Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis N Singh, A Gurav, S Sivaprakasam, E Brady, R Padia, H Shi, ... Immunity 40 (1), 128-139, 2014 | 2067 | 2014 |
Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis S Sivaprakasam, PD Prasad, N Singh Pharmacology & therapeutics 164, 144-151, 2016 | 494 | 2016 |
Short‐Chain Fatty Acid Transporters: Role in Colonic Homeostasis S Sivaprakasam, YD Bhutia, S Yang, V Ganapathy Comprehensive Physiology 8 (1), 299-314, 2017 | 251 | 2017 |
The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment TP Brown, P Bhattacharjee, S Ramachandran, S Sivaprakasam, B Ristic, ... Oncogene 39 (16), 3292-3304, 2020 | 174 | 2020 |
Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer … A Gurav, S Sivaprakasam, YD Bhutia, T Boettger, N Singh, V Ganapathy Biochemical journal 469 (2), 267-278, 2015 | 155 | 2015 |
RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis M Zhang, X Zhu, Y Zhang, Y Cai, J Chen, S Sivaprakasam, A Gurav, W Pi, ... Cell Death & Differentiation 22 (12), 1922-1934, 2015 | 145 | 2015 |
UFBP1, a key component of the Ufm1 conjugation system, is essential for ufmylation-mediated regulation of erythroid development Y Cai, W Pi, S Sivaprakasam, X Zhu, M Zhang, J Chen, L Makala, C Lu, ... PLoS genetics 11 (11), e1005643, 2015 | 139 | 2015 |
An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis S Sivaprakasam, A Gurav, AV Paschall, GL Coe, K Chaudhary, Y Cai, ... Oncogenesis 5 (6), e238-e238, 2016 | 129 | 2016 |
Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR H Zhu, B Bhatt, S Sivaprakasam, Y Cai, S Liu, SK Kodeboyina, N Patel, ... Nature communications 10 (1), 1084, 2019 | 87 | 2019 |
Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB0,+ to deliver chemotherapeutic agents for colon cancer therapy L Kou, Q Yao, S Sivaprakasam, Q Luo, Y Sun, Q Fu, Z He, J Sun, ... Drug Delivery 24 (1), 1338-1349, 2017 | 75 | 2017 |
Cell-surface and nuclear receptors in the colon as targets for bacterial metabolites and its relevance to colon health S Sivaprakasam, YD Bhutia, S Ramachandran, V Ganapathy Nutrients 9 (8), 856, 2017 | 72 | 2017 |
Gpr109a limits microbiota-induced IL-23 production to constrain ILC3-mediated colonic inflammation B Bhatt, P Zeng, H Zhu, S Sivaprakasam, S Li, H Xiao, L Dong, P Shiao, ... The Journal of Immunology 200 (8), 2905-2914, 2018 | 66 | 2018 |
Anti-angiogenic potential of CoenzymeQ10, riboflavin and niacin in breast cancer patients undergoing tamoxifen therapy VG Premkumar, S Yuvaraj, S Sathish, P Shanthi, P Sachdanandam Vascular pharmacology 48 (4-6), 191-201, 2008 | 63 | 2008 |
SLC6A14, a Na+/Cl−-coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling MOF Sikder, S Sivaprakasam, TP Brown, M Thangaraju, YD Bhutia, ... Biochemical Journal 477 (8), 1409-1425, 2020 | 42 | 2020 |
Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer YD Bhutia, J Ogura, PJ Grippo, C Torres, T Sato, M Wachtel, ... Asian journal of pharmaceutical sciences 15 (2), 237-251, 2020 | 35 | 2020 |
Gut microbiome and colon cancer: Role of bacterial metabolites and their molecular targets in the host YD Bhutia, J Ogura, S Sivaprakasam, V Ganapathy Current colorectal cancer reports 13, 111-118, 2017 | 30 | 2017 |
Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood–brain barrier JJ Kopel, YD Bhutia, S Sivaprakasam, V Ganapathy Biochemical Journal 478 (3), 463-486, 2021 | 24 | 2021 |
Hereditary hemochromatosis promotes colitis and colon cancer and causes bacterial dysbiosis in mice S Sivaprakasam, B Ristic, N Mudaliar, AN Hamood, J Colmer-Hamood, ... Biochemical Journal 477 (19), 3867-3883, 2020 | 21 | 2020 |
SLC6A14 deficiency is linked to obesity, fatty liver, and metabolic syndrome but only under conditions of a high-fat diet S Sivaprakasam, MOF Sikder, L Ramalingam, G Kaur, JM Dufour, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1867 (5), 166087, 2021 | 19 | 2021 |
Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY) K Higuchi, JJ Kopel, S Sivaprakasam, V Jaramillo-Martinez, RB Sutton, ... Biochemical Journal 477 (21), 4149-4165, 2020 | 16 | 2020 |