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Danda Chapagai, PhD
Danda Chapagai, PhD
在 mgh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Peptidomimetic Polo‐Box‐Targeted Inhibitors that Engage PLK1 in Tumor Cells and Are Selective against the PLK3 Tumor Suppressor
M Baxter, D Chapagai, S Craig, C Hurtado, J Varghese, E Nurmemmedov, ...
ChemMedChem 15 (12), 1058-1066, 2020
152020
Biotic and abiotic stress signaling mediated by salicylic acid
D Kumar, D Chapagai, P Dean, M Davenport
Elucidation of Abiotic Stress Signaling in Plants: Functional Genomics …, 2015
152015
Nonpeptidic, polo-box domain-targeted inhibitors of plk1 block kinase activity, induce its degradation and target-resistant cells
D Chapagai, G Ramamoorthy, J Varghese, E Nurmemmedov, C McInnes, ...
Journal of medicinal chemistry 64 (14), 9916-9925, 2021
142021
Hormone signaling: current perspectives on the roles of salicylic acid and its derivatives in plants
D Kumar, I Haq, D Chapagai, D Tripathi, D Donald, M Hossain, S Devaiah
The Formation, Structure and Activity of Phytochemicals, 115-136, 2015
142015
Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE
SN Craig, M Baxter, D Chapagai, JM Stafford, E Nurmemmedov, ...
European journal of medicinal chemistry 227, 113926, 2022
112022
Structural Basis for Variations in Polo-like Kinase 1 Conformation and Intracellular Stability Induced by ATP-Competitive and Novel Noncompetitive Abbapolin Inhibitors
D Chapagai, G Merhej, C McInnes, MD Wyatt
ACS Chemical Biology 18 (7), 1642-1652, 2023
72023
Biochemical Characterization of SBIP-470 and its role in SA-mediated Signaling in Plants
DP Chapagai
East Tennessee State University, 2014
32014
Abbapolins as inhibitors and degraders of polo-like kinases
C McInnes, MD Wyatt, DP Chapagai, JM Stafford, G Ramamoorthy
US Patent App. 18/304,048, 2023
2023
Development of abbapolin inhibitors of the PLK1 PBD as potential therapeutics for prostate and other challenging cancers
J Stafford, D Chapagai, G Merhej, J Pressley, C Nageswara-Rao, M Wyatt, ...
Cancer Research 83 (7_Supplement), 4993-4993, 2023
2023
A novel strategy for PLK1 kinase inhibition by allosterically targeting the Polo Box Domain
D Chapagai, M Baxter, S Craig, G Ramamoorthy, J Stafford, S Vitali, ...
Cancer Research 82 (12_Supplement), 2572-2572, 2022
2022
Abbapolins as inhibitors and degraders of polo-like kinases
MDW Danda Chapagai, Guru Ramamoorthy, C McInnes, J Varghese
US Patent App. 63/332,919, 2022
2022
Discovery and Mechanistic Study of Novel PBD-Targeted Inhibitors of PLK1 for Prostate Cancer Treatment
DP Chapagai
2022
Converting high affinity peptides to non-peptidic inhibitors via REPLACE: Novel and new strategies in targeting PLK1 Polo Box Domain (PBD) for anti-cancer therapy
D Chapagai, G Ramamoorthy, M Baxter, S Craig, E Nurmemmedov, ...
Cancer Research 81 (13_Supplement), 1241-1241, 2021
2021
Selective polo-like kinase 1 PBD inhibitor
DP Chapagai, M Baxter, G Ramamoorthy, C McInnes, M Wyatt
Cancer Research 79 (13_Supplement), 4712-4712, 2019
2019
PAK6 localizes to centrosome and modulates centrosome homeostasis
H Jia, D Chapagai, J Mallow, MD Perttunen, V Iragavarapu, J Wei, ML Lu
Cancer Research 78 (13_Supplement), 3453-3453, 2018
2018
Involvement of a Putative Lipid Transfer Protein, SBIP-470 in SA-Mediated Signaling
DP Chapagai, DK David Donald, Bingqing Zhao
52nd Annual Meeting of the Phytochemical Society of North America, 2013
2013
Characterization of a putative lipid transfer protein and its role in stress signaling of plants
T Audam, DP Chapagain, D Kumar
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