A pan-cancer proteogenomic atlas of PI3K/AKT/mTOR pathway alterations Y Zhang, PKS Ng, M Kucherlapati, F Chen, Y Liu, YH Tsang, ... Cancer cell 31 (6), 820-832. e3, 2017 | 526 | 2017 |
The genomic landscape and clinical relevance of A-to-I RNA editing in human cancers L Han, L Diao, S Yu, X Xu, J Li, R Zhang, Y Yang, HMJ Werner, ... Cancer cell 28 (4), 515-528, 2015 | 483 | 2015 |
Comprehensive molecular characterization of the hippo signaling pathway in cancer Y Wang, X Xu, D Maglic, MT Dill, K Mojumdar, PKS Ng, KJ Jeong, ... Cell reports 25 (5), 1304-1317. e5, 2018 | 367 | 2018 |
Systematic functional annotation of somatic mutations in cancer PKS Ng, J Li, KJ Jeong, S Shao, H Chen, YH Tsang, S Sengupta, Z Wang, ... Cancer cell 33 (3), 450-462. e10, 2018 | 252 | 2018 |
A-to-I RNA editing contributes to proteomic diversity in cancer X Peng, X Xu, Y Wang, DH Hawke, S Yu, L Han, Z Zhou, K Mojumdar, ... Cancer cell 33 (5), 817-828. e7, 2018 | 181 | 2018 |
Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers Y Wang, X Xu, S Yu, KJ Kang, Z Zhou, L Han, YH Tsang, J Li, H Chen, ... Genome Research, gr. 219741.116, 2017 | 164 | 2017 |
Identification of variant-specific functions of PIK3CA by rapid phenotyping of rare mutations T Dogruluk, YH Tsang, M Espitia, F Chen, T Chen, Z Chong, V Appadurai, ... Cancer research 75 (24), 5341-5354, 2015 | 156 | 2015 |
RNA editing derived epitopes function as cancer antigens to elicit immune responses M Zhang, J Fritsche, J Roszik, LJ Williams, X Peng, Y Chiu, CC Tsou, ... Nature communications 9 (1), 3919, 2018 | 130 | 2018 |
Functional annotation of rare gene aberration drivers of pancreatic cancer YH Tsang, T Dogruluk, PM Tedeschi, J Wardwell-Ozgo, H Lu, M Espitia, ... Nature communications 7 (1), 10500, 2016 | 64 | 2016 |
Cyclin A2-Cyclin-Dependent Kinase 2 Cooperates with the PLK1-SCFβ-TrCP1-EMI1-Anaphase-Promoting Complex/Cyclosome Axis To Promote Genome … HT Ma, YH Tsang, M Marxer, RYC Poon Molecular and cellular biology 29 (24), 6500-6514, 2009 | 63 | 2009 |
A-to-I–edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis X Xu, Y Wang, K Mojumdar, Z Zhou, KJ Jeong, LS Mangala, S Yu, ... The Journal of clinical investigation 129 (12), 5343-5356, 2019 | 56 | 2019 |
Comprehensive assessment of computational algorithms in predicting cancer driver mutations H Chen, J Li, Y Wang, PKS Ng, YH Tsang, KR Shaw, GB Mills, H Liang Genome biology 21, 1-17, 2020 | 50 | 2020 |
Engineering and functional characterization of fusion genes identifies novel oncogenic drivers of cancer H Lu, N Villafane, T Dogruluk, CL Grzeskowiak, K Kong, YH Tsang, ... Cancer research 77 (13), 3502-3512, 2017 | 42 | 2017 |
An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells HT Ma, KF On, YH Tsang, RYC Poon Nucleic acids research 35 (4), e22, 2007 | 42 | 2007 |
In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer CL Grzeskowiak, ST Kundu, X Mo, AA Ivanov, O Zagorodna, H Lu, ... Nature communications 9 (1), 2732, 2018 | 39 | 2018 |
Salt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death H Chen, S Huang, X Han, J Zhang, C Shan, YH Tsang, HT Ma, RYC Poon Cell death & disease 5 (4), e1177-e1177, 2014 | 29 | 2014 |
Novel functions of the phosphatase SHP2 in the DNA replication and damage checkpoints YH Tsang, X Han, WY Man, N Lee, RYC Poon PLoS One 7 (11), e49943, 2012 | 27 | 2012 |
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer X Mo, Q Niu, AA Ivanov, YH Tsang, C Tang, C Shu, Q Li, K Qian, ... Cell 185 (11), 1974-1985. e12, 2022 | 20 | 2022 |
Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression YH Tsang, Y Wang, K Kong, C Grzeskowiak, O Zagorodna, T Dogruluk, ... Elife 9, e48963, 2020 | 20 | 2020 |
Clinical and functional characterization of atypical KRAS/NRAS mutations in metastatic colorectal cancer JM Loree, Y Wang, MA Syed, AV Sorokin, O Coker, J Xiu, BA Weinberg, ... Clinical Cancer Research 27 (16), 4587-4598, 2021 | 18 | 2021 |