Type I interferon in chronic virus infection and cancer LM Snell, TL McGaha, DG Brooks Trends in immunology 38 (8), 542-557, 2017 | 423 | 2017 |
T‐cell intrinsic effects of GITR and 4‐1BB during viral infection and cancer immunotherapy LM Snell, GHY Lin, AJ McPherson, TJ Moraes, TH Watts Immunological reviews 244 (1), 197-217, 2011 | 167 | 2011 |
CD8 T cell-intrinsic GITR is required for T cell clonal expansion and mouse survival following severe influenza infection LM Snell, AJ McPherson, GHY Lin, S Sakaguchi, PP Pandolfi, C Riccardi, ... The Journal of Immunology 185 (12), 7223-7234, 2010 | 130 | 2010 |
Opposing roles for TRAF1 in the alternative versus classical NF-κB pathway in T cells AJ McPherson, LM Snell, TW Mak, TH Watts Journal of Biological Chemistry 287 (27), 23010-23019, 2012 | 115 | 2012 |
Endogenous 4-1BB ligand plays a critical role in protection from influenza-induced disease GHY Lin, BJ Sedgmen, TJ Moraes, LM Snell, DJ Topham, TH Watts The Journal of Immunology 182 (2), 934-947, 2009 | 109 | 2009 |
CD8+ T cell priming in established chronic viral infection preferentially directs differentiation of memory-like cells for sustained immunity LM Snell, BL MacLeod, JC Law, I Osokine, HJ Elsaesser, K Hezaveh, ... Immunity 49 (4), 678-694. e5, 2018 | 108 | 2018 |
A critical role for TNF receptor-associated factor 1 and Bim down-regulation in CD8 memory T cell survival L Sabbagh, CC Srokowski, G Pulle, LM Snell, BJ Sedgmen, Y Liu, ... Proceedings of the National Academy of Sciences 103 (49), 18703-18708, 2006 | 108 | 2006 |
Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection I Osokine, LM Snell, CR Cunningham, DH Yamada, EB Wilson, ... Proceedings of the National Academy of Sciences 111 (20), 7409-7414, 2014 | 103 | 2014 |
Networking at the level of host immunity: immune cell interactions during persistent viral infections CT Ng, LM Snell, DG Brooks, MBA Oldstone Cell host & microbe 13 (6), 652-664, 2013 | 103 | 2013 |
Overcoming CD4 Th1 cell fate restrictions to sustain antiviral CD8 T cells and control persistent virus infection LM Snell, I Osokine, DH Yamada, JR De la Fuente, HJ Elsaesser, ... Cell reports 16 (12), 3286-3296, 2016 | 102 | 2016 |
TNF family ligands define niches for T cell memory L Sabbagh, LM Snell, TH Watts Trends in immunology 28 (8), 333-339, 2007 | 100 | 2007 |
Type I and type II interferon coordinately regulate suppressive dendritic cell fate and function during viral persistence CR Cunningham, A Champhekar, MV Tullius, BJ Dillon, A Zhen, ... PloS pathogens 12 (1), e1005356, 2016 | 78 | 2016 |
New insights into type I interferon and the immunopathogenesis of persistent viral infections LM Snell, DG Brooks Current opinion in immunology 34, 91-98, 2015 | 58 | 2015 |
The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity S Lukhele, D Abd Rabbo, M Guo, J Shen, HJ Elsaesser, R Quevedo, ... Immunity 55 (12), 2369-2385. e10, 2022 | 54 | 2022 |
GITR-dependent regulation of 4-1BB expression: implications for T cell memory and anti–4-1BB–induced pathology GHY Lin, LM Snell, ME Wortzman, DL Clouthier, TH Watts The Journal of Immunology 190 (9), 4627-4639, 2013 | 48 | 2013 |
IL-15–Dependent Upregulation of GITR on CD8 Memory Phenotype T Cells in the Bone Marrow Relative to Spleen and Lymph Node Suggests the Bone Marrow as a Site of Superior … LM Snell, GHY Lin, TH Watts The Journal of Immunology 188 (12), 5915-5923, 2012 | 48 | 2012 |
Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection LM Snell, W Xu, D Abd-Rabbo, G Boukhaled, M Guo, BL Macleod, ... Nature immunology 22 (12), 1524-1537, 2021 | 35 | 2021 |
Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection W Xu, LM Snell, M Guo, G Boukhaled, BL Macleod, M Li, MV Tullius, ... Immunity 54 (3), 526-541. e7, 2021 | 34 | 2021 |
Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection HJ Elsaesser, M Mohtashami, I Osokine, LM Snell, CR Cunningham, ... Proceedings of the National Academy of Sciences 117 (10), 5420-5429, 2020 | 29 | 2020 |
Contribution of 4–1 BB L on radioresistant cells in providing survival signals through 4–1 BB expressed on CD 8+ memory T cells in the bone marrow GHY Lin, F Edele, AN Mbanwi, ME Wortzman, LM Snell, M Vidric, K Roth, ... European Journal of Immunology 42 (11), 2861-2874, 2012 | 25 | 2012 |