Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants HS Hwang, FR Nitu, Y Yang, K Walweel, L Pereira, CN Johnson, ... Circulation research 114 (7), 1114-1124, 2014 | 159 | 2014 |
Mapping the interaction surface of a membrane protein: unveiling the conformational switch of phospholamban in calcium pump regulation J Zamoon, F Nitu, C Karim, DD Thomas, G Veglia Proceedings of the National Academy of Sciences 102 (13), 4747-4752, 2005 | 144 | 2005 |
Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks N Gomez-Hurtado, NJ Boczek, DO Kryshtal, CN Johnson, J Sun, FR Nitu, ... Circulation: Arrhythmia and Electrophysiology 9 (8), e004161, 2016 | 106 | 2016 |
FRET-based mapping of calmodulin bound to the RyR1 Ca2+ release channel RL Cornea, F Nitu, S Gruber, K Kohler, M Satzer, DD Thomas, BR Fruen Proceedings of the National Academy of Sciences 106 (15), 6128-6133, 2009 | 63 | 2009 |
High-throughput screens to discover small-molecule modulators of ryanodine receptor calcium release channels RT Rebbeck, MM Essawy, FR Nitu, BD Grant, GD Gillispie, DD Thomas, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (2), 176-186, 2017 | 62 | 2017 |
Mapping the ryanodine receptor FK506-binding protein subunit using fluorescence resonance energy transfer RL Cornea, FR Nitu, M Samso, DD Thomas, BR Fruen Journal of Biological Chemistry 285 (25), 19219-19226, 2010 | 57 | 2010 |
Antifungal properties of lectin and new chitinases from potato tubers. O Gozia, J Ciopraga, T Bentia, M Lungu, I Zamfirescu, R Tudor, ... Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie 316 …, 1993 | 47 | 1993 |
FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel T Guo, BR Fruen, FR Nitu, TD Nguyen, Y Yang, RL Cornea, DM Bers Biophysical journal 101 (9), 2170-2177, 2011 | 45 | 2011 |
Impact of methionine oxidation on calmodulin structural dynamics MR McCarthy, AR Thompson, F Nitu, RJ Moen, MJ Olenek, JC Klein, ... Biochemical and biophysical research communications 456 (2), 567-572, 2015 | 44 | 2015 |
S100A1 protein does not compete with calmodulin for ryanodine receptor binding but structurally alters the ryanodine receptor· calmodulin complex RT Rebbeck, FR Nitu, D Rohde, P Most, DM Bers, DD Thomas, ... Journal of Biological Chemistry 291 (30), 15896-15907, 2016 | 39 | 2016 |
In cardiomyocytes, binding of unzipping peptide activates ryanodine receptor 2 and reciprocally inhibits calmodulin binding T Oda, Y Yang, FR Nitu, B Svensson, X Lu, BR Fruen, RL Cornea, ... Circulation research 112 (3), 487-497, 2013 | 31 | 2013 |
Direct detection of calmodulin tuning by ryanodine receptor channel targets using a Ca2+-sensitive acrylodan-labeled calmodulin BR Fruen, EM Balog, J Schafer, FR Nitu, DD Thomas, L Razvan Biochemistry 44 (1), 278-284, 2005 | 28 | 2005 |
N-terminal and central segments of the type 1 ryanodine receptor mediate its interaction with FK506-binding proteins T Girgenrath, M Mahalingam, B Svensson, FR Nitu, RL Cornea, ... Journal of Biological Chemistry 288 (22), 16073-16084, 2013 | 26 | 2013 |
Accurate quantitation of phospholamban phosphorylation by immunoblot NA Ablorh, T Miller, F Nitu, SJ Gruber, C Karim, DD Thomas Analytical biochemistry 425 (1), 68-75, 2012 | 26 | 2012 |
FRET-based trilateration of probes bound within functional ryanodine receptors B Svensson, T Oda, FR Nitu, Y Yang, I Cornea, Y Chen-Izu, ... Biophysical journal 107 (9), 2037-2048, 2014 | 14 | 2014 |
Label-free homogeneous microRNA detection in cell culture medium based on graphene oxide and specific fluorescence quenching FR Nitu, L Savu, S Muraru, I Stoian, M Ionită Nanomaterials 11 (2), 368, 2021 | 9 | 2021 |
Oligonucleotide detection and optical measurement with graphene oxide in the presence of bovine serum albumin enabled by use of surfactants and salts FR Nitu, JS Burns, M Ionită Coatings 10 (4), 420, 2020 | 8 | 2020 |
Insulin-dependent rescue from cardiogenic shock is not mediated by phospholamban phosphorylation NA Ablorh, F Nitu, K Engebretsen, DD Thomas, JS Holger Clinical Toxicology 47 (4), 296-302, 2009 | 6 | 2009 |
Graphene Oxide/Nitrocellulose Non-Covalent Hybrid as Solid Phase for Oligo-DNA Extraction from Complex Medium GA Toader, FR Nitu, M Ionita Molecules 28 (12), 4599, 2023 | 4 | 2023 |
Recent Efforts and Milestones for Simulating Nucleic Acid FRET Experiments through Computational Methods S Muraru, S Muraru, FR Nitu, M Ionita Journal of Chemical Information and Modeling 62 (2), 232-239, 2022 | 3 | 2022 |