| The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth J Secombe, L Li, L Carlos, RN Eisenman Genes & development 21 (5), 537-551, 2007 | 315 | 2007 |
| Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock L DiTacchio, HD Le, C Vollmers, M Hatori, M Witcher, J Secombe, ... Science 333 (6051), 1881-1885, 2011 | 279 | 2011 |
| Essential functions of the histone demethylase lid L Li, C Greer, RN Eisenman, J Secombe PLoS genetics 6 (11), e1001221, 2010 | 156 | 2010 |
| Drosophila histone demethylase KDM5 regulates social behavior through immune control and gut microbiota maintenance K Chen, X Luan, Q Liu, J Wang, X Chang, AM Snijders, JH Mao, ... Cell Host & Microbe 25 (4), 537-552. e8, 2019 | 154 | 2019 |
| Myc: a weapon of mass destruction J Secombe, SB Pierce, RN Eisenman Cell 117 (2), 153-156, 2004 | 148 | 2004 |
| decapentaplegic is required for arrest in G1 phase during Drosophila eye development J Horsfield, A Penton, J Secombe, FM Hoffman, H Richardson Development 125 (24), 5069-5078, 1998 | 125 | 1998 |
| Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye NA Grzeschik, N Amin, J Secombe, AM Brumby, HE Richardson Developmental biology 311 (1), 106-123, 2007 | 108 | 2007 |
| The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: the Myc connection J Secombe, RN Eisenman Cell Cycle 6 (11), 1324-1328, 2007 | 108 | 2007 |
| The histone demethylase KDM5 activates gene expression by recognizing chromatin context through its PHD reader motif X Liu, J Secombe Cell reports 13 (10), 2219-2231, 2015 | 85 | 2015 |
| Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling P Navarro-Costa, A McCarthy, P Prudêncio, C Greer, LG Guilgur, ... Nature communications 7 (1), 12331, 2016 | 79 | 2016 |
| The Transcriptional Repressor dMnt Is a Regulator of Growth in Drosophila melanogaster LWM Loo, J Secombe, JT Little, LS Carlos, C Yost, PF Cheng, EM Flynn, ... Molecular and cellular biology 25 (16), 7078-7091, 2005 | 63 | 2005 |
| A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila A Brumby, J Secombe, J Horsfield, M Coombe, N Amin, D Coates, R Saint, ... Genetics 168 (1), 227-251, 2004 | 62 | 2004 |
| Drosophila cyclin E interacts with components of the Brahma complex AM Brumby, CB Zraly, JA Horsfield, J Secombe, R Saint, AK Dingwall, ... The EMBO journal, 2002 | 62 | 2002 |
| Analysis of a Drosophila cyclin E hypomorphic mutation suggests a novel role for cyclin E in cell proliferation control during eye imaginal disc development J Secombe, J Pispa, R Saint, H Richardson Genetics 149 (4), 1867-1882, 1998 | 55 | 1998 |
| A Drosophila model of intellectual disability caused by mutations in the histone demethylase KDM5 S Zamurrad, HAM Hatch, C Drelon, HM Belalcazar, J Secombe Cell reports 22 (9), 2359-2369, 2018 | 53 | 2018 |
| KDM5 interacts with Foxo to modulate cellular levels of oxidative stress X Liu, C Greer, J Secombe PLoS genetics 10 (10), e1004676, 2014 | 53 | 2014 |
| Myc-dependent genome instability and lifespan in Drosophila C Greer, M Lee, M Westerhof, B Milholland, R Spokony, J Vijg, J Secombe PloS one 8 (9), e74641, 2013 | 47 | 2013 |
| The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila C Drelon, HM Belalcazar, J Secombe Genetics 209 (3), 773-787, 2018 | 26 | 2018 |
| Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein J Secombe, SM Parkhurst Journal of Biological Chemistry 279 (17), 17126-17133, 2004 | 26 | 2004 |
| The histone demethylase KDM5 controls developmental timing in Drosophila by promoting prothoracic gland endocycles C Drelon, MF Rogers, HM Belalcazar, J Secombe Development 146 (24), dev182568, 2019 | 23 | 2019 |
Robert N EisenmanDivision of Basic Sciences, Fred Hutchinson Cancer Research Center在 fhcrc.org 的电子邮件经过验证
