De novo design of a transmembrane Zn2+-transporting four-helix bundle NH Joh, T Wang, MP Bhate, R Acharya, Y Wu, M Grabe, M Hong, ... Science 346 (6216), 1520-1524, 2014 | 331 | 2014 |
Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins NHJ Joh, A Min, S Faham, JP Whitelegge, D Yang, VL Woods, JU Bowie Nature 453 (7199), 1266, 2008 | 283 | 2008 |
Similar energetic contributions of packing in the core of membrane and water-soluble proteins NH Joh, A Oberai, D Yang, JP Whitelegge, JU Bowie Journal of the American Chemical Society 131 (31), 10846-10847, 2009 | 89 | 2009 |
Methods for measuring the thermodynamic stability of membrane proteins H Hong, NH Joh, JU Bowie, LK Tamm Methods in enzymology 455, 213-236, 2009 | 86 | 2009 |
Structural imperatives impose diverse evolutionary constraints on helical membrane proteins A Oberai, NH Joh, FK Pettit, JU Bowie Proceedings of the National Academy of Sciences 106 (42), 17747-17750, 2009 | 74 | 2009 |
Probing membrane protein unfolding with pulse proteolysis JP Schlebach, MS Kim, NH Joh, JU Bowie, C Park Journal of molecular biology 406 (4), 545-551, 2011 | 45 | 2011 |
Characterization of subvisible particles in biotherapeutic pre-filled syringes: the role of polysorbate and protein on the formation of silicone oil and protein subvisible … N Jiao, GV Barnett, TR Christian, LO Narhi, NH Joh, MK Joubert, S Cao Journal of pharmaceutical sciences, 2019 | 36 | 2019 |
Design of self-assembling transmembrane helical bundles to elucidate principles required for membrane protein folding and ion transport NH Joh, G Grigoryan, Y Wu, WF DeGrado Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017 | 27 | 2017 |
Silicone oil particles in prefilled syringes with human monoclonal antibody representative of real-world drug products did not increase immunogenicity in in vivo and in vitro … NH Joh, L Thomas, TR Christian, A Verlinsky, N Jiao, N Allotta, V Jawa, ... Journal of Pharmaceutical Sciences, 2019 | 23 | 2019 |
Impact of Precipitation of Antibody Therapeutics After Subcutaneous Injection on Pharmacokinetics and Immunogenicity F Kinderman, B Yerby, V Jawa, MK Joubert, NH Joh, J Malella, ... Journal of pharmaceutical sciences 108 (6), 1953-1963, 2019 | 21 | 2019 |
Computational design of metallotransporter N Joh, G Grigoryan, Y Wu, R Acharya, T Wang, M Hong, M Grabe, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014 | | 2014 |
testing the Alternate-access Mechanism by De-novo Designing a Transporter: 440 N Joh, G Grigoryan, Y Wu, R Acharya, W Degrado Protein Science 22, 157-158, 2013 | | 2013 |
Method for screening of antiviral agents M Inouye, L Mao, WF DeGrado, NH Joh US Patent 8,476,037, 2013 | | 2013 |
Method for screening of antiviral agents M Inouye, L Mao, WF DeGrado, NH Joh US Patent 8,476,037, 2013 | | 2013 |
Crystal Structure for Transmembrane Domain of Amantadine-Resistant S31N Mutant M2 Proton Channel from Influenza A Virus at 2.1-Angstrom Resolution N Joh, J Thomaston, W DeGrado Protein Science 21, 2012 | | 2012 |
Testing the Structural Mechanism of Transmembrane Translocation using De-Novo Designed Soft-Metal Transporters with Inverted Dual Topology NH Joh, G Grigoryan, Y Hu, WF DeGrado Biophysical Journal 102 (3), 231a, 2012 | | 2012 |
Monitoring membrane protein unfolding by pulse proteolysis: 226 C Park, J Schlebach, MS Kim, N Joh, J Bowie Protein Science 18, 2009 | | 2009 |
Forces that stabilize membrane proteins NH Joh, D Yang, A Min, J Bowie Biophysical Journal 96 (3), 334a, 2009 | | 2009 |