| The transcription factor Nrf2 is a therapeutic target against brain inflammation NG Innamorato, AI Rojo, AJ García-Yagüe, M Yamamoto, ... The Journal of Immunology 181 (1), 680-689, 2008 | 549 | 2008 |
| Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes M Pajares, N Jiménez-Moreno, ÁJ García-Yagüe, M Escoll, ... Autophagy 12 (10), 1902-1916, 2016 | 351 | 2016 |
| Repurposing the NRF2 activator dimethyl fumarate as therapy against synucleinopathy in Parkinson's disease I Lastres-Becker, AJ García-Yagüe, RH Scannevin, MJ Casarejos, ... Antioxidants & redox signaling 25 (2), 61-77, 2016 | 256 | 2016 |
| Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy AI Rojo, M Pajares, AJ García-Yagüe, I Buendia, F Van Leuven, ... Redox biology 18, 173-180, 2018 | 87 | 2018 |
| Nuclear import and export signals control the subcellular localization of Nurr1 protein in response to oxidative stress ÁJ García-Yagüe, P Rada, AI Rojo, I Lastres-Becker, A Cuadrado Journal of Biological Chemistry 288 (8), 5506-5517, 2013 | 77 | 2013 |
| Cx3cr1‐deficiency exacerbates alpha‐synuclein‐A53T induced neuroinflammation and neurodegeneration in a mouse model of Parkinson's disease S Castro‐Sánchez, ÁJ García‐Yagüe, T López‐Royo, M Casarejos, ... Glia 66 (8), 1752-1762, 2018 | 59 | 2018 |
| CX3CR1-deficient microglia shows impaired signalling of the transcription factor NRF2: Implications in tauopathies S Castro-Sánchez, ÁJ García-Yagüe, S Kügler, I Lastres-Becker Redox biology 22, 101118, 2019 | 42 | 2019 |
| Role of MSK1 in the induction of NF-κB by the chemokine CX3CL1 in microglial cells M Galán-Ganga, ÁJ García-Yagüe, I Lastres-Becker Cellular and molecular neurobiology 39, 331-340, 2019 | 20 | 2019 |
| Tuning melatonin receptor subtype selectivity in oxadiazolone-based analogues: Discovery of QR2 ligands and NRF2 activators with neurogenic properties C Herrera-Arozamena, M Estrada-Valencia, C Pérez, L Lagartera, ... European Journal of Medicinal Chemistry 190, 112090, 2020 | 19 | 2020 |
| α-Synuclein induces the GSK-3-mediated phosphorylation and degradation of NURR1 and loss of dopaminergic hallmarks ÁJ García-Yagüe, I Lastres-Becker, L Stefanis, DK Vassilatis, A Cuadrado Molecular Neurobiology 58, 6697-6711, 2021 | 8 | 2021 |
| Mechanisms of NURR1 regulation: Consequences for Its biological activity and involvement in pathology ÁJ García-Yagüe, A Cuadrado International Journal of Molecular Sciences 24 (15), 12280, 2023 | 4 | 2023 |
| Impaired signaling of NF-κB and NRF2 in CX3CR1-deficient microglia: Implications in tauopathies S Castro-Sánchez, ÁJ García-Yagüe, S Kügler, I Lastres-Becker BioRxiv, 346304, 2018 | 1 | 2018 |
| Identification of the NRF2/β-TrCP axis to protect against non-alcoholic steatohepatitis. R Fernández-Ginés, R Míguez, JA Encinar, M Escoll, ... Free Radical Biology and Medicine 218, 15, 2024 | | 2024 |
| Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH R Fernández-Ginés, JA Encinar, M Escoll, D Carnicero-Senabre, ... Redox Biology 69, 103027, 2024 | | 2024 |
| Transcription factor NRF2 regulates the permeability of the blood brain barrier at the level of ANGPT1/2-TIE2 signaling E Cazalla, AJ García-Yagüe, M Pajares, J Jiménez-Villegas, A Cuadrado Free Radical Biology and Medicine 201, 16-17, 2023 | | 2023 |
| Regulation of the extracellular matrix glycoprotein Reelin by the transcription factor NRF2: A protective mechanism for the brain under oxidative stress ÁJ García-Yagüe, A Cuadrado Free Radical Biology and Medicine 165, 48, 2021 | | 2021 |
| Surface plasmon resonance for the discovery of new non-electrophilic inhibitors of KEAP1-NRF2 protein-protein interaction M Estrada-Valencia, C Herrera-Arozamena, L Lagartera, A Cuadrado, ... | | 2019 |
| Impaired signaling of Transcription factors NF-ƘB and NRF2 in CX3CR1-deficient microglia leads to altered neuroinflammation and phagocytosis: implications in tauopathies S Castro-Sánchez, ÁJ García-Yagüe, M Galán-Ganga, T López-Royo, ... | | 2018 |
| Regulación del procesamiento de la Reelina por Nrf2 ÁJ García-Yagüe, A Cuadrado | | 2017 |
| Role of the transcription factor NRF2 in the regulation of macroautopahgy and its impact in a new mouse model of AD M Pajares, N Jiménez-Moreno, ÁJ García-Yagüe, M Escoll, AI Rojo, ... | | 2016 |
