A complex secretory program orchestrated by the inflammasome controls paracrine senescence JC Acosta, A Banito, T Wuestefeld, A Georgilis, P Janich, JP Morton, ... Nature cell biology 15 (8), 978-990, 2013 | 1969 | 2013 |
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development TW Kang, T Yevsa, N Woller, L Hoenicke, T Wuestefeld, D Dauch, ... Nature 479 (7374), 547-551, 2011 | 1575 | 2011 |
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype N Herranz, S Gallage, M Mellone, T Wuestefeld, S Klotz, CJ Hanley, ... Nature cell biology 17 (9), 1205-1217, 2015 | 687 | 2015 |
Met provides essential signals for liver regeneration M Borowiak, AN Garratt, T Wüstefeld, M Strehle, C Trautwein, ... Proceedings of the National Academy of Sciences 101 (29), 10608-10613, 2004 | 649 | 2004 |
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles S Walz, F Lorenzin, J Morton, KE Wiese, B von Eyss, S Herold, L Rycak, ... Nature 511 (7510), 483-487, 2014 | 512 | 2014 |
A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage J Wang, Q Sun, Y Morita, H Jiang, A Groß, A Lechel, K Hildner, ... Cell 148 (5), 1001-1014, 2012 | 378 | 2012 |
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer R Rudalska, D Dauch, T Longerich, K McJunkin, T Wuestefeld, TW Kang, ... Nature medicine 20 (10), 1138-1146, 2014 | 304 | 2014 |
Deregulated MYC expression induces dependence upon AMPK-related kinase 5 L Liu, J Ulbrich, J Müller, T Wüstefeld, L Aeberhard, TR Kress, ... Nature 483 (7391), 608-612, 2012 | 299 | 2012 |
A MYC–aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer D Dauch, R Rudalska, G Cossa, JC Nault, TW Kang, T Wuestefeld, ... Nature medicine 22 (7), 744-753, 2016 | 279 | 2016 |
Mediators of inflammation and acute phase response in the liver. KL Streetz, T Wüstefeld, C Klein, MP Manns, C Trautwein Cellular and molecular biology (Noisy-le-Grand, France) 47 (4), 661-673, 2001 | 272 | 2001 |
Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA C Klein, CT Bock, H Wedemeyer, T Wüstefeld, S Locarnini, HP Dienes, ... Gastroenterology 125 (1), 9-18, 2003 | 254 | 2003 |
The IL-6–gp130–STAT3 pathway in hepatocytes triggers liver protection in T cell–mediated liver injury C Klein, T Wüstefeld, U Assmus, T Roskams, S Rose-John, M Müller, ... The Journal of clinical investigation 115 (4), 860-869, 2005 | 248 | 2005 |
A critical role for notch signaling in the formation of cholangiocellular carcinomas S Zender, I Nickeleit, T Wuestefeld, I Sörensen, D Dauch, P Bozko, ... Cancer cell 23 (6), 784-795, 2013 | 240 | 2013 |
Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury T Luedde, U Assmus, T Wüstefeld, AM zu Vilsendorf, T Roskams, ... The Journal of clinical investigation 115 (4), 849-859, 2005 | 221 | 2005 |
Interleukin-6/glycoprotein 130-dependent pathways are protective during liver regeneration T Wuestefeld, C Klein, KL Streetz, U Betz, J Lauber, J Buer, MP Manns, ... Journal of Biological Chemistry 278 (13), 11281-11288, 2003 | 218 | 2003 |
Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases KL Streetz, F Tacke, L Leifeld, T Wüstefeld, A Graw, C Klein, K Kamino, ... Hepatology 38 (1), 218-229, 2003 | 215 | 2003 |
Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells A Satyanarayana, SU Wiemann, J Buer, J Lauber, KEJ Dittmar, ... The EMBO journal 22 (15), 4003-4013, 2003 | 197 | 2003 |
High adiponectin in chronic liver disease and cholestasis suggests biliary route of adiponectin excretion in vivo F Tacke, T Wüstefeld, R Horn, T Luedde, AS Rao, MP Manns, C Trautwein, ... Journal of hepatology 42 (5), 666-673, 2005 | 172 | 2005 |
A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration T Wuestefeld, M Pesic, R Rudalska, D Dauch, T Longerich, TW Kang, ... Cell 153 (2), 389-401, 2013 | 167 | 2013 |
Hyperstimulation with interleukin 6 inhibits cell cycle progression after hepatectomy in mice T Wüstefeld, T Rakemann, S Kubicka, MP Manns, C Trautwein Hepatology 32 (3), 514-522, 2000 | 137 | 2000 |