Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death T Nakagawa, S Shimizu, T Watanabe, O Yamaguchi, K Otsu, H Yamagata, ... Nature 434 (7033), 652-658, 2005 | 1901 | 2005 |
SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle T Nakagawa, DJ Lomb, MC Haigis, L Guarente Cell 137 (3), 560-570, 2009 | 913 | 2009 |
Sirtuins at a glance T Nakagawa, L Guarente Journal of cell science 124 (6), 833-838, 2011 | 389 | 2011 |
Mitochondrial membrane permeability transition and cell death Y Tsujimoto, T Nakagawa, S Shimizu Biochimica et Biophysica Acta (BBA)-Bioenergetics 1757 (9-10), 1297-1300, 2006 | 245 | 2006 |
NAD metabolism: Implications in aging and longevity K Yaku, K Okabe, T Nakagawa Ageing research reviews 47, 1-17, 2018 | 244 | 2018 |
SIRT1-mediated eNAMPT secretion from adipose tissue regulates hypothalamic NAD+ and function in mice MJ Yoon, M Yoshida, S Johnson, A Takikawa, I Usui, K Tobe, ... Cell metabolism 21 (5), 706-717, 2015 | 231 | 2015 |
Implications of altered NAD metabolism in metabolic disorders K Okabe, K Yaku, K Tobe, T Nakagawa Journal of biomedical science 26 (1), 34, 2019 | 217 | 2019 |
CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors A Nawaz, A Aminuddin, T Kado, A Takikawa, S Yamamoto, K Tsuneyama, ... Nature communications 8 (1), 286, 2017 | 217 | 2017 |
NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion Y Sasaki, T Nakagawa, X Mao, A DiAntonio, J Milbrandt elife 5, e19749, 2016 | 201 | 2016 |
NAD metabolism in cancer therapeutics K Yaku, K Okabe, K Hikosaka, T Nakagawa Frontiers in Oncology 8, 622, 2018 | 198 | 2018 |
Hemangioma of the nasal cavity: a clinicopathologic study N Iwata, K Hattori, T Nakagawa, T Tsujimura Auris nasus larynx 29 (4), 335-339, 2002 | 116 | 2002 |
Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway Y Nishida, A Nawaz, T Kado, A Takikawa, Y Igarashi, Y Onogi, T Wada, ... Journal of cachexia, sarcopenia and muscle 11 (1), 241-258, 2020 | 107 | 2020 |
HIF-1α in myeloid cells promotes adipose tissue remodeling toward insulin resistance A Takikawa, A Mahmood, A Nawaz, T Kado, K Okabe, S Yamamoto, ... Diabetes 65 (12), 3649-3659, 2016 | 106 | 2016 |
Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice T Sasaki, O Kikuchi, M Shimpuku, VY Susanti, H Yokota-Hashimoto, ... Diabetologia 57, 819-831, 2014 | 104 | 2014 |
Deficiency of nicotinamide mononucleotide adenylyltransferase 3 (nmnat3) causes hemolytic anemia by altering the glycolytic flow in mature erythrocytes K Hikosaka, M Ikutani, M Shito, K Kazuma, M Gulshan, Y Nagai, ... Journal of Biological Chemistry 289 (21), 14796-14811, 2014 | 91 | 2014 |
Urea cycle regulation by mitochondrial sirtuin, SIRT5 T Nakagawa, L Guarente Aging 1 (6), 578-581, 2009 | 85 | 2009 |
Nmnat3 is dispensable in mitochondrial NAD level maintenance in vivo M Yamamoto, K Hikosaka, A Mahmood, K Tobe, H Shojaku, H Inohara, ... PloS one 11 (1), e0147037, 2016 | 84 | 2016 |
SnapShot: sirtuins, NAD, and aging T Nakagawa, L Guarente Cell metabolism 20 (1), 192-192. e1, 2014 | 75 | 2014 |
A Bax/Bak-independent mechanism of cytochrome c release T Mizuta, S Shimizu, Y Matsuoka, T Nakagawa, Y Tsujimoto Journal of Biological Chemistry 282 (22), 16623-16630, 2007 | 69 | 2007 |
Bofutsushosan improves gut barrier function with a bloom of Akkermansia muciniphila and improves glucose metabolism in mice with diet-induced obesity S Fujisaka, I Usui, A Nawaz, Y Igarashi, K Okabe, Y Furusawa, ... Scientific Reports 10 (1), 5544, 2020 | 66 | 2020 |