Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies D Wrapp, D De Vlieger, KS Corbett, GM Torres, N Wang, W Van Breedam, ... Cell 181 (5), 1004-1015. e15, 2020 | 684 | 2020 |
Structural basis of the proinflammatory signaling complex mediated by TSLP K Verstraete, L Van Schie, L Vyncke, Y Bloch, J Tavernier, E Pauwels, ... Nature structural & molecular biology 21 (4), 375-382, 2014 | 56 | 2014 |
An affinity-enhanced, broadly neutralizing heavy chain–only antibody protects against SARS-CoV-2 infection in animal models B Schepens, L van Schie, W Nerinckx, K Roose, W Van Breedam, ... Science Translational Medicine 13 (621), eabi7826, 2021 | 54 | 2021 |
VIB-CMB COVID-19 Response Team D Wrapp, D De Vlieger, KS Corbett, GM Torres, N Wang, W Van Breedam, ... Structural basis for potent neutralization of betacoronaviruses by single …, 2020 | 50 | 2020 |
A potential role for fructosamine-3-kinase in cataract treatment S De Bruyne, L van Schie, J Himpe, F De Somer, I Everaert, W Derave, ... International journal of molecular sciences 22 (8), 3841, 2021 | 17 | 2021 |
VIB-CMB COVID-19 Response Team, Hoffmann M et al (2020a) Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies D Wrapp, D De Vlieger, KS Corbett, GM Torres, N Wang, W Van Breedam, ... Cell 181, 1004-1015, 0 | 14 | |
Exploration of synergistic action of cell wall-degrading enzymes against Mycobacterium tuberculosis L van Schie, K Borgers, G Michielsen, E Plets, M Vuylsteke, P Tiels, ... Antimicrobial Agents and Chemotherapy 65 (10), 10.1128/aac. 00659-21, 2021 | 12 | 2021 |
Development of a counterselectable transposon to create markerless knockouts from an 18,432-clone ordered Mycobacterium bovis Bacillus Calmette-Guerin mutant resource K Borgers, K Vandewalle, A Van Hecke, G Michielsen, E Plets, ... Msystems 5 (4), 10.1128/msystems. 00180-20, 2020 | 8 | 2020 |
OPENPichia: licence-free Komagataella phaffii chassis strains and toolkit for protein expression K Claes, D Van Herpe, R Vanluchene, C Roels, B Van Moer, E Wyseure, ... Nature Microbiology 9 (3), 864-876, 2024 | 7 | 2024 |
A simple colorimetric assay for measuring fructosamine 3 kinase activity JC Cikomola, AS Kishabongo, K Vandepoele, M De Mulder, ... Clinical Chemistry and Laboratory Medicine (CCLM) 55 (1), 154-159, 2017 | 5 | 2017 |
GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery L van Schie, W Van Breedam, C Roels, B Schepens, M Frank, ... MAbs 15 (1), 2210709, 2023 | 4 | 2023 |
OPENPichia: building a free-to-operate Komagataella phaffii protein expression toolkit D Van Herpe, R Vanluchene, K Vandewalle, S Vanmarcke, E Wyseure, ... bioRxiv, 2022.12. 13.519130, 2022 | 4 | 2022 |
Drug development of an affinity enhanced, broadly neutralizing heavy chain-only antibody that restricts SARS-CoV-2 in rodents B Schepens, L van Schie, W Nerinckx, K Roose, W Van Breedam, ... BioRxiv, 2021.03. 08.433449, 2021 | 4 | 2021 |
Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike S De Cae, I Van Molle, L van Schie, SR Shoemaker, J Deckers, N Debeuf, ... bioRxiv, 2023.03. 10.531533, 2023 | 3 | 2023 |
Yeast-produced fructosamine-3-kinase retains mobility after ex vivo intravitreal injection in human and bovine eyes as determined by Fluorescence Correlation Spectroscopy AK Minnaert, L van Schie, H Grootaert, J Himpe, S Devos, W Weyts, ... International Journal of Pharmaceutics 621, 121772, 2022 | 2 | 2022 |
GlycoVHH: introducing N-glycans on the camelid VHH antibody scaffold-Optimal sites and use for macrophage delivery L van Schie, W Van Breedam, C Roels, B Schepens, M Frank, ... BioRXiv, 2022.04. 25.489312, 2022 | 2 | 2022 |
Use of a counterselectable transposon to create markerless knockouts from a 18,432-clone ordered M. bovis BCG mutant resource K Borgers, K Vandewalle, A Van Hecke, G Michielsen, E Plets, ... bioRxiv, 817007, 2019 | 2 | 2019 |
Corona virus binders B Schepens, X Saelens, N Callewaert, D De Vlieger, L Van Schie, ... US Patent App. 17/760,300, 2023 | 1 | 2023 |
Pan-specific corona virus binders B Schepens, L Van Schie, H Eeckhaut, W Nerinckx, D Fijalkowska, ... US Patent App. 18/559,915, 2024 | | 2024 |
Sarbecovirus binders X Saelens, D De Vlieger, I Rossey, DE Sieglinde, K Sedeyn, L Van Schie, ... US Patent App. 18/275,986, 2024 | | 2024 |