A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication K Ratia, S Pegan, J Takayama, K Sleeman, M Coughlin, S Baliji, ... Proceedings of the National Academy of Sciences 105 (42), 16119-16124, 2008 | 496 | 2008 |
Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise-regulated kinases and AMPK substrates NJ Hoffman, BL Parker, R Chaudhuri, KH Fisher-Wellman, M Kleinert, ... Cell metabolism 22 (5), 922-935, 2015 | 402 | 2015 |
Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein− ligand X-ray structure and biological evaluation AK Ghosh, J Takayama, KV Rao, K Ratia, R Chaudhuri, DC Mulhearn, ... Journal of medicinal chemistry 53 (13), 4968-4979, 2010 | 168 | 2010 |
Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans KT Tonks, ACF Coster, MJ Christopher, R Chaudhuri, A Xu, ... Obesity 24 (4), 908-916, 2016 | 165 | 2016 |
Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome− coronavirus papain-like … AK Ghosh, J Takayama, Y Aubin, K Ratia, R Chaudhuri, Y Baez, ... Journal of medicinal chemistry 52 (16), 5228-5240, 2009 | 141 | 2009 |
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance DJ Fazakerley, R Chaudhuri, P Yang, GJ Maghzal, KC Thomas, JR Krycer, ... Elife 7, e32111, 2018 | 117 | 2018 |
Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry BL Parker, G Yang, SJ Humphrey, R Chaudhuri, X Ma, S Peterman, ... Science signaling 8 (380), rs6-rs6, 2015 | 74 | 2015 |
Global phosphoproteomic mapping of early mitotic exit in human cells identifies novel substrate dephosphorylation motifs RA McCloy, BL Parker, S Rogers, R Chaudhuri, V Gayevskiy, NJ Hoffman, ... Molecular & Cellular Proteomics 14 (8), 2194-2212, 2015 | 69 | 2015 |
mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3 M Kleinert, BL Parker, R Chaudhuri, DJ Fazakerley, A Serup, KC Thomas, ... Molecular metabolism 5 (8), 646-655, 2016 | 64 | 2016 |
Kinome screen identifies PFKFB3 and glucose metabolism as important regulators of the insulin/insulin-like growth factor (IGF)-1 signaling pathway S Trefely, PS Khoo, JR Krycer, R Chaudhuri, DJ Fazakerley, BL Parker, ... Journal of Biological Chemistry 290 (43), 25834-25846, 2015 | 64 | 2015 |
Proteomic analysis of GLUT4 storage vesicles reveals tumor suppressor candidate 5 (TUSC5) as a novel regulator of insulin action in adipocytes DJ Fazakerley, S Naghiloo, R Chaudhuri, F Koumanov, JG Burchfield, ... Journal of Biological Chemistry 290 (39), 23528-23542, 2015 | 61 | 2015 |
Phosphoproteomics reveals conserved exercise‐stimulated signaling and AMPK regulation of store‐operated calcium entry ME Nelson, BL Parker, JG Burchfield, NJ Hoffman, EJ Needham, ... The EMBO journal 38 (24), e102578, 2019 | 53 | 2019 |
Reducing agents affect inhibitory activities of compounds: results from multiple drug targets H Lee, J Torres, L Truong, R Chaudhuri, A Mittal, ME Johnson Analytical biochemistry 423 (1), 46-53, 2012 | 47 | 2012 |
DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake J Li, J Cantley, JG Burchfield, CC Meoli, J Stöckli, PT Whitworth, H Pant, ... Diabetologia 57, 2173-2182, 2014 | 46 | 2014 |
Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass JR Davey, KI Watt, BL Parker, R Chaudhuri, JG Ryall, L Cunningham, ... JCI insight 1 (5), 2016 | 41 | 2016 |
Skeletal muscle extracellular matrix remodeling after short-term overfeeding in healthy humans CS Tam, R Chaudhuri, AT Hutchison, D Samocha-Bonet, LK Heilbronn Metabolism 67, 26-30, 2017 | 40 | 2017 |
Metabolomic analysis of insulin resistance across different mouse strains and diets J Stöckli, KH Fisher-Wellman, R Chaudhuri, XY Zeng, DJ Fazakerley, ... Journal of Biological Chemistry 292 (47), 19135-19145, 2017 | 38 | 2017 |
Comparison of SARS and NL63 papain-like protease binding sites and binding site dynamics: inhibitor design implications R Chaudhuri, S Tang, G Zhao, H Lu, DA Case, ME Johnson Journal of molecular biology 414 (2), 272-288, 2011 | 36 | 2011 |
PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications R Chaudhuri, A Sadrieh, NJ Hoffman, BL Parker, SJ Humphrey, J Stöckli, ... BMC genomics 16, 1-14, 2015 | 24 | 2015 |
Synergistic Inhibitor Binding to the Papain‐Like Protease of Human SARS Coronavirus: Mechanistic and Inhibitor Design Implications H Lee, S Cao, KE Hevener, L Truong, JL Gatuz, K Patel, AK Ghosh, ... ChemMedChem 8 (8), 1361-1372, 2013 | 24 | 2013 |