| Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells C Commisso, SM Davidson, RG Soydaner-Azeloglu, SJ Parker, ... Nature 497 (7451), 633-637, 2013 | 1637 | 2013 |
| Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I K Yamamoto, A Venida, J Yano, DE Biancur, M Kakiuchi, S Gupta, ... Nature 581 (7806), 100-105, 2020 | 806 | 2020 |
| Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells CA Lewis, SJ Parker, BP Fiske, D McCloskey, DY Gui, CR Green, ... Molecular cell 55 (2), 253-263, 2014 | 603 | 2014 |
| Reductive carboxylation supports redox homeostasis during anchorage-independent growth L Jiang, AA Shestov, P Swain, C Yang, SJ Parker, QA Wang, LS Terada, ... Nature 532 (7598), 255-258, 2016 | 596 | 2016 |
| Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models RU Svensson, SJ Parker, LJ Eichner, MJ Kolar, M Wallace, SN Brun, ... Nature medicine 22 (10), 1108-1119, 2016 | 450 | 2016 |
| Transaminase inhibition by 2-hydroxyglutarate impairs glutamate biosynthesis and redox homeostasis in glioma SK McBrayer, JR Mayers, GJ DiNatale, DD Shi, J Khanal, AA Chakraborty, ... Cell 175 (1), 101-116. e25, 2018 | 310 | 2018 |
| Regulation of substrate utilization by the mitochondrial pyruvate carrier NM Vacanti, AS Divakaruni, CR Green, SJ Parker, RR Henry, TP Ciaraldi, ... Molecular cell 56 (3), 425-435, 2014 | 299 | 2014 |
| IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism AR Grassian, SJ Parker, SM Davidson, AS Divakaruni, CR Green, ... Cancer research 74 (12), 3317-3331, 2014 | 290 | 2014 |
| Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism C Lussey-Lepoutre, KER Hollinshead, C Ludwig, M Menara, A Morin, ... Nature communications 6 (1), 8784, 2015 | 226 | 2015 |
| Metabolic consequences of oncogenic IDH mutations SJ Parker, CM Metallo Pharmacology & therapeutics 152, 54-62, 2015 | 170 | 2015 |
| KRAS4A directly regulates hexokinase 1 CR Amendola, JP Mahaffey, SJ Parker, IM Ahearn, WC Chen, M Zhou, ... Nature 576 (7787), 482-486, 2019 | 160* | 2019 |
| Distinct metabolic states can support self-renewal and lipogenesis in human pluripotent stem cells under different culture conditions H Zhang, MG Badur, AS Divakaruni, SJ Parker, C Jäger, K Hiller, ... Cell reports 16 (6), 1536-1547, 2016 | 133 | 2016 |
| Selective alanine transporter utilization creates a targetable metabolic niche in pancreatic cancer SJ Parker, CR Amendola, KER Hollinshead, Q Yu, K Yamamoto, ... Cancer discovery 10 (7), 1018-1037, 2020 | 124 | 2020 |
| Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells M Zarei, S Lal, SJ Parker, A Nevler, A Vaziri-Gohar, K Dukleska, ... Cancer research 77 (16), 4460-4471, 2017 | 104 | 2017 |
| Respiratory supercomplexes promote mitochondrial efficiency and growth in severely hypoxic pancreatic cancer KER Hollinshead, SJ Parker, VV Eapen, J Encarnacion-Rosado, A Sohn, ... Cell reports 33 (1), 2020 | 90 | 2020 |
| Oncogenic R132 IDH1 mutations limit NADPH for de novo lipogenesis through (D) 2-hydroxyglutarate production in fibrosarcoma cells MG Badur, T Muthusamy, SJ Parker, S Ma, SK McBrayer, T Cordes, ... Cell reports 25 (4), 1018-1026. e4, 2018 | 88 | 2018 |
| Largazole and its derivatives selectively inhibit ubiquitin activating enzyme (E1) D Ungermannova, SJ Parker, CG Nasveschuk, W Wang, B Quade, ... PLoS One 7 (1), e29208, 2012 | 82 | 2012 |
| Transsulfuration, minor player or crucial for cysteine homeostasis in cancer HF Zhang, RIK Geltink, SJ Parker, PH Sorensen Trends in cell biology 32 (9), 800-814, 2022 | 73 | 2022 |
| Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11 S Mukhopadhyay, DE Biancur, SJ Parker, K Yamamoto, RS Banh, ... Proceedings of the National Academy of Sciences 118 (6), e2021475118, 2021 | 66 | 2021 |
| Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma HF Zhang, CS Hughes, W Li, JZ He, D Surdez, AM El-Naggar, H Cheng, ... Cancer discovery 11 (11), 2884-2903, 2021 | 60 | 2021 |
