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Gareth J Williams
Gareth J Williams
Assistant Professor, Biochemistry & Molecular Biology, University of Calgary
在 ucalgary.ca 的电子邮件经过验证
标题
引用次数
引用次数
年份
Mre11–Rad50–Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks
GJ Williams, SP Lees-Miller, JA Tainer
DNA repair 9 (12), 1299-1306, 2010
2922010
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2
E Dray, J Etchin, C Wiese, D Saro, GJ Williams, M Hammel, X Yu, ...
Nature structural & molecular biology 17 (10), 1255-1259, 2010
1922010
ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair
GJ Williams, RS Williams, JS Williams, G Moncalian, AS Arvai, O Limbo, ...
Nature structural & molecular biology 18 (4), 423-431, 2011
1802011
A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51
N Ameziane, P May, A Haitjema, HJ Van De Vrugt, ...
Nature communications 6 (1), 8829, 2015
1782015
ATP‐driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling
RA Deshpande, GJ Williams, O Limbo, RS Williams, J Kuhnlein, JH Lee, ...
The EMBO journal 33 (5), 482-500, 2014
1612014
Promotion of homologous recombination and genomic stability by RAD51AP1 via RAD51 recombinase enhancement
C Wiese, E Dray, T Groesser, J San Filippo, I Shi, DW Collins, MS Tsai, ...
Molecular cell 28 (3), 482-490, 2007
1562007
Rare key functional domain missense substitutions in MRE11A, RAD50, and NBNcontribute to breast cancer susceptibility: results from a Breast Cancer Family …
F Damiola, M Pertesi, J Oliver, F Le Calvez-Kelm, C Voegele, EL Young, ...
Breast Cancer Research 16, 1-16, 2014
1422014
Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair
J Lafrance-Vanasse, GJ Williams, JA Tainer
Progress in biophysics and molecular biology 117 (2-3), 182-193, 2015
1392015
Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time
GJ Williams, M Hammel, SK Radhakrishnan, D Ramsden, SP Lees-Miller, ...
DNA repair 17, 110-120, 2014
1362014
Insights into FlaI functions in archaeal motor assembly and motility from structures, conformations, and genetics
S Reindl, A Ghosh, GJ Williams, K Lassak, T Neiner, AL Henche, ...
Molecular cell 49 (6), 1069-1082, 2013
1072013
ATM-deficient cancers provide new opportunities for precision oncology
NR Jette, M Kumar, S Radhamani, G Arthur, S Goutam, S Yip, M Kolinsky, ...
Cancers 12 (3), 687, 2020
992020
Structure of the heterotrimeric PCNA from Sulfolobus solfataricus
GJ Williams, K Johnson, J Rudolf, SA McMahon, L Carter, M Oke, H Liu, ...
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006
932006
Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis
GJ Williams, SD Breazeale, CRH Raetz, JH Naismith
Journal of Biological Chemistry 280 (24), 23000-23008, 2005
782005
DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals
GL Hura, CL Tsai, SA Claridge, ML Mendillo, JM Smith, GJ Williams, ...
Proceedings of the National Academy of Sciences 110 (43), 17308-17313, 2013
662013
Mechanistic insights into the role of Hop2–Mnd1 in meiotic homologous DNA pairing
W Zhao, D Saro, M Hammel, YH Kwon, Y Xu, RP Rambo, GJ Williams, ...
Nucleic acids research 42 (2), 906-917, 2013
622013
Long noncoding RNA NIHCOLE promotes ligation efficiency of DNA double-strand breaks in hepatocellular carcinoma
JP Unfried, M Marín-Baquero, Á Rivera-Calzada, N Razquin, ...
Cancer research 81 (19), 4910-4925, 2021
382021
Functional attributes of the Saccharomyces cerevisiae meiotic recombinase Dmc1
V Busygina, WA Gaines, Y Xu, Y Kwon, GJ Williams, SW Lin, HY Chang, ...
DNA repair 12 (9), 707-712, 2013
272013
ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining
H Lu, Q Zhang, DJ Laverty, AC Puncheon, MM Augustine, GJ Williams, ...
Nucleic acids research 51 (13), 6770-6783, 2023
112023
RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles
MA Longo, S Roy, Y Chen, KH Tomaszowski, AS Arvai, JT Pepper, ...
Nature communications 14 (1), 4445, 2023
92023
Cryo-EM structure of DDM1-HELLS chimera bound to nucleosome reveals a mechanism of chromatin remodeling and disease regulation
W Nartey, AA Goodarzi, GJ Williams
bioRxiv, 2023.08. 09.551721, 2023
32023
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