MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas N Mäkinen, M Mehine, J Tolvanen, E Kaasinen, Y Li, HJ Lehtonen, ... Science 334 (6053), 252-255, 2011 | 743 | 2011 |
CTCF/cohesin-binding sites are frequently mutated in cancer R Katainen, K Dave, E Pitkänen, K Palin, T Kivioja, N Välimäki, AE Gylfe, ... Nature genetics 47 (7), 818-821, 2015 | 460 | 2015 |
Characterization of uterine leiomyomas by whole-genome sequencing M Mehine, E Kaasinen, N Mäkinen, R Katainen, K Kämpjärvi, E Pitkänen, ... New England Journal of Medicine 369 (1), 43-53, 2013 | 355 | 2013 |
Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3 EM Haapaniemi, M Kaustio, HLM Rajala, AJ van Adrichem, L Kainulainen, ... Blood, The Journal of the American Society of Hematology 125 (4), 639-648, 2015 | 295 | 2015 |
The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera V Ahola, R Lehtonen, P Somervuo, L Salmela, P Koskinen, P Rastas, ... Nature communications 5 (1), 4737, 2014 | 241 | 2014 |
Colibactin DNA-damage signature indicates mutational impact in colorectal cancer PJ Dziubańska-Kusibab, H Berger, F Battistini, BAM Bouwman, A Iftekhar, ... Nature medicine 26 (7), 1063-1069, 2020 | 188 | 2020 |
Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer T Cajuso, UA Hänninen, J Kondelin, AE Gylfe, T Tanskanen, R Katainen, ... International journal of cancer 135 (3), 611-623, 2014 | 129 | 2014 |
AIP inactivation leads to pituitary tumorigenesis through defective Gαi-cAMP signaling I Tuominen, E Heliövaara, A Raitila, MR Rautiainen, M Mehine, ... Oncogene 34 (9), 1174-1184, 2015 | 117 | 2015 |
Genetic and epigenetic characteristics of inflammatory bowel Disease–Associated colorectal cancer K Rajamäki, A Taira, R Katainen, N Välimäki, A Kuosmanen, RM Plaketti, ... Gastroenterology 161 (2), 592-607, 2021 | 116 | 2021 |
Eleven candidate susceptibility genes for common familial colorectal cancer AE Gylfe, R Katainen, J Kondelin, T Tanskanen, T Cajuso, U Hänninen, ... PLoS genetics 9 (10), e1003876, 2013 | 98 | 2013 |
Identification of 33 candidate oncogenes by screening for base-specific mutations S Tuupanen, UA Hänninen, J Kondelin, P Von Nandelstadh, T Cajuso, ... British journal of cancer 111 (8), 1657-1662, 2014 | 80 | 2014 |
Exome-wide somatic mutation characterization of small bowel adenocarcinoma UA Hänninen, R Katainen, T Tanskanen, RM Plaketti, R Laine, ... PLoS genetics 14 (3), e1007200, 2018 | 79 | 2018 |
Identification of candidate oncogenes in human colorectal cancers with microsatellite instability AE Gylfe, J Kondelin, M Turunen, H Ristolainen, R Katainen, E Pitkänen, ... Gastroenterology 145 (3), 540-543. e22, 2013 | 77 | 2013 |
Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans E Kaasinen, O Kuismin, K Rajamäki, H Ristolainen, M Aavikko, J Kondelin, ... Nature communications 10 (1), 1252, 2019 | 76 | 2019 |
Systematic analysis of human protein phosphatase interactions and dynamics L Yadav, F Tamene, H Göös, A van Drogen, R Katainen, R Aebersold, ... Cell systems 4 (4), 430-444. e5, 2017 | 73 | 2017 |
Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival T Cajuso, P Sulo, T Tanskanen, R Katainen, A Taira, UA Hänninen, ... Nature communications 10 (1), 4022, 2019 | 68 | 2019 |
Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer E Pitkänen, T Cajuso, R Katainen, E Kaasinen, N Välimäki, K Palin, ... Oncotarget 5 (3), 853, 2014 | 67 | 2014 |
Germline mutations in young non-smoking women with lung adenocarcinoma I Donner, R Katainen, LJ Sipilä, M Aavikko, E Pukkala, LA Aaltonen Lung Cancer 122, 76-82, 2018 | 46 | 2018 |
Discovery of potential causative mutations in human coding and noncoding genome with the interactive software BasePlayer R Katainen, I Donner, T Cajuso, E Kaasinen, K Palin, V Mäkinen, ... Nature Protocols 13 (11), 2580-2600, 2018 | 41 | 2018 |
Contribution of allelic imbalance to colorectal cancer K Palin, E Pitkänen, M Turunen, B Sahu, P Pihlajamaa, T Kivioja, ... Nature communications 9 (1), 3664, 2018 | 35 | 2018 |