Chemokines and cytokines in neuroinflammation leading to neuropathic pain N Kiguchi, Y Kobayashi, S Kishioka Current opinion in pharmacology 12 (1), 55-61, 2012 | 286 | 2012 |
Macrophage inflammatory protein-1α mediates the development of neuropathic pain following peripheral nerve injury through interleukin-1β up-regulation N Kiguchi, T Maeda, Y Kobayashi, Y Fukazawa, S Kishioka Pain 149 (2), 305-315, 2010 | 193 | 2010 |
Leptin enhances CC-chemokine ligand expression in cultured murine macrophage N Kiguchi, T Maeda, Y Kobayashi, Y Fukazawa, S Kishioka Biochemical and biophysical research communications 384 (3), 311-315, 2009 | 167 | 2009 |
A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates H Ding, N Kiguchi, D Yasuda, PR Daga, WE Polgar, JJ Lu, PW Czoty, ... Science translational medicine 10 (456), eaar3483, 2018 | 127 | 2018 |
Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation T Maeda, N Kiguchi, Y Kobayashi, T Ikuta, M Ozaki, S Kishioka Proceedings of the National Academy of Sciences 106 (31), 13076-13081, 2009 | 125 | 2009 |
Epigenetic augmentation of the macrophage inflammatory protein 2/CXC chemokine receptor type 2 axis through histone H3 acetylation in injured peripheral nerves elicits … N Kiguchi, Y Kobayashi, T Maeda, Y Fukazawa, K Tohya, M Kimura, ... Journal of Pharmacology and Experimental Therapeutics 340 (3), 577-587, 2012 | 119 | 2012 |
A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates H Ding, PW Czoty, N Kiguchi, G Cami-Kobeci, DD Sukhtankar, MA Nader, ... Proceedings of the National Academy of Sciences 113 (37), E5511-E5518, 2016 | 105 | 2016 |
Peripheral interleukin-4 ameliorates inflammatory macrophage-dependent neuropathic pain N Kiguchi, Y Kobayashi, F Saika, H Sakaguchi, T Maeda, S Kishioka Pain 156 (4), 684-693, 2015 | 102 | 2015 |
CC‐chemokine ligand 4/macrophage inflammatory protein‐1β participates in the induction of neuropathic pain after peripheral nerve injury F Saika, N Kiguchi, Y Kobayashi, Y Fukazawa, S Kishioka European journal of pain 16 (9), 1271-1280, 2012 | 101 | 2012 |
The critical role of invading peripheral macrophage-derived interleukin-6 in vincristine-induced mechanical allodynia in mice N Kiguchi, T Maeda, Y Kobayashi, T Kondo, M Ozaki, S Kishioka European journal of pharmacology 592 (1-3), 87-92, 2008 | 100 | 2008 |
Pharmacological regulation of neuropathic pain driven by inflammatory macrophages N Kiguchi, D Kobayashi, F Saika, S Matsuzaki, S Kishioka International journal of molecular sciences 18 (11), 2296, 2017 | 94 | 2017 |
Macrophage-T cell interactions mediate neuropathic pain through the glucocorticoid-induced tumor necrosis factor ligand system Y Kobayashi, N Kiguchi, Y Fukazawa, F Saika, T Maeda, S Kishioka Journal of Biological Chemistry 290 (20), 12603-12613, 2015 | 93 | 2015 |
Pioglitazone attenuates tactile allodynia and thermal hyperalgesia in mice subjected to peripheral nerve injury T Maeda, N Kiguchi, Y Kobayashi, M Ozaki, S Kishioka Journal of pharmacological sciences 108 (3), 341-347, 2008 | 93 | 2008 |
Epigenetic upregulation of CCL2 and CCL3 via histone modifications in infiltrating macrophages after peripheral nerve injury N Kiguchi, Y Kobayashi, F Saika, S Kishioka Cytokine 64 (3), 666-672, 2013 | 91 | 2013 |
Up-regulation of tumor necrosis factor-alpha in spinal cord contributes to vincristine-induced mechanical allodynia in mice N Kiguchi, T Maeda, Y Kobayashi, S Kishioka Neuroscience letters 445 (2), 140-143, 2008 | 84 | 2008 |
Negative relationship between morphine analgesia and P-glycoprotein expression levels in the brain W Hamabe, T Maeda, N Kiguchi, C Yamamoto, S Tokuyama, S Kishioka Journal of pharmacological sciences 105 (4), 353-360, 2007 | 78 | 2007 |
LPA-mediated demyelination in ex vivo culture of dorsal root R Fujita, N Kiguchi, H Ueda Neurochemistry international 50 (2), 351-355, 2007 | 74 | 2007 |
Nicotine effects and the endogenous opioid system S Kishioka, N Kiguchi, Y Kobayashi, F Saika Journal of pharmacological sciences 125 (2), 117-124, 2014 | 70 | 2014 |
Involvement of inflammatory mediators in neuropathic pain caused by vincristine N Kiguchi, T Maeda, Y Kobayashi, F Saika, S Kishioka International review of neurobiology 85, 179-190, 2009 | 66 | 2009 |
CC-chemokine MIP-1α in the spinal cord contributes to nerve injury-induced neuropathic pain N Kiguchi, Y Kobayashi, T Maeda, F Saika, S Kishioka Neuroscience letters 484 (1), 17-21, 2010 | 63 | 2010 |