resistant ER+ breast cancer cells K Ito, SH Park, I Katsyv, W Zhang, C De Angelis, R Schiff, HY Irie NPJ Breast Cancer 3 (1), 45, 2017 | 26 | 2017 |
Induction of immunity following vaccination with a chemically attenuated malaria vaccine correlates with persistent antigenic stimulation JM Reiman, S Kumar, IB Rodriguez, S Gnidehou, K Ito, DI Stanisic, M Lee, ... Clinical & Translational Immunology 7 (4), e1015, 2018 | 6 | 2018 |
PRMT5 inhibition regulates alternative splicing and DNA damage repair pathways in SF3B1 R625G expressing uveal melanoma cells K Ito, V Thodima, J Carter, N Bhagwat, M Sivakumar, A Grego, J Rager, ... Cancer Research 81 (13_Supplement), 1137-1137, 2021 | 5 | 2021 |
PRMT5 inhibition downregulates MYB and NOTCH1 signaling, key molecular drivers of adenoid cystic carcinoma J Carter, K Ito, V Thodima, N Bhagwat, J Rager, NS Burr, J Kaufman, ... Cancer Res 81, 1138, 2021 | 3 | 2021 |
Preclinical characterization of PRT3789, a potent and selective SMARCA2 targeted degrader M Hulse, A Agarwal, M Wang, J Carter, M Sivakumar, B Vidal, J Brown, ... Cancer Research 82 (12), 2022 | 2 | 2022 |
Potent SMARCA2 targeted degraders induce genetic synthetic lethality in SMARCA4 deleted cancer K Ito, A Agarwal, P Pitis, M Wang, J Carter, M Cowart, C Dai, ... Cancer Research 81 (13_Supplement), 1139-1139, 2021 | 2 | 2021 |