Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences IA Leclercq, ADS Morais, B Schroyen, N Van Hul, A Geerts Journal of hepatology 47 (1), 142-156, 2007 | 491 | 2007 |
Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice R Español–Suñer, R Carpentier, N Van Hul, V Legry, Y Achouri, S Cordi, ... Gastroenterology 143 (6), 1564-1575. e7, 2012 | 396 | 2012 |
Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells R Carpentier, RE Suñer, N Van Hul, JL Kopp, JB Beaudry, S Cordi, ... Gastroenterology 141 (4), 1432-1438. e4, 2011 | 293 | 2011 |
Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE‐induced murine model of chronic liver injury NKM Van Hul, J Abarca‐Quinones, C Sempoux, Y Horsmans, IA Leclercq Hepatology 49 (5), 1625-1635, 2009 | 201 | 2009 |
Spatial Transcriptomics to define transcriptional patterns of zonation and structural components in the mouse liver F Hildebrandt, A Andersson, S Saarenpää, L Larsson, N Van Hul, ... Nature communications 12 (1), 7046, 2021 | 117 | 2021 |
Metabolic remodeling during liver regeneration MJ Caldez, N Van Hul, HWL Koh, XQ Teo, JJ Fan, PY Tan, MR Dewhurst, ... Developmental cell 47 (4), 425-438. e5, 2018 | 95 | 2018 |
Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury N Van Hul, N Lanthier, RE Suñer, JA Quinones, N van Rooijen, I Leclercq The American journal of pathology 179 (4), 1839-1850, 2011 | 93 | 2011 |
Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality R Szmyd, J Niska-Blakie, MK Diril, P Renck Nunes, K Tzelepis, A Lacroix, ... Oncogene 38 (7), 998-1018, 2019 | 65 | 2019 |
Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin IA Leclercq, M Vansteenberghe, VB Lebrun, NK VanHul, ... Laboratory investigation 86 (11), 1161-1171, 2006 | 58 | 2006 |
Distribution of human β-defensin polymorphisms in various control and cystic fibrosis populations A Vankeerberghen, O Scudiero, K De Boeck, M Macek Jr, PF Pignatti, ... Genomics 85 (5), 574-581, 2005 | 41 | 2005 |
Loss of hepatocyte cell division leads to liver inflammation and fibrosis MR Dewhurst, JR Ow, G Zafer, NKM van Hul, H Wollmann, X Bisteau, ... PLoS genetics 16 (11), e1009084, 2020 | 37 | 2020 |
Biomimetic niches reveal the minimal cues to trigger apical lumen formation in single hepatocytes Y Zhang, R De Mets, C Monzel, V Acharya, P Toh, JFL Chin, N Van Hul, ... Nature Materials 19 (9), 1026-1035, 2020 | 37 | 2020 |
Protective functions of ZO-2/Tjp2 expressed in hepatocytes and cholangiocytes against liver injury and cholestasis J Xu, PJ Kausalya, N Van Hul, MJ Caldez, S Xu, AGM Ong, WL Woo, ... Gastroenterology 160 (6), 2103-2118, 2021 | 36 | 2021 |
Macrophage depletion attenuates extracellular matrix deposition and ductular reaction in a mouse model of chronic cholangiopathies J Best, S Verhulst, WK Syn, K Lagaisse, N van Hul, F Heindryckx, ... Plos one 11 (9), e0162286, 2016 | 35 | 2016 |
CDK10 mutations in humans and mice cause severe growth retardation, spine malformations, and developmental delays C Windpassinger, J Piard, C Bonnard, M Alfadhel, S Lim, X Bisteau, ... The American Journal of Human Genetics 101 (3), 391-403, 2017 | 34 | 2017 |
Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation SE Minnis-Lyons, S Ferreira-González, N Aleksieva, TY Man, VL Gadd, ... Science Signaling 14 (688), eaay9185, 2021 | 29 | 2021 |
Invasive ductular reaction operates hepatobiliary junctions upon hepatocellular injury in rodents and humans LA Clerbaux, R Manco, N Van Hul, C Bouzin, A Sciarra, C Sempoux, ... The American journal of pathology 189 (8), 1569-1581, 2019 | 29 | 2019 |
Participation of liver progenitor cells in liver regeneration: lack of evidence in the AAF/PH rat model AC Dusabineza, NK Van Hul, J Abarca-Quinones, P Starkel, M Najimi, ... Laboratory investigation 92 (1), 72-81, 2012 | 27 | 2012 |
DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome S Hankeova, J Salplachta, T Zikmund, M Kavkova, N Van Hul, A Brinek, ... Elife 10, e60916, 2021 | 23 | 2021 |
IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis B Czepukojc, A Abuhaliema, A Barghash, S Tierling, N Naß, Y Simon, ... Frontiers in medicine 6, 179, 2019 | 20 | 2019 |