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Gregory M. Findlay
Gregory M. Findlay
在 crick.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Whole-organism lineage tracing by combinatorial and cumulative genome editing
A McKenna, GM Findlay, JA Gagnon, MS Horwitz, AF Schier, J Shendure
Science 353 (6298), aaf7907, 2016
7232016
Accurate classification of BRCA1 variants with saturation genome editing
GM Findlay, RM Daza, B Martin, MD Zhang, AP Leith, M Gasperini, ...
Nature 562 (7726), 217-222, 2018
7212018
Saturation editing of genomic regions by multiplex homology-directed repair
GM Findlay, EA Boyle, RJ Hause, JC Klein, J Shendure
Nature 513 (7516), 120-123, 2014
4012014
Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex
S Sharma, GM Findlay, HS Bandukwala, S Oberdoerffer, B Baust, Z Li, ...
Proceedings of the National Academy of Sciences 108 (28), 11381-11386, 2011
3132011
An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry
S Sharma, A Quintana, GM Findlay, M Mettlen, B Baust, M Jain, R Nilsson, ...
Nature 499 (7457), 238-242, 2013
2452013
Genomic medicine–progress, pitfalls, and promise
J Shendure, GM Findlay, MW Snyder
Cell 177 (1), 45-57, 2019
2112019
Multiplex homology-directed repair
J Shendure, E Boyle, G Findlay
US Patent App. 14/818,217, 2016
2012016
CRISPR/Cas9-mediated scanning for regulatory elements required for HPRT1 expression via thousands of large, programmed genomic deletions
M Gasperini, GM Findlay, A McKenna, JH Milbank, C Lee, MD Zhang, ...
The American Journal of Human Genetics 101 (2), 192-205, 2017
1482017
Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy
F Aguet, S Upadhyayula, R Gaudin, Y Chou, E Cocucci, K He, BC Chen, ...
Molecular biology of the cell 27 (22), 3418-3435, 2016
1312016
Linking genome variants to disease: scalable approaches to test the functional impact of human mutations
GM Findlay
Human molecular genetics 30 (R2), R187-R197, 2021
392021
Systematic dissection of coding exons at single nucleotide resolution supports an additional role in cell-specific transcriptional regulation
RY Birnbaum, RP Patwardhan, MJ Kim, GM Findlay, B Martin, J Zhao, ...
PLoS Genetics 10 (10), e1004592, 2014
392014
spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content
J De Jonghe, TS Kaminski, DB Morse, M Tabaka, AL Ellermann, ...
Nature Communications 14 (1), 4788, 2023
152023
Concurrent genome and epigenome editing by CRISPR-mediated sequence replacement
J Alexander, GM Findlay, M Kircher, J Shendure
BMC biology 17, 1-13, 2019
122019
Genome sequencing of idiopathic pulmonary fibrosis in conjunction with a medical school human anatomy course
A Kumar, M Dougherty, GM Findlay, M Geisheker, J Klein, J Lazar, ...
PLoS One 9 (9), e106744, 2014
102014
Saturation Genome Editing Resolves the Functional Spectrum of Pathogenic VHL Alleles
M Buckley, CM Kajba, N Forrester, C Terwagne, C Sawyer, ...
bioRxiv, 2023.06. 10.542698, 2023
32023
High-throughput screening of human genetic variants by pooled prime editing
M Herger, CM Kajba, M Buckley, A Cunha, M Strom, GM Findlay
bioRxiv, 2024.04. 01.587366, 2024
12024
Reducing uncertainty in genetic testing with Saturation Genome Editing
P Dace, GM Findlay
Medizinische Genetik 34 (4), 297-304, 2022
12022
Systematically editing the human genome at scale
G Findlay
EUROPEAN JOURNAL OF HUMAN GENETICS 32, 82-82, 2024
2024
High-throughput interrogation of genome function and cellular lineage
G Findlay
2018
Evaluation of single nucleotide variants in exon 5 of BRCA1 using a redesigned Saturation Genome Editing assay
P Dace, GM Findlay
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