| Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations F Muecksch, Y Weisblum, CO Barnes, F Schmidt, D Schaefer-Babajew, ... Immunity 54 (8), 1853-1868. e7, 2021 | 250 | 2021 |
| IL-15 regulates homeostasis and terminal maturation of NKT cells LE Gordy, JS Bezbradica, AI Flyak, CT Spencer, A Dunkle, J Sun, ... The Journal of Immunology 187 (12), 6335-6345, 2011 | 191 | 2011 |
| Cross-reactive and potent neutralizing antibody responses in human survivors of natural ebolavirus infection AI Flyak, X Shen, CD Murin, HL Turner, JA David, ML Fusco, R Lampley, ... Cell 164 (3), 392-405, 2016 | 174 | 2016 |
| Mechanism of human antibody-mediated neutralization of Marburg virus AI Flyak, PA Ilinykh, CD Murin, T Garron, X Shen, ML Fusco, T Hashiguchi, ... Cell 160 (5), 893-903, 2015 | 161 | 2015 |
| Isolation and characterization of broad and ultrapotent human monoclonal antibodies with therapeutic activity against chikungunya virus SA Smith, LA Silva, JM Fox, AI Flyak, N Kose, G Sapparapu, ... Cell host & microbe 18 (1), 86-95, 2015 | 152 | 2015 |
| Structural basis for Marburg virus neutralization by a cross-reactive human antibody T Hashiguchi, ML Fusco, ZA Bornholdt, JE Lee, AI Flyak, R Matsuoka, ... Cell 160 (5), 904-912, 2015 | 140 | 2015 |
| Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance JR Bailey, AI Flyak, VJ Cohen, H Li, LN Wasilewski, AE Snider, S Wang, ... JCI insight 2 (9), 2017 | 128 | 2017 |
| A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses AZ Wec, EK Nyakatura, AS Herbert, KA Howell, FW Holtsberg, RR Bakken, ... Science 354 (6310), 350-354, 2016 | 127 | 2016 |
| Host-primed Ebola virus GP exposes a hydrophobic NPC1 receptor-binding pocket, revealing a target for broadly neutralizing antibodies ZA Bornholdt, E Ndungo, ML Fusco, S Bale, AI Flyak, JE Crowe Jr, ... MBio 7 (1), 10.1128/mbio. 02154-15, 2016 | 111 | 2016 |
| HCV broadly neutralizing antibodies use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design AI Flyak, S Ruiz, MD Colbert, T Luong, JE Crowe, JR Bailey, PJ Bjorkman Cell host & microbe 24 (5), 703-716. e3, 2018 | 110 | 2018 |
| Structures of Ebola virus GP and sGP in complex with therapeutic antibodies J Pallesen, CD Murin, N De Val, CA Cottrell, KM Hastie, HL Turner, ... Nature microbiology 1 (9), 1-9, 2016 | 107 | 2016 |
| Broadly neutralizing antibody mediated clearance of human hepatitis C virus infection VJ Kinchen, MN Zahid, AI Flyak, MG Soliman, GH Learn, S Wang, ... Cell host & microbe 24 (5), 717-730. e5, 2018 | 90 | 2018 |
| Antibody-dependent enhancement of Ebola virus infection by human antibodies isolated from survivors NA Kuzmina, P Younan, P Gilchuk, RI Santos, AI Flyak, PA Ilinykh, ... Cell reports 24 (7), 1802-1815. e5, 2018 | 87 | 2018 |
| Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody CE Mire, JB Geisbert, V Borisevich, KA Fenton, KN Agans, AI Flyak, ... Science translational medicine 9 (384), eaai8711, 2017 | 83 | 2017 |
| Multifunctional pan-ebolavirus antibody recognizes a site of broad vulnerability on the ebolavirus glycoprotein P Gilchuk, N Kuzmina, PA Ilinykh, K Huang, BM Gunn, A Bryan, ... Immunity 49 (2), 363-374. e10, 2018 | 74 | 2018 |
| Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2–MPER region AI Flyak, N Kuzmina, CD Murin, C Bryan, E Davidson, P Gilchuk, ... Nature microbiology 3 (6), 670-677, 2018 | 74 | 2018 |
| The marburgvirus-neutralizing human monoclonal antibody MR191 targets a conserved site to block virus receptor binding LB King, ML Fusco, AI Flyak, PA Ilinykh, K Huang, B Gunn, ... Cell host & microbe 23 (1), 101-109. e4, 2018 | 58 | 2018 |
| Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms MC Mankowski, VJ Kinchen, LN Wasilewski, AI Flyak, SC Ray, ... Proceedings of the National Academy of Sciences 115 (1), E82-E91, 2018 | 55 | 2018 |
| Broadly neutralizing antibodies targeting new sites of vulnerability in hepatitis C virus E1E2 MD Colbert, AI Flyak, CO Ogega, VJ Kinchen, G Massaccesi, ... Journal of virology 93 (14), 10.1128/jvi. 02070-18, 2019 | 47 | 2019 |
| Chimeric filoviruses for identification and characterization of monoclonal antibodies PA Ilinykh, X Shen, AI Flyak, N Kuzmina, TG Ksiazek, JE Crowe Jr, ... Journal of virology 90 (8), 3890-3901, 2016 | 45 | 2016 |
James CroweVanderbilt University Medical Center在 vanderbilt.edu 的电子邮件经过验证
