cGAS–STING drives the IL-6-dependent survival of chromosomally instable cancers C Hong, M Schubert, AE Tijhuis, M Requesens, M Roorda, ... Nature 607 (7918), 366-373, 2022 | 200 | 2022 |
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy MR Ippolito, V Martis, S Martin, AE Tijhuis, C Hong, R Wardenaar, ... Developmental cell 56 (17), 2440-2454. e6, 2021 | 132 | 2021 |
The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity AE Tijhuis, SC Johnson, SE McClelland Molecular cytogenetics 12 (1), 1-21, 2019 | 122 | 2019 |
Genetic instability from a single S phase after whole-genome duplication S Gemble, R Wardenaar, K Keuper, N Srivastava, M Nano, AS Macé, ... Nature 604 (7904), 146-151, 2022 | 94 | 2022 |
Transient genomic instability drives tumorigenesis through accelerated clonal evolution O Shoshani, B Bakker, L de Haan, AE Tijhuis, Y Wang, DH Kim, ... Genes & development 35 (15-16), 1093-1108, 2021 | 66 | 2021 |
The cGAS paradox: contrasting roles for cGAS-STING pathway in chromosomal instability C Hong, AE Tijhuis, F Foijer Cells 8 (10), 1228, 2019 | 58 | 2019 |
Centrosome defects cause microcephaly by activating the 53BP1‐USP28‐TP53 mitotic surveillance pathway TP Phan, AL Maryniak, CA Boatwright, J Lee, A Atkins, A Tijhuis, ... The EMBO Journal 40 (1), e106118, 2021 | 54 | 2021 |
Short-term molecular consequences of chromosome mis-segregation for genome stability L Garribba, G De Feudis, V Martis, M Galli, M Dumont, Y Eliezer, ... Nature Communications 14 (1), 1353, 2023 | 35 | 2023 |
Cancer tolerance to chromosomal instability is driven by Stat1 inactivation in vivo M Schubert, C Hong, LJ Jilderda, MR Rueda, AE Tijhuis, JE Simon, ... bioRxiv, 2021 | 9 | 2021 |
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition CR Gliech, ZY Yeow, D Tapias-Gomez, Y Yang, Z Huang, AE Tijhuis, ... The EMBO Journal 43 (5), 666-694, 2024 | 8 | 2024 |
Extra centrosomes delay DNA damage–driven tumorigenesis VZ Braun, G Karbon, F Schuler, MA Schapfl, JG Weiss, PY Petermann, ... Science Advances 10 (13), eadk0564, 2024 | 4 | 2024 |
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization A Scelfo, V Barra, N Abdennur, G Spracklin, F Busato, C Salinas-Luypaert, ... Journal of Cell Biology 223 (4), e202307026, 2024 | 4 | 2024 |
Tunable DNMT1 degradation reveals cooperation of DNMT1 and DNMT3B in regulating DNA methylation dynamics and genome organization A Scelfo, V Barra, N Abdennur, G Spracklin, F Busato, C Salinas-Luypaert, ... bioRxiv, 2023.05. 04.539406, 2023 | 2 | 2023 |
Mechanisms of genetic instability in a single S-phase following whole genome doubling S Gemble, S Bernhard, N Srivastava, R Wardenaar, M Nano, AS Macé, ... | 2 | 2021 |
Chronic spindle assembly checkpoint activation causes myelosuppression and gastrointestinal atrophy G Karbon, F Schuler, VZ Braun, F Eichin, M Haschka, M Drach, R Sotillo, ... EMBO reports, 1-30, 2024 | | 2024 |
Characterizing chromosomal instability-driven cancer evolution and cell fitness at a glance AE Tijhuis, F Foijer Journal of Cell Science 137 (1), 2024 | | 2024 |
Centrosome amplification primes for apoptosis and favors the response to chemotherapy in ovarian cancer beyond multipolar divisions F Edwards, G Fantozzi, AY Simon, JP Morretton, A Herbette, AE Tijhuis, ... bioRxiv, 2023.07. 28.550973, 2023 | | 2023 |