Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity O Gross, A Gewies, K Finger, M Schäfer, T Sparwasser, C Peschel, ... Nature 442 (7103), 651-656, 2006 | 1004 | 2006 |
Minor lesion mutational spectrum of the entire NF1 gene does not explain its high mutability but points to a functional domain upstream of the GAP-related domain R Fahsold, S Hoffmeyer, C Mischung, C Gille, C Ehlers, N Kücükceylan, ... The American Journal of Human Genetics 66 (3), 790-818, 2000 | 399 | 2000 |
Inhibition of MALT1 protease activity is selectively toxic for activated B cell–like diffuse large B cell lymphoma cells U Ferch, B Kloo, A Gewies, V Pfänder, M Düwel, C Peschel, ... Journal of Experimental Medicine 206 (11), 2313-2320, 2009 | 217 | 2009 |
Introduction to apoptosis A Gewies Apo Review 3 (1), 1-26, 2003 | 198 | 2003 |
Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death K Neumann, M Castineiras-Vilarino, U Höckendorf, N Hannesschläger, ... Immunity 40 (3), 389-399, 2014 | 193 | 2014 |
Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1 (NF1) A Klose, M Reza Ahmadian, M Schuelke, K Scheffzek, S Hoffmeyer, ... Human molecular genetics 7 (8), 1261-1268, 1998 | 193 | 1998 |
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma K Pechloff, J Holch, U Ferch, M Schweneker, K Brunner, M Kremer, ... Journal of Experimental Medicine 207 (5), 1031-1044, 2010 | 181 | 2010 |
Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-κB pathway and promotes lymphomagenesis C Homig-Holzel, C Hojer, J Rastelli, S Casola, LJ Strobl, W Müller, ... The Journal of experimental medicine 205 (6), 1317-1329, 2008 | 177 | 2008 |
Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation A Gewies, O Gorka, H Bergmann, K Pechloff, F Petermann, KM Jeltsch, ... Cell reports 9 (4), 1292-1305, 2014 | 157 | 2014 |
A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency HH Jabara, T Ohsumi, J Chou, MJ Massaad, H Benson, A Megarbane, ... Journal of allergy and clinical immunology 132 (1), 151-158, 2013 | 154 | 2013 |
The CARD11-BCL10-MALT1 (CBM) signalosome complex: stepping into the limelight of human primary immunodeficiency SE Turvey, A Durandy, A Fischer, SY Fung, RS Geha, A Gewies, T Giese, ... Journal of Allergy and Clinical Immunology 134 (2), 276-284, 2014 | 147 | 2014 |
Spike, a novel BH3‐only protein, regulates apoptosis at the endoplasmic reticulum T Mund, A Gewies, N Schoenfeld, MKA Bauer, S Grimm The FASEB Journal 17 (6), 696-698, 2003 | 112 | 2003 |
Alternative splicing of MALT1 controls signalling and activation of CD4+ T cells I Meininger, RA Griesbach, D Hu, T Gehring, T Seeholzer, A Bertossi, ... Nature communications 7 (1), 11292, 2016 | 102 | 2016 |
MALT1 directs B cell receptor–induced canonical nuclear factor-κB signaling selectively to the c-Rel subunit U Ferch, CM Büschenfelde, A Gewies, E Wegener, S Rauser, C Peschel, ... Nature immunology 8 (9), 984-991, 2007 | 92 | 2007 |
p53 is involved in tumor necrosis factor-α-induced apoptosis in the human prostatic carcinoma cell line LNCaP OW Rokhlin, AV Gudkov, S Kwek, RA Glover, AS Gewies, MB Cohen Oncogene 19 (15), 1959-1968, 2000 | 85 | 2000 |
Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells M Rosenbaum, A Gewies, K Pechloff, C Heuser, T Engleitner, T Gehring, ... Nature communications 10 (1), 2352, 2019 | 69 | 2019 |
UBP41 is a proapoptotic ubiquitin-specific protease A Gewies, S Grimm Cancer research 63 (3), 682-688, 2003 | 60 | 2003 |
Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy B Kong, P Bruns, NA Behler, L Chang, AM Schlitter, J Cao, A Gewies, ... Gut 67 (1), 146-156, 2018 | 57 | 2018 |
Cytochrome c is involved in Fas-mediated apoptosis of prostatic carcinoma cell lines A Gewies, OW Rokhlin, MB Cohen Cancer research 60 (8), 2163-2168, 2000 | 52 | 2000 |
Analysis of the NF1 gene by temperature gradient gel electrophoresis reveals a high incidence of mutations in exon 4b MR Toliat, F Erdogan, A Gewies, R Fahsold, A Buske, S Tinschert, ... ELECTROPHORESIS: An International Journal 21 (3), 541-544, 2000 | 46 | 2000 |