Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 6862 | 2014 |
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies BK Bulik-Sullivan, PR Loh, HK Finucane, S Ripke, J Yang, ... Nature genetics 47 (3), 291-295, 2015 | 3609 | 2015 |
Schizophrenia risk from complex variation of complement component 4 A Sekar, AR Bialas, H De Rivera, A Davis, TR Hammond, N Kamitaki, ... Nature 530 (7589), 177-183, 2016 | 2125 | 2016 |
Partitioning heritability by functional annotation using genome-wide association summary statistics HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ... Nature genetics 47 (11), 1228-1235, 2015 | 1889 | 2015 |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia S Ripke, C O'dushlaine, K Chambert, JL Moran, AK Kähler, S Akterin, ... Nature genetics 45 (10), 1150-1159, 2013 | 1694 | 2013 |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection AF Pardiñas, P Holmans, AJ Pocklington, V Escott-Price, S Ripke, ... Nature genetics 50 (3), 381, 2018 | 1328 | 2018 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1205 | 2018 |
Modeling linkage disequilibrium increases accuracy of polygenic risk scores BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ... The american journal of human genetics 97 (4), 576-592, 2015 | 1161 | 2015 |
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ... Cell 179 (7), 1469-1482. e11, 2019 | 881 | 2019 |
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects CR Marshall, DP Howrigan, D Merico, B Thiruvahindrapuram, W Wu, ... Nature Genetics, 2017 | 806 | 2017 |
Treatment-resistant schizophrenia: treatment response and resistance in psychosis (TRRIP) working group consensus guidelines on diagnosis and terminology OD Howes, R McCutcheon, O Agid, A De Bartolomeis, NJM Van Beveren, ... American Journal of Psychiatry 174 (3), 216-229, 2017 | 769 | 2017 |
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ... The American Journal of Human Genetics 95 (5), 535-552, 2014 | 609 | 2014 |
Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 566 | 2022 |
Integrative functional genomic analysis of human brain development and neuropsychiatric risks M Li, G Santpere, Y Imamura Kawasawa, OV Evgrafov, FO Gulden, ... Science 362 (6420), eaat7615, 2018 | 521 | 2018 |
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ... Nature genetics 53 (6), 817-829, 2021 | 469 | 2021 |
Genetic identification of brain cell types underlying schizophrenia NG Skene, J Bryois, TE Bakken, G Breen, JJ Crowley, HA Gaspar, ... Nature genetics 50 (6), 825-833, 2018 | 469 | 2018 |
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ... Cell 173 (7), 1705-1715. e16, 2018 | 452 | 2018 |
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis PR Loh, G Bhatia, A Gusev, HK Finucane, BK Bulik-Sullivan, SJ Pollack, ... Nature genetics 47 (12), 1385-1392, 2015 | 450 | 2015 |
Analysis of copy number variations at 15 schizophrenia-associated loci E Rees, JTR Walters, L Georgieva, AR Isles, KD Chambert, AL Richards, ... The British Journal of Psychiatry 204 (2), 108-114, 2014 | 421 | 2014 |
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders T Singh, MI Kurki, D Curtis, SM Purcell, L Crooks, J McRae, J Suvisaari, ... Nature neuroscience 19 (4), 571-577, 2016 | 399 | 2016 |