The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors M Mahameed, T Wilhelm, O Darawshi, A Obiedat, WS Tommy, C Chintha, ... Cell death & disease 10 (4), 300, 2019 | 82 | 2019 |
Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway J Zhang, CM Simpson, J Berner, HB Chong, J Fang, Z Ordulu, ... Cell 186 (11), 2361-2379. e25, 2023 | 67 | 2023 |
Characterizing cathepsin activity and macrophage subtypes in excised human carotid plaques I Abd-Elrahman, K Meir, H Kosuge, Y Ben-Nun, T Weiss Sadan, ... Stroke 47 (4), 1101-1108, 2016 | 66 | 2016 |
NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer T Weiss-Sadan, M Ge, M Hayashi, M Gohar, CH Yao, A de Groot, S Harry, ... Cell metabolism 35 (3), 487-503. e7, 2023 | 61 | 2023 |
CT imaging of enzymatic activity in cancer using covalent probes reveal a size-dependent pattern D Tsvirkun, Y Ben-Nun, E Merquiol, I Zlotver, K Meir, T Weiss-Sadan, ... Journal of the American Chemical Society 140 (38), 12010-12020, 2018 | 61 | 2018 |
A novel quenched fluorescent activity-based probe reveals caspase-3 activity in the endoplasmic reticulum during apoptosis Y Shaulov-Rotem, E Merquiol, T Weiss-Sadan, O Moshel, S Salpeter, ... Chemical Science 7 (2), 1322-1337, 2016 | 50 | 2016 |
Cysteine proteases in atherosclerosis T Weiss‐Sadan, I Gotsman, G Blum The FEBS Journal 284 (10), 1455-1472, 2017 | 45 | 2017 |
Cathepsin activity-based probes and inhibitor for preclinical atherosclerosis imaging and macrophage depletion I Abd-Elrahman, H Kosuge, T Wises Sadan, Y Ben-Nun, K Meir, ... PLoS One 11 (8), e0160522, 2016 | 41 | 2016 |
Cathepsin inhibition modulates metabolism and polarization of tumor-associated macrophages D Oelschlaegel, T Weiss Sadan, S Salpeter, S Krug, G Blum, W Schmitz, ... Cancers 12 (9), 2579, 2020 | 39 | 2020 |
Relative genomic stability of adipose tissue derived mesenchymal stem cells: analysis of ploidy, H19 long non-coding RNA and p53 activity O Ravid, O Shoshani, M Sela, A Weinstock, TW Sadan, E Gur, D Zipori, ... Stem cell research & therapy 5, 1-11, 2014 | 31 | 2014 |
A theranostic cathepsin activity-based probe for noninvasive intervention in cardiovascular diseases T Weiss-Sadan, Y Ben-Nun, D Maimoun, E Merquiol, I Abd-Elrahman, ... Theranostics 9 (20), 5731, 2019 | 26 | 2019 |
Cathepsins drive anti-inflammatory activity by regulating autophagy and mitochondrial dynamics in macrophage foam cells T Weiss-Sadan, D Maimoun, D Oelschlagel, F Kaschani, D Misiak, ... Cell Physiol Biochem 53 (3), 550-72, 2019 | 25 | 2019 |
Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation [S] T Weiss-Sadan, G Itzhak, F Kaschani, Z Yu, M Mahameed, A Anaki, ... Molecular & Cellular Proteomics 18 (7), 1330-1344, 2019 | 9 | 2019 |
Improved Cathepsin Probes for Sensitive Molecular Imaging Y Yitzhak, H Gaikwad, T Weiss-Sadan, E Merquiol, B Turk, G Blum Molecules 27 (3), 842, 2022 | 2 | 2022 |
Cysteine Proteases Cathepsins: From Basic Science to Translational Applications T Weiss-Sadan PQDT-Global, 2019 | | 2019 |