Structure of a flavivirus envelope glycoprotein in its low‐pH‐induced membrane fusion conformation S Bressanelli, K Stiasny, SL Allison, EA Stura, S Duquerroy, J Lescar, ... The EMBO journal 23 (4), 728-738, 2004 | 745 | 2004 |
The fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH J Lescar, A Roussel, MW Wien, J Navaza, SD Fuller, G Wengler, ... Cell 105 (1), 137-148, 2001 | 646 | 2001 |
Conventional and unconventional mechanisms for capping viral mRNA E Decroly, F Ferron, J Lescar, B Canard Nature Reviews Microbiology 10 (1), 51-65, 2012 | 505 | 2012 |
Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution TL Yap, T Xu, YL Chen, H Malet, MP Egloff, B Canard, SG Vasudevan, ... Journal of virology 81 (9), 4753-4765, 2007 | 493 | 2007 |
Ten years of dengue drug discovery: progress and prospects SP Lim, QY Wang, CG Noble, YL Chen, H Dong, B Zou, F Yokokawa, ... Antiviral research 100 (2), 500-519, 2013 | 397 | 2013 |
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-O-methyltransferase nsp10/nsp16 complex E Decroly, C Debarnot, F Ferron, M Bouvet, B Coutard, I Imbert, L Gluais, ... PLoS pathogens 7 (5), e1002059, 2011 | 368 | 2011 |
Crystal structure of the NS3 protease-helicase from dengue virus D Luo, T Xu, C Hunke, G Gruber, SG Vasudevan, J Lescar Journal of virology 82 (1), 173-183, 2008 | 360 | 2008 |
The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development D Luo, SG Vasudevan, J Lescar Antiviral research 118, 148-158, 2015 | 309 | 2015 |
Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein D Luo, T Xu, RP Watson, D Scherer‐Becker, A Sampath, W Jahnke, ... The EMBO journal 27 (23), 3209-3219, 2008 | 297 | 2008 |
The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket H Malet, B Coutard, S Jamal, H Dutartre, N Papageorgiou, M Neuvonen, ... Journal of virology 83 (13), 6534-6545, 2009 | 282 | 2009 |
Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target J Lescar, D Luo, T Xu, A Sampath, SP Lim, B Canard, SG Vasudevan Antiviral research 80 (2), 94-101, 2008 | 262 | 2008 |
Structure of the Dengue virus helicase/nucleoside triphosphatase catalytic domain at a resolution of 2.4 A T Xu, A Sampath, A Chao, D Wen, M Nanao, P Chene, SG Vasudevan, ... Journal of virology 79 (16), 10278-10288, 2005 | 259 | 2005 |
Structure of the Functional Form of the Mosquito Larvicidal Cry4Aa Toxin from Bacillus thuringiensis at a 2.8-Angstrom Resolution P Boonserm, M Mo, C Angsuthanasombat, J Lescar Journal of Bacteriology 188 (9), 3391-3401, 2006 | 258 | 2006 |
The flavivirus polymerase as a target for drug discovery H Malet, N Massé, B Selisko, JL Romette, K Alvarez, JC Guillemot, ... Antiviral research 80 (1), 23-35, 2008 | 250 | 2008 |
Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein JJH Chu, R Rajamanonmani, J Li, R Bhuvanakantham, J Lescar, ML Ng Journal of General Virology 86 (2), 405-412, 2005 | 246 | 2005 |
Structure of the NS2B-NS3 protease from Zika virus after self-cleavage WW Phoo, Y Li, Z Zhang, MY Lee, YR Loh, YB Tan, EY Ng, J Lescar, ... Nature communications 7 (1), 13410, 2016 | 224 | 2016 |
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication Y Zhao, TS Soh, J Zheng, KWK Chan, WW Phoo, CC Lee, MYF Tay, ... PLoS pathogens 11 (3), e1004682, 2015 | 221 | 2015 |
Biochemical and structural analysis of Helix pomatia agglutinin: A hexameric lectin with a novel fold JF Sanchez, J Lescar, V Chazalet, A Audfray, J Gagnon, R Alvarez, ... Journal of Biological Chemistry 281 (29), 20171-20180, 2006 | 206 | 2006 |
The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription B Morin, B Coutard, M Lelke, F Ferron, R Kerber, S Jamal, A Frangeul, ... PLoS pathogens 6 (9), e1001038, 2010 | 199 | 2010 |
Engineering a catalytically efficient recombinant protein ligase R Yang, YH Wong, GKT Nguyen, JP Tam, J Lescar, B Wu Journal of the American Chemical Society 139 (15), 5351-5358, 2017 | 195 | 2017 |