ATM is down-regulated by N-Myc–regulated microRNA-421 H Hu, L Du, G Nagabayashi, RC Seeger, RA Gatti Proceedings of the National Academy of Sciences 107 (4), 1506-1511, 2010 | 310 | 2010 |
MicroRNAs: new players in the DNA damage response H Hu, RA Gatti Journal of molecular cell biology 3 (3), 151-158, 2011 | 212 | 2011 |
Nonaminoglycoside compounds induce readthrough of nonsense mutations L Du, R Damoiseaux, S Nahas, K Gao, H Hu, JM Pollard, J Goldstine, ... The Journal of experimental medicine 206 (10), 2285, 2009 | 168 | 2009 |
Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum L Du, R Kayali, C Bertoni, F Fike, H Hu, PL Iversen, RA Gatti Human molecular genetics 20 (16), 3151-3160, 2011 | 155 | 2011 |
RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration H Hu, JM Bliss, Y Wang, J Colicelli Current Biology 15 (9), 815-823, 2005 | 150 | 2005 |
MYC-induced reprogramming of glutamine catabolism supports optimal virus replication M Thai, SK Thaker, J Feng, Y Du, H Hu, T Ting Wu, TG Graeber, D Braas, ... Nature communications 6 (1), 8873, 2015 | 143 | 2015 |
The RAS effector RIN1 modulates the formation of aversive memories A Dhaka, RM Costa, H Hu, DK Irvin, A Patel, HI Kornblum, AJ Silva, ... Journal of Neuroscience 23 (3), 748-757, 2003 | 94 | 2003 |
N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ATM pathway Y Yin, L Xu, Y Chang, T Zeng, X Chen, A Wang, J Groth, WC Foo, C Liang, ... Molecular cancer 18, 1-13, 2019 | 91 | 2019 |
Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer Y Li, Y He, W Butler, L Xu, Y Chang, K Lei, H Zhang, Y Zhou, AC Gao, ... Science translational medicine 11 (521), eaax0428, 2019 | 84 | 2019 |
Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma WY Mansour, NV Bogdanova, U Kasten-Pisula, T Rieckmann, S Köcher, ... Radiotherapy and oncology 106 (1), 147-154, 2013 | 81 | 2013 |
A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene L Du, ME Jung, R Damoiseaux, G Completo, F Fike, JM Ku, S Nahas, ... Molecular Therapy 21 (9), 1653-1660, 2013 | 77 | 2013 |
RIN1 is a breast tumor suppressor gene M Milstein, CK Mooser, H Hu, M Fejzo, D Slamon, L Goodglick, S Dry, ... Cancer research 67 (24), 11510-11516, 2007 | 69 | 2007 |
Integration of transforming growth factor β and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration H Hu, M Milstein, JM Bliss, M Thai, G Malhotra, LC Huynh, J Colicelli Molecular and cellular biology, 2008 | 67 | 2008 |
A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer L Xu, Y Yin, Y Li, X Chen, Y Chang, H Zhang, J Liu, J Beasley, P McCaw, ... Proceedings of the National Academy of Sciences 118 (13), e2012748118, 2021 | 62 | 2021 |
Synthesis and evaluation of compounds that induce readthrough of premature termination codons ME Jung, JM Ku, L Du, H Hu, RA Gatti Bioorganic & medicinal chemistry letters 21 (19), 5842-5848, 2011 | 57 | 2011 |
ATM–dependent miR-335 targets CtIP and modulates the DNA damage response NT Martin, K Nakamura, R Davies, SA Nahas, C Brown, R Tunuguntla, ... PLoS genetics 9 (5), e1003505, 2013 | 55 | 2013 |
Inactivation of the nod box distal half‐site allows tetrameric NodD to activate nodA transcription in an inducer‐independent manner J Feng, Q Li, HL Hu, XC Chen, GF Hong Nucleic acids research 31 (12), 3143-3156, 2003 | 47 | 2003 |
Defective DNA double‐strand break repair in pediatric systemic lupus erythematosus RC Davies, K Pettijohn, F Fike, J Wang, SA Nahas, R Tunuguntla, H Hu, ... Arthritis & Rheumatism 64 (2), 568-578, 2012 | 46 | 2012 |
Circulating tumor cells (CTCs): a unique model of cancer metastases and non-invasive biomarkers of therapeutic response J Liu, J Lian, Y Chen, X Zhao, CZ Du, Y Xu, H Hu, H Rao, X Hong Frontiers in Genetics 12, 734595, 2021 | 44 | 2021 |
SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs P Lee, NT Martin, K Nakamura, S Azghadi, M Amiri, U Ben-David, ... Nature communications 4 (1), 1824, 2013 | 42 | 2013 |