Probing the substrate specificities of matriptase, matriptase‐2, hepsin and DESC1 with internally quenched fluorescent peptides F Béliveau, A Désilets, R Leduc The FEBS journal 276 (8), 2213-2226, 2009 | 124 | 2009 |
Preventing pluripotent cell teratoma in regenerative medicine applied to hematology disorders A Bedel, F Beliveau, I Lamrissi-Garcia, B Rousseau, I Moranvillier, ... Stem cells translational medicine 6 (2), 382-393, 2017 | 71 | 2017 |
Cleavage specificity analysis of six type II transmembrane serine proteases (TTSPs) using PICS with proteome-derived peptide libraries O Barre, A Dufour, U Eckhard, R Kappelhoff, F Beliveau, R Leduc, ... PloS one 9 (9), e105984, 2014 | 69 | 2014 |
Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis X Tang, SS Mahajan, LT Nguyen, F Béliveau, R Leduc, JA Simon, ... Oncotarget 5 (5), 1352, 2014 | 58 | 2014 |
Mutation G827R in matriptase causing autosomal recessive ichthyosis with hypotrichosis yields an inactive protease A Desilets, F Béliveau, G Vandal, FO McDuff, P Lavigne, R Leduc Journal of Biological Chemistry 283 (16), 10535-10542, 2008 | 57 | 2008 |
Discovery and development of TMPRSS6 inhibitors modulating hepcidin levels in human hepatocytes F Béliveau, A Tarkar, SP Dion, A Désilets, MG Ghinet, PL Boudreault, ... Cell Chemical Biology 26 (11), 1559-1572. e9, 2019 | 37 | 2019 |
Variable behavior of iPSCs derived from CML patients for response to TKI and hematopoietic differentiation A Bedel, JM Pasquet, E Lippert, M Taillepierre, V Lagarde, S Dabernat, ... PloS one 8 (8), e71596, 2013 | 37 | 2013 |
Modulating the selectivity of matriptase-2 inhibitors with unnatural amino acids C St-Georges, A Désilets, F Béliveau, M Ghinet, SP Dion, É Colombo, ... European Journal of Medicinal Chemistry 129, 110-123, 2017 | 28 | 2017 |
Essential role of endocytosis of the type II transmembrane serine protease TMPRSS6 in regulating its functionality F Béliveau, C Brulé, A Désilets, B Zimmerman, SA Laporte, CL Lavoie, ... Journal of Biological Chemistry 286 (33), 29035-29043, 2011 | 28 | 2011 |
The type II transmembrane serine protease matriptase cleaves the amyloid precursor protein and reduces its processing to β-amyloid peptide E Lanchec, A Désilets, F Béliveau, A Flamier, S Mahmoud, G Bernier, ... Journal of Biological Chemistry 292 (50), 20669-20682, 2017 | 24 | 2017 |
Functional diversity of TMPRSS6 isoforms and variants expressed in hepatocellular carcinoma cell lines SP Dion, F Béliveau, LP Morency, A Désilets, R Najmanovich, R Leduc Scientific Reports 8 (1), 12562, 2018 | 19 | 2018 |
Effect of tyrosine kinase inhibitors on stemness in normal and chronic myeloid leukemia cells L Charaf, FX Mahon, I Lamrissi-Garcia, I Moranvillier, F Beliveau, ... Leukemia 31 (1), 65-74, 2017 | 19 | 2017 |
Transcriptome analysis reveals TMPRSS6 isoforms with distinct functionalities SP Dion, F Béliveau, A Désilets, MG Ghinet, R Leduc Journal of Cellular and Molecular Medicine 22 (4), 2498-2509, 2018 | 16 | 2018 |
DELE1 haploinsufficiency causes resistance to mitochondrial stress-induced apoptosis in monosomy 5/del(5q) AML JF Spinella, J Chagraoui, C Moison, VP Lavallée, I Boivin, D Gracias, ... Leukemia 38 (3), 530-537, 2024 | 6 | 2024 |
GPRC5C drives branched-chain amino acid metabolism in leukemogenesis YW Zhang, T Velasco-Hernandez, J Mess, ME Lalioti, MC Romero-Mulero, ... Blood Advances 7 (24), 7525-7538, 2023 | 6 | 2023 |
Immunotherapeutic targeting of surfaceome heterogeneity in AML ME Bordeleau, É Audemard, A Métois, L Theret, V Lisi, A Farah, ... Cell Reports 43 (6), 2024 | 4 | 2024 |
Discovery and development of TMPRSS6 inhibitors modulating hepcidin levels in human hepatocytes. Cell Chem Biol. 2019; 26 (11): 1559–72. e9 F Béliveau, A Tarkar, SP Dion, A Désilets, MG Ghinet, PL Boudreault | 3 | |
Spécificité enzymatique et régulation fonctionnelle de la matriptase-2, une protéase à sérine transmembranaire de type II essentielle à l'homéostasie du fer. F Béliveau Library and Archives Canada= Bibliothèque et Archives Canada, Ottawa, 2013 | 2 | 2013 |
Integrated drug resistance and leukemic stemness gene-expression scores predict outcomes in large cohort of over 3500 AML patients from 10 trials A H. Elsayed, X Cao, RJ Marrero, NHK Nguyen, H Wu, Y Ni, RC Ribeiro, ... NPJ Precision Oncology 8 (1), 168, 2024 | 1 | 2024 |
Matriptase processing of APLP1 ectodomain alters its homodimerization E Lanchec, A Désilets, F Béliveau, C Fontaine-Carbonneau, A Laniel, ... Scientific Reports 10 (1), 10091, 2020 | 1 | 2020 |