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Irene Mencía Castaño
Irene Mencía Castaño
PhD
在 rcsi.ie 的电子邮件经过验证
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Translating the role of osteogenic-angiogenic coupling in bone formation: Highly efficient chitosan-pDNA activated scaffolds can accelerate bone regeneration in critical-sized …
RM Raftery, IM Castaño, G Chen, B Cavanagh, B Quinn, CM Curtin, ...
Biomaterials 149, 116-127, 2017
1242017
Delivering nucleic‐acid based nanomedicines on biomaterial scaffolds for orthopedic tissue repair: Challenges, progress and future perspectives
RM Raftery, DP Walsh, IM Castaño, A Heise, GP Duffy, SA Cryan, ...
Advanced Materials 28 (27), 5447-5469, 2016
1082016
A novel collagen-nanohydroxyapatite microRNA-activated scaffold for tissue engineering applications capable of efficient delivery of both miR-mimics and antagomiRs to human …
IM Castaño, CM Curtin, G Shaw, JM Murphy, GP Duffy, FJ O'Brien
Journal of controlled release 200, 42-51, 2015
952015
Next generation bone tissue engineering: non-viral miR-133a inhibition using collagen-nanohydroxyapatite scaffolds rapidly enhances osteogenesis
I Mencía Castaño, CM Curtin, GP Duffy, FJ O’Brien
Scientific Reports 6 (1), 27941, 2016
902016
Delivery of the improved BMP-2-Advanced plasmid DNA within a gene-activated scaffold accelerates mesenchymal stem cell osteogenesis and critical size defect repair
RM Raftery, I Mencía-Castaño, S Sperger, G Chen, B Cavanagh, ...
Journal of controlled release 283, 20-31, 2018
802018
Scaffold‐based microRNA therapies in regenerative medicine and cancer
CM Curtin, IM Castaño, FJ O'Brien
Advanced healthcare materials 7 (1), 1700695, 2018
692018
Highly versatile cell-penetrating peptide loaded scaffold for efficient and localised gene delivery to multiple cell types: From development to application in tissue engineering
RM Raftery, DP Walsh, LB Ferreras, IM Castaño, G Chen, M LeMoine, ...
Biomaterials 216, 119277, 2019
602019
Harnessing an inhibitory role of miR-16 in osteogenesis by human mesenchymal stem cells for advanced scaffold-based bone tissue engineering
I Mencía Castaño, CM Curtin, GP Duffy, FJ O'Brien
Tissue Engineering Part A 25 (1-2), 24-33, 2019
422019
Rapid bone repair with the recruitment of CD206+ M2-like macrophages using non-viral scaffold-mediated miR-133a inhibition of host cells
IM Castaño, RM Raftery, G Chen, B Cavanagh, B Quinn, GP Duffy, ...
Acta biomaterialia 109, 267-279, 2020
412020
Nanoparticle-mediated siRNA delivery assessed in a 3D co-culture model simulating prostate cancer bone metastasis
KA Fitzgerald, J Guo, RM Raftery, IM Castano, CM Curtin, M Gooding, ...
International journal of pharmaceutics 511 (2), 1058-1069, 2016
362016
Transfection of autologous host cells in vivo using gene activated collagen scaffolds incorporating star-polypeptides
DP Walsh, RM Raftery, IM Castaño, R Murphy, B Cavanagh, A Heise, ...
Journal of Controlled Release 304, 191-203, 2019
352019
Collagen/GAG scaffolds activated by RALA-siMMP-9 complexes with potential for improved diabetic foot ulcer healing
LP Yan, IM Castano, R Sridharan, D Kelly, M Lemoine, BL Cavanagh, ...
Materials Science and Engineering: C 114, 111022, 2020
272020
Dual scaffold delivery of miR-210 mimic and miR-16 inhibitor enhances angiogenesis and osteogenesis to accelerate bone healing
IM Castaño, RM Raftery, G Chen, B Cavanagh, B Quinn, GP Duffy, ...
Acta Biomaterialia 172, 480-493, 2023
82023
microRNA modulation
I Mencía Castaño, RM Raftery, CM Curtin, J Grillari, H Redl, FJ O’Brien
Cell Engineering and Regeneration, 511-576, 2020
62020
COUPLING ANGIOGENESIS AND OSTEOGENESIS FOR ENHANCED IN VIVO BONE REPAIR USING SCAFFOLDS AND COMBINATORIAL MICRORNA THERAPY
CM Curtin, IM Castano, RM Raftery, G Chen, B Cavanagh, B Quinn, ...
TISSUE ENGINEERING PART A 28, S456-S456, 2022
2022
Corrigendum to" Transfection of autologous host cells in vivo using gene activated collagen scaffolds incorporating star-polypeptides"[J. Control. Release 304 (2019) 191-203]
DP Walsh, RM Raftery, IM Castaño, R Murphy, B Cavanagh, A Heise, ...
Journal of controlled release: official journal of the Controlled Release …, 2020
2020
Development of a microRNA Delivery Scaffold System for Bone Tissue Engineering
IM Castaño
Royal College of Surgeons in Ireland, 2015
2015
Nanohydroxyapatite-based microRNA delivery on Collagen-nanohydroxyapatite Scaffolds for Bone Tissue Engineering
I Mencía Castaño, CM Curtin, GP Duffy, FJ O’Brien
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