Fragment-based screening of a natural product library against 62 potential malaria drug targets employing native mass spectrometry H Vu, L Pedro, T Mak, B McCormick, J Rowley, M Liu, A Di Capua, ... ACS infectious diseases 4 (4), 431-444, 2018 | 61 | 2018 |
Novel analgesic/anti-inflammatory agents: 1, 5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors M Anzini, A Di Capua, S Valenti, S Brogi, M Rovini, G Giuliani, A Cappelli, ... Journal of medicinal chemistry 56 (8), 3191-3206, 2013 | 46 | 2013 |
In vitro effects of VA441, a new selective cyclooxygenase-2 inhibitor, on human osteoarthritic chondrocytes exposed to IL-1β A Fioravanti, L Tinti, NA Pascarelli, A Di Capua, A Lamboglia, A Cappelli, ... Journal of pharmacological sciences 120 (1), 6-14, 2012 | 34 | 2012 |
Synthesis and biological evaluation of fluorinated 1, 5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity A Di Capua, C Sticozzi, S Brogi, M Brindisi, A Cappelli, L Sautebin, ... European journal of medicinal chemistry 109, 99-106, 2016 | 33 | 2016 |
Chondroprotective effect of three different classes of anti-inflammatory agents on human osteoarthritic chondrocytes exposed to IL-1β S Cheleschi, NA Pascarelli, G Valacchi, A Di Capua, M Biava, G Belmonte, ... International Immunopharmacology 28 (1), 794-801, 2015 | 31 | 2015 |
Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors M Biava, C Battilocchio, G Poce, S Alfonso, S Consalvi, A Di Capua, ... Bioorganic & medicinal chemistry 22 (2), 772-786, 2014 | 28 | 2014 |
Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors S Consalvi, S Alfonso, A Di Capua, G Poce, A Pirolli, M Sabatino, ... Bioorganic & Medicinal Chemistry 23 (4), 810-820, 2015 | 27 | 2015 |
The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure … A Martelli, L Testai, M Anzini, A Cappelli, A Di Capua, M Biava, G Poce, ... Pharmacological research 78, 1-9, 2013 | 25 | 2013 |
Antiproliferative effect of two novel COX-2 inhibitors on human keratinocytes C Sticozzi, G Belmonte, F Cervellati, A Di Capua, E Maioli, A Cappelli, ... European Journal of Pharmaceutical Sciences 49 (2), 133-141, 2013 | 25 | 2013 |
Discovery of a Natural Product That Binds to the Mycobacterium tuberculosis Protein Rv1466 Using Native Mass Spectrometry AR Elnaas, D Grice, J Han, Y Feng, AD Capua, T Mak, JA Laureanti, ... Molecules 25 (10), 2384, 2020 | 24 | 2020 |
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1, 5-diarylpyrrol-3-substituted scaffold A Reale, S Brogi, A Chelini, M Paolino, A Di Capua, G Giuliani, A Cappelli, ... Bioorganic & Medicinal Chemistry 27 (19), 115045, 2019 | 24 | 2019 |
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents A Mancini, A Chelini, A Di Capua, L Castelli, S Brogi, M Paolino, ... European journal of medicinal chemistry 126, 614-630, 2017 | 24 | 2017 |
Synthesis and biological evaluation of novel neuroprotective pyridazine derivatives as excitatory amino acid transporter 2 (EAAT2) activators A Chelini, S Brogi, M Paolino, A Di Capua, A Cappelli, G Giorgi, M Farzad, ... Journal of Medicinal Chemistry 60 (12), 5216-5221, 2017 | 19 | 2017 |
An overview of methods for L-dopa extraction and analytical determination in plant matrices C Tesoro, F Lelario, R Ciriello, G Bianco, A Di Capua, MA Acquavia Separations 9 (8), 224, 2022 | 18 | 2022 |
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors A Cappelli, M Anzini, F Castriconi, G Grisci, M Paolino, C Braile, S Valenti, ... Journal of Medicinal Chemistry 59 (7), 3353-3372, 2016 | 18 | 2016 |
Synthesis of trifluoromethyl-substituted pyrazolo [4, 3-c] pyridines–sequential versus multicomponent reaction approach B Palka, A Di Capua, M Anzini, G Vilkauskaité, A Šačkus, W Holzer Beilstein Journal of Organic Chemistry 10 (1), 1759-1764, 2014 | 15 | 2014 |
A phenotarget approach for identifying an alkaloid interacting with the tuberculosis protein Rv1466 Y Xie, Y Feng, A Di Capua, T Mak, GW Buchko, PJ Myler, M Liu, RJ Quinn Marine Drugs 18 (3), 149, 2020 | 14 | 2020 |
Integrated use of biochemical, native mass spectrometry, computational, and genome-editing methods to elucidate the mechanism of a Salmonella deglycase A Sengupta, J Wu, JT Seffernick, A Sabag-Daigle, N Thomsen, TH Chen, ... Journal of molecular biology 431 (22), 4497-4513, 2019 | 14 | 2019 |
Enantioresolution and stereochemical characterization of two chiral sulfoxides endowed with COX‐2 inhibitory activity R Sardella, F Ianni, A Di Michele, A Di Capua, A Carotti, M Anzini, ... Chirality 29 (9), 536-540, 2017 | 14 | 2017 |
Synthesis of Imidazo [1, 5-a] quinolines via Metal-Free Oxidative Amination of sp3 C–H Bonds H Liu, X Wang, C Ma Synthesis 50 (14), 2761-2767, 2018 | 13 | 2018 |