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| Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation A Laurence, CM Tato, TS Davidson, Y Kanno, Z Chen, Z Yao, RB Blank, ... Immunity 26 (3), 371-381, 2007 | 1924 | 2007 |
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| Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells JJ O’Shea, WE Paul Science 327 (5969), 1098-1102, 2010 | 1712 | 2010 |
| Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes MF McDermott, I Aksentijevich, J Galon, EM McDermott, BW Ogunkolade, ... Cell 97 (1), 133-144, 1999 | 1651 | 1999 |
| Cytokine signaling in 2002: new surprises in the Jak/Stat pathway JJ O'Shea, M Gadina, RD Schreiber Cell 109 (2), S121-S131, 2002 | 1490 | 2002 |
| The JAK-STAT pathway: impact on human disease and therapeutic intervention JJ O'Shea, DM Schwartz, AV Villarino, M Gadina, IB McInnes, A Laurence Annual review of medicine 66 (1), 311-328, 2015 | 1460 | 2015 |
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| Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells G Wei, L Wei, J Zhu, C Zang, J Hu-Li, Z Yao, K Cui, Y Kanno, TY Roh, ... Immunity 30 (1), 155-167, 2009 | 1302 | 2009 |
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| JAK inhibition as a therapeutic strategy for immune and inflammatory diseases DM Schwartz, Y Kanno, A Villarino, M Ward, M Gadina, JJ O'Shea Nature reviews Drug discovery 16 (12), 843-862, 2017 | 1221 | 2017 |
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| JAK and STAT signaling molecules in immunoregulation and immune-mediated disease JJ O'Shea, R Plenge Immunity 36 (4), 542-550, 2012 | 1137 | 2012 |
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| Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10 JS Stumhofer, JS Silver, A Laurence, PM Porrett, TH Harris, LA Turka, ... Nature immunology 8 (12), 1363-1371, 2007 | 992 | 2007 |
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| Cytokine signaling modules in inflammatory responses JJ O'Shea, PJ Murray Immunity 28 (4), 477-487, 2008 | 931 | 2008 |
| JAKs and STATs in immunity, immunodeficiency, and cancer JJ O'Shea, SM Holland, LM Staudt New England Journal of Medicine 368 (2), 161-170, 2013 | 904 | 2013 |
