Artemisinin-derived dimers: potent antimalarial and anticancer agents T Fröhlich, A Çapcı Karagöz, C Reiter, SB Tsogoeva Journal of medicinal chemistry 59 (16), 7360-7388, 2016 | 160 | 2016 |
Synthesis and study of cytotoxic activity of 1, 2, 4-trioxane-and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells C Reiter, AÇ Karagöz, T Fröhlich, V Klein, M Zeino, K Viertel, J Held, ... European journal of medicinal chemistry 75, 403-412, 2014 | 93 | 2014 |
Artemisinin–(Iso) quinoline Hybrids by C− H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria A Çapcı, MM Lorion, H Wang, N Simon, M Leidenberger, MC Borges Silva, ... Angewandte Chemie International Edition 58 (37), 13066-13079, 2019 | 88 | 2019 |
Synthesis of substituted 1, 2, 3-triazoles via metal-free click cycloaddition reactions and alternative cyclization methods HB Jalani, AÇ Karagöz, SB Tsogoeva Synthesis 49 (01), 29-41, 2017 | 79 | 2017 |
Combination of 5-fluorouracil and thymoquinone targets stem cell gene signature in colorectal cancer cells B Ndreshkjana, A Çapci, V Klein, P Chanvorachote, JK Muenzner, ... Cell death & disease 10 (6), 379, 2019 | 62 | 2019 |
Synthesis of new betulinic acid/betulin-derived dimers and hybrids with potent antimalarial and antiviral activities AÇ Karagöz, M Leidenberger, F Hahn, F Hampel, O Friedrich, ... Bioorganic & medicinal chemistry 27 (1), 110-115, 2019 | 55 | 2019 |
Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo) egonol, thymoquinone and artemisinin AÇ Karagöz, C Reiter, EJ Seo, L Gruber, F Hahn, M Leidenberger, V Klein, ... Bioorganic & Medicinal Chemistry 26 (12), 3610-3618, 2018 | 54 | 2018 |
New artesunic acid homodimers: Potent reversal agents of multidrug resistance in leukemia cells C Reiter, A Herrmann, A Çapci, T Efferth, SB Tsogoeva Bioorganic & medicinal chemistry 20 (18), 5637-5641, 2012 | 51 | 2012 |
Synthesis, antimicrobial and cytotoxic activities, and structure–activity relationships of gypsogenin derivatives against human cancer cells S Emirdağ-Öztürk, T Karayıldırım, A Çapcı-Karagöz, Ö Alankuş-Çalışkan, ... European Journal of Medicinal Chemistry 82, 565-573, 2014 | 37 | 2014 |
Cytotoxic profiling of artesunic and betulinic acids and their synthetic hybrid compound on neurons and gliomas A Ackermann, AÇ Karagöz, A Ghoochani, M Buchfelder, I Eyüpoglu, ... Oncotarget 8 (37), 61457, 2017 | 27 | 2017 |
(Iso) Quinoline–Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses A Çapcı, MM Lorion, C Mai, F Hahn, J Hodek, C Wangen, J Weber, ... Chemistry–A European Journal 26 (52), 12019-12026, 2020 | 23 | 2020 |
Synthesis and in vitro study of artemisinin/synthetic peroxide‐based hybrid compounds against SARS‐CoV‐2 and cancer L Herrmann, IA Yaremenko, A Çapcı, J Struwe, D Tailor, A Dheeraj, ... ChemMedChem 17 (9), e202200005, 2022 | 20 | 2022 |
Artemisinin‐derived dimers from a chemical perspective A Çapcı, L Herrmann, HM Sampath Kumar, T Fröhlich, SB Tsogoeva Medicinal Research Reviews 41 (6), 2927-2970, 2021 | 20 | 2021 |
Target verification of artesunate-related antiviral drugs: Assessing the role of mitochondrial and regulatory proteins by click chemistry and fluorescence labeling F Hahn, A Niesar, C Wangen, M Wild, B Grau, L Herrmann, A Capci, ... Antiviral Research 180, 104861, 2020 | 15 | 2020 |
Chemical hybridization of sulfasalazine and dihydroartemisinin promotes brain tumor cell death A Ackermann, A Çapcı, M Buchfelder, SB Tsogoeva, N Savaskan Scientific Reports 11 (1), 20766, 2021 | 11 | 2021 |
Studies of Potency and Efficacy of an Optimized Artemisinin-Quinoline Hybrid against Multiple Stages of the Plasmodium Life Cycle HC Quadros, A Çapcı, L Herrmann, S D’Alessandro, D Fontinha, ... Pharmaceuticals 14 (11), 1129, 2021 | 10 | 2021 |
Autofluorescent antimalarials by hybridization of artemisinin and coumarin: in vitro/in vivo studies and live-cell imaging L Herrmann, M Leidenberger, AS de Morais, C Mai, A Çapci, MCB Silva, ... Chemical Science 14 (45), 12941-12952, 2023 | 4 | 2023 |
Artemisinin and quinoline hybrid compounds inhibit replication of SARS-CoV-2 In Vitro L Herrmann, I Yaremenko, A Çapcı, J Struwe, J Hodek, Y Belyakova, ... | 2 | 2021 |
Cover Feature:(Iso) Quinoline–Artemisinin Hybrids Prepared through Click Chemistry: Highly Potent Agents against Viruses (Chem. Eur. J. 52/2020) A Çapcı, MM Lorion, C Mai, F Hahn, J Hodek, C Wangen, J Weber, ... Chemistry–A European Journal 26 (52), 11912-11912, 2020 | 1 | 2020 |
Inside Back Cover: Artemisinin–(Iso) quinoline Hybrids by C− H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. Int. Ed. 37/2019) A Çapcı, MM Lorion, H Wang, N Simon, M Leidenberger, MC Borges Silva, ... Angewandte Chemie International Edition 58 (37), 13161-13161, 2019 | 1 | 2019 |