Intracellular delivery of bioactive AZT nucleotides by aryl phosphate derivatives of AZT C McGuigan, RN Pathirana, J Balzarini, E De Clercq Journal of Medicinal Chemistry 36 (8), 1048-1052, 1993 | 340 | 1993 |
Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT C McGuigan, RN Pathirana, N Mahmood, KG Devine, AJ Hay Antiviral research 17 (4), 311-321, 1992 | 231 | 1992 |
Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine D Saboulard, L Naesens, D Cahard, A Salgado, R Pathirana, ... Molecular Pharmacology 56 (4), 693-704, 1999 | 189 | 1999 |
Evaluation of antibacterial activity of different mangrove plant extracts PD Abeysinghe, RN Pathirana, RP Wanigatunge Ruhuna journal of science 1 (1), 2012 | 97 | 2012 |
Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus C McGuigan, RN Pathirana, M Migliore, R Adak, G Luoni, AT Jones, ... Journal of antimicrobial chemotherapy 60 (6), 1316-1330, 2007 | 96 | 2007 |
Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic … C McGuigan, RN Pathirana, R Snoeck, G Andrei, E De Clercq, J Balzarini Journal of medicinal chemistry 47 (7), 1847-1851, 2004 | 79 | 2004 |
Aryl phosphate derivates of AZT inhibit HIV replication in cells where the nucleoside is poorly active C McGuigan, RN Pathirana, N Mahmood, AJ Hay Bioorganic & medicinal chemistry letters 2 (7), 701-704, 1992 | 62 | 1992 |
Furano pyrimidines as novel potent and selective anti-VZV agents C McGuigan, A Brancale, H Barucki, S Srinivasan, G Jones, R Pathirana, ... Antiviral Chemistry and Chemotherapy 12 (2), 77-89, 2001 | 47 | 2001 |
Diaryl phosphate derivatives act as pro-drugs of AZT with reduced cytotoxicity compared to the parent nucleoside C McGuigan, RN Pathirana, MPH Davies, J Balzarini, E De Clercq Bioorganic & Medicinal Chemistry Letters 4 (3), 427-430, 1994 | 35 | 1994 |
Phosphoramidate derivatives of AZT as inhibitors of HIV: studies on the carboxyl terminus C McGuigan, RN Pathirana, SSM Choi, D Kinchington, TJ O'Connor Antiviral Chemistry and Chemotherapy 4 (2), 97-101, 1993 | 33 | 1993 |
Synthesis and anti-HIV activity of some novel diaryl phosphate derivatives of AZT C McGuigan, M Davies, R Pathirana, N Mahmood, AJ Hay Antiviral research 24 (1), 69-77, 1994 | 30 | 1994 |
Evaluation of invitro sun screen activities of salt marshy plants Suaeda monoica, Suaeda maritima and Halosarcia indica. WD Ratnasooriya, RN Pathirana, AS Dissanayake, BLC Samanmali, ... International Journal of Pharmaceutical Research & Allied Sciences 5 (2), 2016 | 28 | 2016 |
Anti-Varicella—Zoster Virus Bicyclic Nucleosides: Replacement of Furo by Pyrro Base Reduces Antiviral Potency C McGuigan, RN Pathirana, G Jones, G Andrei, R Snoeck, E De Clercq, ... Antiviral Chemistry and Chemotherapy 11 (5), 343-348, 2000 | 24 | 2000 |
Novel Antiviral Activity of l-Dideoxy Bicyclic Nucleoside Analogues versus Vaccinia and Measles Viruses in Vitro C McGuigan, K Hinsinger, L Farleigh, RN Pathirana, JJ Bugert Journal of Medicinal Chemistry 56 (3), 1311-1322, 2013 | 23 | 2013 |
Antibacterial activity of water extracts of different parts of Morinda citrifolia grown in Sri Lanka CB Ranaweera, R Pathirana, WD Ratnasooriya | 20 | 2016 |
Evaluation of in vitro antibacterial activity of some Sri Lankan medicinal plants DMRK Dissanayake, CB Ranaweera, R Pathirana, WD Ratnasooriya International Journal of Pharmaceutical Research and Allied Sciences 4 (2 …, 2015 | 12 | 2015 |
Antibacterial activity of aqueous root, seed, flower and stem bark extracts of Acronychia pedunculata grown in Sri Lanka CB Ranaweera, R Pathirana, WD Ratnasooriya | 5 | 2016 |
Reactions of 4, 8-dimethylbicyclo [3.3. 1] nona-3, 7-diene-2, 6-dione and of 4, 6-dimethylbicyclo [3.3. 1] nona-3, 6-diene-2, 8-dione with hydroxylamine and with hydrazines JM Mellor, R Pathirana, JHA Stibbard Journal of the Chemical Society, Perkin Transactions 1, 2541-2544, 1983 | 5 | 1983 |
Transformations of 4, 9-dimethyl-2, 3, 7, 8-tetra-azatetracyclo [7.3. 1.0. 4, 12 0 6, 10] trideca-1, 6-diene, a bishydrazone having two bridgehead double bonds JM Mellor, R Pathirana Journal of the Chemical Society, Perkin Transactions 1, 2545-2549, 1983 | 5 | 1983 |
Pre-clinical development of the BCNAs: The most potent anti-VZV agents reported to date C McGuigan, R Pathirana, M Migliore, R Adak, A Angell, G Henson, ... Antiviral research, 70 70 (1), A31-A31, 2006 | 2 | 2006 |