| Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases CL Hartley, S Edwards, L Mullan, PA Bell, M Fresquet, RP Boot-Handford, ... Human molecular genetics 22 (25), 5262-5275, 2013 | 87 | 2013 |
| An unfolded protein response is the initial cellular response to the expression of mutant matrilin-3 in a mouse model of multiple epiphyseal dysplasia S Nundlall, MH Rajpar, PA Bell, C Clowes, LAH Zeeff, B Gardner, ... Cell Stress and Chaperones 15, 835-849, 2010 | 79 | 2010 |
| Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome I Pablos, Y Machado, HCR de Jesus, Y Mohamud, R Kappelhoff, ... Cell reports 37 (4), 2021 | 75 | 2021 |
| Genotype to phenotype correlations in cartilage oligomeric matrix protein associated chondrodysplasias MD Briggs, J Brock, SC Ramsden, PA Bell European Journal of Human Genetics 22 (11), 1278-1282, 2014 | 54 | 2014 |
| New therapeutic targets in rare genetic skeletal diseases MD Briggs, PA Bell, MJ Wright, KA Pirog Expert opinion on orphan drugs 3 (10), 1137-1154, 2015 | 38 | 2015 |
| The utility of mouse models to provide information regarding the pathomolecular mechanisms in human genetic skeletal diseases: The emerging role of endoplasmic reticulum stress MD Briggs, PA Bell, KA Pirog International journal of molecular medicine 35 (6), 1483-1492, 2015 | 36 | 2015 |
| Abnormal chondrocyte apoptosis in the cartilage growth plate is influenced by genetic background and deletion of CHOP in a targeted mouse model of pseudoachondroplasia KA Piróg, A Irman, S Young, P Halai, PA Bell, RP Boot-Handford, ... PloS one 9 (2), e85145, 2014 | 35 | 2014 |
| Mesencephalic astrocyte-derived neurotropic factor is an important factor in chondrocyte ER homeostasis PA Bell, EP Dennis, CL Hartley, RM Jackson, A Porter, RP Boot-Handford, ... Cell Stress and Chaperones 24, 159-173, 2019 | 25 | 2019 |
| A novel transgenic mouse model of growth plate dysplasia reveals that decreased chondrocyte proliferation due to chronic ER stress is a key factor in reduced bone growth B Gualeni, MH Rajpar, A Kellogg, PA Bell, P Arvan, RP Boot-Handford, ... Disease models & mechanisms 6 (6), 1414-1425, 2013 | 25 | 2013 |
| Proteomic and N-terminomic TAILS analyses of human alveolar bone proteins: improved protein extraction methodology and LysargiNase digestion strategies increase proteome … PA Bell, N Solis, JN Kizhakkedathu, I Matthew, CM Overall Journal of proteome research 18 (12), 4167-4179, 2019 | 24 | 2019 |
| Mechanistic understanding of the combined immunodeficiency in complete human CARD11 deficiency HY Lu, M Sharma, AA Sharma, A Lacson, A Szpurko, J Luider, ... Journal of Allergy and Clinical Immunology 148 (6), 1559-1574. e13, 2021 | 23 | 2021 |
| Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase PG Jobin, N Solis, Y Machado, PA Bell, NH Kwon, S Kim, CM Overall, ... Journal of Biological Chemistry 294 (35), 12866-12879, 2019 | 21 | 2019 |
| Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage PG Jobin, N Solis, Y Machado, PA Bell, SK Rai, NH Kwon, S Kim, ... Journal of Biological Chemistry 295 (8), 2186-2202, 2020 | 19 | 2020 |
| Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures PA Bell, R Wagener, F Zaucke, M Koch, J Selley, S Warwood, D Knight, ... Biology open 2 (8), 802-811, 2013 | 18 | 2013 |
| Integrating knowledge of protein sequence with protein function for the prediction and validation of new MALT1 substrates PA Bell, S Scheuermann, F Renner, CL Pan, HY Lu, SE Turvey, ... Computational and Structural Biotechnology Journal 20, 4717-4732, 2022 | 11 | 2022 |
| Loss of matrilin 1 does not exacerbate the skeletal phenotype in a mouse model of multiple epiphyseal dysplasia caused by a Matn3 V194D mutation PA Bell, KA Piróg, M Fresquet, DJ Thornton, RP Boot‐Handford, ... Arthritis & Rheumatism 64 (5), 1529-1539, 2012 | 9 | 2012 |
| No Substrate Left behind—Mining of Shotgun Proteomics Datasets Rescues Evidence of Proteolysis by SARS-CoV-2 3CLpro Main Protease PA Bell, CM Overall International Journal of Molecular Sciences 24 (10), 8723, 2023 | 3 | 2023 |
| Pseudoachondroplasia and multiple epiphyseal dysplasia: Molecular genetics, disease mechanisms and therapeutic targets MD Briggs, P Bell, KA Piróg Cartilage: Volume 2: Pathophysiology, 135-153, 2017 | 2 | 2017 |
| Animal models and systems biology approaches for the functional validation of genetic determinants of skeletal diseases PA Bell, MD Briggs BMC Musculoskeletal Disorders 16 (1), 1-1, 2015 | | 2015 |
| Shared therapeutic targets in genetic skeletal diseases MD Briggs, KA Pirog, PA Bell Bone Abstracts 4, 2015 | | 2015 |
