Whole-organism lineage tracing by combinatorial and cumulative genome editing A McKenna, GM Findlay, JA Gagnon, MS Horwitz, AF Schier, J Shendure Science 353 (6298), aaf7907, 2016 | 723 | 2016 |
Accurate classification of BRCA1 variants with saturation genome editing GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith, M Gasperini, ... Nature 562 (7726), 217-222, 2018 | 721 | 2018 |
Saturation editing of genomic regions by multiplex homology-directed repair GM Findlay, EA Boyle, RJ Hause, JC Klein, J Shendure Nature 513 (7516), 120-123, 2014 | 401 | 2014 |
Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex S Sharma, GM Findlay, HS Bandukwala, S Oberdoerffer, B Baust, Z Li, ... Proceedings of the National Academy of Sciences 108 (28), 11381-11386, 2011 | 313 | 2011 |
An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry S Sharma, A Quintana, GM Findlay, M Mettlen, B Baust, M Jain, R Nilsson, ... Nature 499 (7457), 238-242, 2013 | 245 | 2013 |
Genomic medicine–progress, pitfalls, and promise J Shendure, GM Findlay, MW Snyder Cell 177 (1), 45-57, 2019 | 211 | 2019 |
Multiplex homology-directed repair J Shendure, E Boyle, G Findlay US Patent App. 14/818,217, 2016 | 201 | 2016 |
CRISPR/Cas9-mediated scanning for regulatory elements required for HPRT1 expression via thousands of large, programmed genomic deletions M Gasperini, GM Findlay, A McKenna, JH Milbank, C Lee, MD Zhang, ... The American Journal of Human Genetics 101 (2), 192-205, 2017 | 148 | 2017 |
Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy F Aguet, S Upadhyayula, R Gaudin, Y Chou, E Cocucci, K He, BC Chen, ... Molecular biology of the cell 27 (22), 3418-3435, 2016 | 131 | 2016 |
Linking genome variants to disease: scalable approaches to test the functional impact of human mutations GM Findlay Human molecular genetics 30 (R2), R187-R197, 2021 | 39 | 2021 |
Systematic dissection of coding exons at single nucleotide resolution supports an additional role in cell-specific transcriptional regulation RY Birnbaum, RP Patwardhan, MJ Kim, GM Findlay, B Martin, J Zhao, ... PLoS Genetics 10 (10), e1004592, 2014 | 39 | 2014 |
spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content J De Jonghe, TS Kaminski, DB Morse, M Tabaka, AL Ellermann, ... Nature Communications 14 (1), 4788, 2023 | 15 | 2023 |
Concurrent genome and epigenome editing by CRISPR-mediated sequence replacement J Alexander, GM Findlay, M Kircher, J Shendure BMC biology 17, 1-13, 2019 | 12 | 2019 |
Genome sequencing of idiopathic pulmonary fibrosis in conjunction with a medical school human anatomy course A Kumar, M Dougherty, GM Findlay, M Geisheker, J Klein, J Lazar, ... PLoS One 9 (9), e106744, 2014 | 10 | 2014 |
Saturation Genome Editing Resolves the Functional Spectrum of Pathogenic VHL Alleles M Buckley, CM Kajba, N Forrester, C Terwagne, C Sawyer, ... bioRxiv, 2023.06. 10.542698, 2023 | 3 | 2023 |
High-throughput screening of human genetic variants by pooled prime editing M Herger, CM Kajba, M Buckley, A Cunha, M Strom, GM Findlay bioRxiv, 2024.04. 01.587366, 2024 | 1 | 2024 |
Reducing uncertainty in genetic testing with Saturation Genome Editing P Dace, GM Findlay Medizinische Genetik 34 (4), 297-304, 2022 | 1 | 2022 |
Systematically editing the human genome at scale G Findlay EUROPEAN JOURNAL OF HUMAN GENETICS 32, 82-82, 2024 | | 2024 |
High-throughput interrogation of genome function and cellular lineage G Findlay | | 2018 |
Evaluation of single nucleotide variants in exon 5 of BRCA1 using a redesigned Saturation Genome Editing assay P Dace, GM Findlay | | |