PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells JD Kahn, PG Miller, AJ Silver, RS Sellar, S Bhatt, C Gibson, M McConkey, ... Blood, The Journal of the American Society of Hematology 132 (11), 1095-1105, 2018 | 197 | 2018 |
Inhibition of USP10 induces degradation of oncogenic FLT3 EL Weisberg, NJ Schauer, J Yang, I Lamberto, L Doherty, S Bhatt, ... Nature chemical biology 13 (12), 1207-1215, 2017 | 115 | 2017 |
Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma KA Sarosiek, LE Cavallin, S Bhatt, NL Toomey, Y Natkunam, W Blasini, ... Proceedings of the National Academy of Sciences 107 (29), 13069-13074, 2010 | 105 | 2010 |
Reduced mitochondrial apoptotic priming drives resistance to BH3 mimetics in acute myeloid leukemia S Bhatt, MS Pioso, EA Olesinski, B Yilma, JA Ryan, T Mashaka, B Leutz, ... Cancer cell 38 (6), 872-890. e6, 2020 | 99 | 2020 |
miR-155 regulates HGAL expression and increases lymphoma cell motility LN Dagan, X Jiang, S Bhatt, E Cubedo, K Rajewsky, IS Lossos Blood, The Journal of the American Society of Hematology 119 (2), 513-520, 2012 | 93 | 2012 |
Statins enhance efficacy of venetoclax in blood cancers JS Lee, A Roberts, D Juarez, TTT Vo, S Bhatt, L Herzog, S Mallya, ... Science translational medicine 10 (445), eaaq1240, 2018 | 88 | 2018 |
CD30 targeting with brentuximab vedotin: a novel therapeutic approach to primary effusion lymphoma S Bhatt, BM Ashlock, Y Natkunam, V Sujoy, JR Chapman, JC Ramos, ... Blood, The Journal of the American Society of Hematology 122 (7), 1233-1242, 2013 | 88 | 2013 |
Efficacious proteasome/HDAC inhibitor combination therapy for primary effusion lymphoma S Bhatt, BM Ashlock, NL Toomey, LA Diaz, EA Mesri, IS Lossos, ... The Journal of clinical investigation 123 (6), 2616-2628, 2013 | 76 | 2013 |
Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs AS Sperling, M Burgess, H Keshishian, JA Gasser, S Bhatt, M Jan, ... Blood, The Journal of the American Society of Hematology 134 (2), 160-170, 2019 | 62 | 2019 |
miR-181a negatively regulates NF-κB signaling and affects activated B-cell–like diffuse large B-cell lymphoma pathogenesis GA Kozloski, X Jiang, S Bhatt, J Ruiz, F Vega, R Shaknovich, A Melnick, ... Blood, The Journal of the American Society of Hematology 127 (23), 2856-2866, 2016 | 58 | 2016 |
Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma E Cubedo, AJ Gentles, C Huang, Y Natkunam, S Bhatt, X Lu, X Jiang, ... Blood, The Journal of the American Society of Hematology 119 (23), 5478-5491, 2012 | 50 | 2012 |
Direct and immune-mediated cytotoxicity of interleukin-21 contributes to antitumor effects in mantle cell lymphoma S Bhatt, J Matthews, S Parvin, KA Sarosiek, D Zhao, X Jiang, E Isik, ... Blood, The Journal of the American Society of Hematology 126 (13), 1555-1564, 2015 | 38 | 2015 |
Anti-CD20-interleukin-21 fusokine targets malignant B cells via direct apoptosis and NK-cell–dependent cytotoxicity S Bhatt, S Parvin, Y Zhang, HM Cho, K Kunkalla, F Vega, JM Timmerman, ... Blood, The Journal of the American Society of Hematology 129 (16), 2246-2256, 2017 | 31 | 2017 |
Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma JM Matthews, S Bhatt, MP Patricelli, TK Nomanbhoy, X Jiang, ... Blood, The Journal of the American Society of Hematology 128 (2), 239-248, 2016 | 25 | 2016 |
Chlamydophila psittaci-negative ocular adnexal marginal zone lymphomas express self polyreactive B-cell receptors D Zhu, S Bhatt, X Lu, F Guo, H Veelken, DK Hsu, FT Liu, S Alvarez Cubela, ... Leukemia 29 (7), 1587-1599, 2015 | 23 | 2015 |
Interleukin 21–its potential role in the therapy of B-cell lymphomas S Bhatt, KA Sarosiek, IS Lossos Leukemia & lymphoma 58 (1), 17-29, 2017 | 22 | 2017 |
Increased mitochondrial apoptotic priming with targeted therapy predicts clinical response to re‐induction chemotherapy JS Garcia, S Bhatt, G Fell, AS Sperling, M Burgess, H Keshishian, B Yilma, ... American journal of hematology 95 (3), 245-250, 2020 | 16 | 2020 |
Suramin, penciclovir, and anidulafungin exhibit potential in the treatment of COVID-19 via binding to nsp12 of SARS-CoV-2 SK Dey, M Saini, C Dhembla, S Bhatt, AS Rajesh, V Anand, HK Das, ... Journal of Biomolecular Structure and Dynamics 40 (24), 14067-14083, 2022 | 15 | 2022 |
Combination therapy targeting Erk1/2 and CDK4/6i in relapsed refractory multiple myeloma S Adamia, S Bhatt, K Wen, Z Chyra, GG Fell, YT Tai, MS Pioso, I Abiatari, ... Leukemia 36 (4), 1088-1101, 2022 | 12 | 2022 |
PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy PG Miller, AS Sperling, C Mayerhofer, ME McConkey, JM Ellegast, ... Blood 142 (24), 2079-2091, 2023 | 10 | 2023 |