Target identification using drug affinity responsive target stability (DARTS) B Lomenick, R Hao, N Jonai, RM Chin, M Aghajan, S Warburton, J Wang, ... Proceedings of the National Academy of Sciences 106 (51), 21984-21989, 2009 | 845 | 2009 |
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR RM Chin, X Fu, MY Pai, L Vergnes, H Hwang, G Deng, S Diep, ... Nature 510 (7505), 397-401, 2014 | 570 | 2014 |
Identification of direct protein targets of small molecules B Lomenick, RW Olsen, J Huang ACS chemical biology 6 (1), 34-46, 2011 | 346 | 2011 |
Drug affinity responsive target stability (DARTS) for small-molecule target identification MY Pai, B Lomenick, H Hwang, R Schiestl, W McBride, JA Loo, J Huang Chemical Biology: Methods and Protocols, 287-298, 2015 | 243 | 2015 |
Target identification using drug affinity responsive target stability (DARTS) B Lomenick, G Jung, JA Wohlschlegel, J Huang Current protocols in chemical biology 3 (4), 163-180, 2011 | 196 | 2011 |
Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase M Aghajan, N Jonai, K Flick, F Fu, M Luo, X Cai, I Ouni, N Pierce, X Tang, ... Nature biotechnology 28 (7), 738-742, 2010 | 145 | 2010 |
Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells GI Aldana-Masangkay, A Rodriguez-Gonzalez, T Lin, AK Ikeda, YT Hsieh, ... Leukemia & lymphoma 52 (8), 1544-1555, 2011 | 67 | 2011 |
LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding CS Shin, S Meng, SD Garbis, A Moradian, RW Taylor, MJ Sweredoski, ... Nature Communications 12 (1), 265, 2021 | 63 | 2021 |
MTCH2 is a mitochondrial outer membrane protein insertase A Guna, TA Stevens, AJ Inglis, JM Replogle, TK Esantsi, G Muthukumar, ... Science 378 (6617), 317-322, 2022 | 33 | 2022 |
Identification and characterization of β-sitosterol target proteins B Lomenick, H Shi, J Huang, C Chen Bioorganic & medicinal chemistry letters 25 (21), 4976-4979, 2015 | 29 | 2015 |
A proteome-wide map of 20 (S)-hydroxycholesterol interactors in cell membranes YS Cheng, T Zhang, X Ma, S Pratuangtham, GC Zhang, AA Ondrus, ... Nature chemical biology 17 (12), 1271-1280, 2021 | 28 | 2021 |
Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α–dependent pathways I Morianos, AI Trochoutsou, G Papadopoulou, M Semitekolou, A Banos, ... Proceedings of the National Academy of Sciences 117 (22), 12269-12280, 2020 | 25 | 2020 |
The Chemistry and Biology of Nakiterpiosin–C-nor-D-Homosteroids S Gao, Q Wang, G Wang, B Lomenick, J Liu, CW Fan, LW Deng, J Huang, ... Synlett 23 (16), 2298-2310, 2012 | 13 | 2012 |
Adaptive exchange sustains cullin–RING ubiquitin ligase networks and proper licensing of DNA replication Y Zhang, M Jost, RA Pak, D Lu, J Li, B Lomenick, SD Garbis, CM Li, ... Proceedings of the National Academy of Sciences 119 (36), e2205608119, 2022 | 7 | 2022 |
Enzyme Replacement Therapy for Mucopolysaccharidosis IIID using Recombinant Human α-N-Acetylglucosamine-6-Sulfatase in Neonatal Mice F Wang, DR Moen, C Sauni, S Kan, S Li, SQ Le, B Lomenick, X Zhang, ... Molecular Pharmaceutics 18 (1), 214-227, 2020 | 7 | 2020 |
Sperm can act as vectors for HIV‐1 transmission into vaginal and cervical epithelial cells CD Young, S Tatieng, K Kongmanas, D Fongmoon, B Lomenick, AJ Yoon, ... American Journal of Reproductive Immunology 82 (1), e13129, 2019 | 7 | 2019 |
Surface cysteines could protect the SARS-CoV-2 main protease from oxidative damage R Ravanfar, Y Sheng, M Shahgholi, B Lomenick, J Jones, TF Chou, ... Journal of Inorganic Biochemistry 234, 111886, 2022 | 6 | 2022 |
Mechanisms of chlorate toxicity and resistance in Pseudomonas aeruginosa MA Spero, J Jones, B Lomenick, TF Chou, DK Newman Molecular Microbiology 118 (4), 321-335, 2022 | 5 | 2022 |
Amino Acid Analog Induces Stress Response in Marine Synechococcus DE Michels, B Lomenick, TF Chou, MJ Sweredoski, A Pasulka Applied and environmental microbiology 87 (15), e00200-21, 2021 | 5 | 2021 |
Ketobutyrate compounds and compositions for treating age-related symptoms and diseases J Huang, RM Chin, X Fu, H Hwang, K Reue, L Vergnes, M Jiang, ... US Patent 10,729,668, 2020 | 5 | 2020 |