High glucose reduces megalin-mediated albumin endocytosis in renal proximal tubule cells through protein kinase B O-GlcNAcylation D de Barros Peruchetti, RP Silva-Aguiar, GM Siqueira, WB Dias, ... Journal of Biological Chemistry 293 (29), 11388-11400, 2018 | 47 | 2018 |
5-Lypoxygenase products are involved in renal tubulointerstitial injury induced by albumin overload in proximal tubules in mice SS Landgraf, LS Silva, DB Peruchetti, GM Sirtoli, F Moraes-Santos, ... PLoS One 9 (10), e107549, 2014 | 38 | 2014 |
Mis-regulation of mammalian target of rapamycin (mTOR) complexes induced by albuminuria in proximal tubules DB Peruchetti, J Cheng, C Caruso-Neves, WB Guggino Journal of Biological Chemistry 289 (24), 16790-16801, 2014 | 38 | 2014 |
LPS induces mTORC1 and mTORC2 activation during monocyte adhesion MC Ribeiro, DB Peruchetti, LS Silva, JL Silva-Filho, MC Souza, ... Frontiers in molecular biosciences 5, 67, 2018 | 28 | 2018 |
(Na++ K+)-ATPase is a target for phosphoinositide 3-kinase/protein kinase B and protein kinase C pathways triggered by albumin DB Peruchetti, AAS Pinheiro, SS Landgraf, M Wengert, CM Takiya, ... Journal of Biological Chemistry 286 (52), 45041-45047, 2011 | 28 | 2011 |
Albumin expands albumin reabsorption capacity in proximal tubule epithelial cells through a positive feedback loop between AKT and megalin RP Silva-Aguiar, DB Peruchetti, LS Florentino, CM Takiya, MP Marzolo, ... International Journal of Molecular Sciences 23 (2), 848, 2022 | 21 | 2022 |
A high salt diet induces tubular damage associated with a pro-inflammatory and pro-fibrotic response in a hypertension-independent manner DE Teixeira, DB Peruchetti, MC Souza, MG das Graças Henriques, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (11), 165907, 2020 | 21 | 2020 |
Interaction between bradykinin B2 and Ang-(1–7) Mas receptors regulates erythrocyte invasion by Plasmodium falciparum L de Souza Silva, D de Barros Peruchetti, CT Ferreira-Da Silva, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (11), 2438-2444, 2016 | 20 | 2016 |
Role of the renin-angiotensin system in the development of severe COVID-19 in hypertensive patients RP Silva-Aguiar, DB Peruchetti, PRM Rocco, AH Schmaier, PMR e Silva, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 319 (4 …, 2020 | 18 | 2020 |
The renin–angiotensin–aldosterone system: Role in pathogenesis and potential therapeutic target in COVID‐19 CL Braga, RP Silva‐Aguiar, D Battaglini, DB Peruchetti, C Robba, ... Pharmacology Research & Perspectives 8 (4), e00623, 2020 | 18 | 2020 |
Eugenol disrupts Plasmodium falciparum intracellular development during the erythrocytic cycle and protects against cerebral malaria KAO Pontes, LS Silva, EC Santos, AS Pinheiro, DE Teixeira, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (3), 129813, 2021 | 17 | 2021 |
IL-4 receptor α chain protects the kidney against tubule-interstitial injury induced by albumin overload DB Peruchetti, JL Silva-Filho, RP Silva-Aguiar, DE Teixeira, CM Takiya, ... Frontiers in Physiology 11, 172, 2020 | 17 | 2020 |
Megalin-mediated albumin endocytosis in renal proximal tubules is involved in the antiproteinuric effect of angiotensin II type 1 receptor blocker in a subclinical acute kidney … DB Peruchetti, PFR Barahuna-Filho, RP Silva-Aguiar, TP Abreu, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (9), 129950, 2021 | 16 | 2021 |
The angiotensin II/AT1 receptor pathway mediates malaria-induced acute kidney injury LS Silva, DB Peruchetti, RP Silva-Aguiar, TP Abreu, BKA Dal-Cheri, ... PLoS One 13 (9), e0203836, 2018 | 16 | 2018 |
Uroguanylin modulates (Na++ K+) ATPase in a proximal tubule cell line: Interactions among the cGMP/protein kinase G, cAMP/protein kinase A, and mTOR pathways FJ Arnaud-Batista, DB Peruchetti, TP Abreu, NRF do Nascimento, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (7), 1431-1438, 2016 | 16 | 2016 |
Lithium ameliorates tubule-interstitial injury through activation of the mTORC2/protein kinase B pathway DE Teixeira, DB Peruchetti, LS Silva, RP Silva-Aguiar, MB Oquendo, ... PLoS One 14 (4), e0215871, 2019 | 15 | 2019 |
Kinins Released by Erythrocytic Stages of Plasmodium falciparum Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier … LS Silva, AS Pinheiro, DE Teixeira, RP Silva-Aguiar, DB Peruchetti, ... Frontiers in Medicine 6, 75, 2019 | 14 | 2019 |
Subclinical acute kidney injury in COVID-19: possible mechanisms and future perspectives RP Silva-Aguiar, DE Teixeira, RAS Peres, DB Peruchetti, CP Gomes, ... International Journal of Molecular Sciences 23 (22), 14193, 2022 | 12 | 2022 |
PKB is a central molecule in the modulation of Na+-ATPase activity by albumin in renal proximal tubule cells DB Peruchetti, AC Freitas, VC Pereira, JV Lopes, CM Takiya, ... Archives of Biochemistry and Biophysics 674, 108115, 2019 | 10 | 2019 |
Inhibition of SGLT2 co-transporter by dapagliflozin ameliorates tubular proteinuria and tubule-interstitial injury at the early stage of diabetic kidney disease RS Farias, RP Silva-Aguiar, DE Teixeira, CP Gomes, AAS Pinheiro, ... European Journal of Pharmacology 942, 175521, 2023 | 9 | 2023 |