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I Can Kazan
I Can Kazan
在 asu.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity
KE Larrimore, IC Kazan, L Kannan, RP Kendle, T Jamal, M Barcus, ...
Scientific reports 7 (1), 10419, 2017
292017
Protein folding stability and binding interactions through the lens of evolution: a dynamical perspective
T Modi, P Campitelli, IC Kazan, SB Ozkan
Current opinion in structural biology 66, 207-215, 2021
242021
Dynamic coupling of residues within proteins as a mechanistic foundation of many enigmatic pathogenic missense variants
NJ Ose, BM Butler, A Kumar, IC Kazan, M Sanderford, S Kumar, ...
PLoS computational biology 18 (4), e1010006, 2022
112022
Coevolving residues inform protein dynamics profiles and disease susceptibility of nSNVs
BM Butler, IC Kazan, A Kumar, SB Ozkan
PLoS computational biology 14 (11), e1006626, 2018
112018
The role of rigid residues in modulating TEM-1 β-lactamase function and thermostability
B Kolbaba-Kartchner, IC Kazan, JH Mills, SB Ozkan
International journal of molecular sciences 22 (6), 2895, 2021
62021
Design of novel cyanovirin-N variants by modulation of binding dynamics through distal mutations
IC Kazan, P Sharma, MI Rahman, A Bobkov, R Fromme, G Ghirlanda, ...
Elife 11, e67474, 2022
42022
Investigating the allosteric response of the PICK1 PDZ domain to different ligands with all‐atom simulations
AO Stevens, IC Kazan, B Ozkan, Y He
Protein Science 31 (12), e4474, 2022
42022
Allosteric regulatory control in dihydrofolate reductase is revealed by dynamic asymmetry
IC Kazan, JH Mills, SB Ozkan
Protein Science 32 (8), e4700, 2023
12023
A method for the incorporation of protein dynamics into computational enzyme design using the Rosetta software suite
BK Kartchner, IC Kazan, SB Ozkan, JH Mills
Biophysical Journal 118 (3), 320a-321a, 2020
12020
Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity (vol 7 …
KE Larrimore, I Kazan, L Kannan, R Kendle, T Jamal, M Barcus, A Bolia, ...
SCIENTIFIC REPORTS 8, 2018
12018
Engineering gain‐of‐function mutants of a WW domain by dynamics and structural analysis
J Lu, MI Rahman, IC Kazan, NR Halloran, AA Bobkov, SB Ozkan, ...
Protein Science, e4759, 2023
2023
Understanding the evolution of cold sensing and menthol activation in TRPM8
N Ramesh, D Luu, KH Shah, ICJ Kazan, SB Ozkan, WD Van Horn
Biophysical journal 122 (3), 197a, 2023
2023
Allosteric regulatory control in dihydrofolate reductase (DHFR) revealed with dynamic asymmetry in unliganded ensemble
ICJ Kazan, JH Mills, SB Ozkan
Biophysical Journal 122 (3), 48a, 2023
2023
Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics
NJ Ose, PJ Campitelli, T Modi, IC Kazan, S Kumar, SB Ozkan
bioRxiv, 2023.09. 14.557827, 2023
2023
Evolutionary Guided Molecular Dynamics Driven Protein Design
IC Kazan
Arizona State University, 2023
2023
Track: Protein and Ligand-A New Marriage Between an Old Couple Functional Ancestral Reconstruction of the Cold and Menthol Sensor TRPM8
D Luu, K Shah, N Ramesh, I Kazan, SB Ozkan, W Van Horn
PROTEIN SCIENCE 32, 2023
2023
Adaptive Evolution of SARS-CoV-2: A Perspective from Dynamics
IC Kazan, SB Ozkan
Biophysical Journal 120 (3), 300a-301a, 2021
2021
Design of novel CV-N variants: Modulation of binding dynamics through distal mutations
IC Kazan, P Sharma, A Bobkov, R Fromme, G Ghirlanda, SB Ozkan
bioRxiv, 2020.12. 21.423842, 2020
2020
Plant-expressed cocaine hydrolase variants of butyrylcholinesterase and methods of reducing cocaine-primed reinstatement
T Mor, K Larrimore, IJ Kazan, S Ozkan, J Neisewander
US Patent App. 16/560,993, 2020
2020
Large Scale Disease Susceptibility Prediction of nSNVs by Dynamics Information Based Neural Networks
IC Kazan, SB Ozkan
Biophysical Journal 118 (3), 205a, 2020
2020
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