Autoantibodies against type I IFNs in patients with life-threatening COVID-19 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 2629 | 2020 |
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 2256 | 2020 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 501 | 2021 |
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 368 | 2021 |
Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1 P Bastard, E Orlova, L Sozaeva, R Lévy, A James, MM Schmitt, S Ochoa, ... Journal of Experimental Medicine 218 (7), 2021 | 259 | 2021 |
Mendelian susceptibility to mycobacterial disease: 2014–2018 update J Rosain, XF Kong, R Martinez‐Barricarte, C Oleaga‐Quintas, ... Immunology and cell biology 97 (4), 360-367, 2019 | 197 | 2019 |
Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine P Bastard, E Michailidis, HH Hoffmann, M Chbihi, T Le Voyer, J Rosain, ... Journal of Experimental Medicine 218 (4), e20202486, 2021 | 167 | 2021 |
Assessing complement blockade in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab R Peffault de Latour, V Fremeaux-Bacchi, R Porcher, A Xhaard, J Rosain, ... Blood, The Journal of the American Society of Hematology 125 (5), 775-783, 2015 | 155 | 2015 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 150 | 2022 |
Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes J Hadjadj, N Aladjidi, H Fernandes, G Leverger, A Magérus-Chatinet, ... Blood, The Journal of the American Society of Hematology 134 (1), 9-21, 2019 | 134 | 2019 |
Inherited human IFN-γ deficiency underlies mycobacterial disease G Kerner, J Rosain, A Guérin, A Al-Khabaz, C Oleaga-Quintas, ... The Journal of clinical investigation 130 (6), 3158-3171, 2020 | 119 | 2020 |
T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency I Brigida, M Zoccolillo, MP Cicalese, L Pfajfer, F Barzaghi, S Scala, ... Blood, The Journal of the American Society of Hematology 132 (22), 2362-2374, 2018 | 116 | 2018 |
Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria R Yang, F Mele, L Worley, D Langlais, J Rosain, I Benhsaien, H Elarabi, ... Cell 183 (7), 1826-1847. e31, 2020 | 115 | 2020 |
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome V Béziat, SJ Tavernier, YH Chen, CS Ma, M Materna, A Laurence, J Staal, ... Journal of Experimental Medicine 217 (6), 2020 | 113 | 2020 |
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children D Lee, J Le Pen, A Yatim, B Dong, Y Aquino, M Ogishi, R Pescarmona, ... Science 379 (6632), eabo3627, 2022 | 99 | 2022 |
Homozygous STAT2 gain-of-function mutation by loss of USP18 activity in a patient with type I interferonopathy C Gruber, M Martin-Fernandez, F Ailal, X Qiu, J Taft, J Altman, J Rosain, ... Journal of Experimental Medicine 217 (5), 2020 | 99 | 2020 |
Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency P Bastard, J Manry, J Chen, J Rosain, Y Seeleuthner, O AbuZaitun, ... The Journal of clinical investigation 131 (1), 2021 | 94 | 2021 |
Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphic IKBKG/NEMO mutations C Miot, K Imai, C Imai, AJ Mancini, ZY Kucuk, T Kawai, R Nishikomori, ... Blood, The Journal of the American Society of Hematology 130 (12), 1456-1467, 2017 | 93 | 2017 |
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child M Ogishi, R Yang, C Aytekin, D Langlais, M Bourgey, T Khan, FA Ali, ... Nature medicine 27 (9), 1646-1654, 2021 | 92 | 2021 |
HGID Lab; NIAID-USUHS Immune Response to COVID Group; COVID Clinicians; COVID-STORM Clinicians; Imagine COVID Group; French COVID Cohort Study Group; Milieu Intérieur … P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 91 | 2020 |