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Rima Chaudhuri
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A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication
K Ratia, S Pegan, J Takayama, K Sleeman, M Coughlin, S Baliji, ...
Proceedings of the National Academy of Sciences 105 (42), 16119-16124, 2008
4962008
Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise-regulated kinases and AMPK substrates
NJ Hoffman, BL Parker, R Chaudhuri, KH Fisher-Wellman, M Kleinert, ...
Cell metabolism 22 (5), 922-935, 2015
4022015
Severe acute respiratory syndrome coronavirus papain-like novel protease inhibitors: design, synthesis, protein− ligand X-ray structure and biological evaluation
AK Ghosh, J Takayama, KV Rao, K Ratia, R Chaudhuri, DC Mulhearn, ...
Journal of medicinal chemistry 53 (13), 4968-4979, 2010
1682010
Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans
KT Tonks, ACF Coster, MJ Christopher, R Chaudhuri, A Xu, ...
Obesity 24 (4), 908-916, 2016
1652016
Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome− coronavirus papain-like …
AK Ghosh, J Takayama, Y Aubin, K Ratia, R Chaudhuri, Y Baez, ...
Journal of medicinal chemistry 52 (16), 5228-5240, 2009
1412009
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
DJ Fazakerley, R Chaudhuri, P Yang, GJ Maghzal, KC Thomas, JR Krycer, ...
Elife 7, e32111, 2018
1172018
Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry
BL Parker, G Yang, SJ Humphrey, R Chaudhuri, X Ma, S Peterman, ...
Science signaling 8 (380), rs6-rs6, 2015
742015
Global phosphoproteomic mapping of early mitotic exit in human cells identifies novel substrate dephosphorylation motifs
RA McCloy, BL Parker, S Rogers, R Chaudhuri, V Gayevskiy, NJ Hoffman, ...
Molecular & Cellular Proteomics 14 (8), 2194-2212, 2015
692015
mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3
M Kleinert, BL Parker, R Chaudhuri, DJ Fazakerley, A Serup, KC Thomas, ...
Molecular metabolism 5 (8), 646-655, 2016
642016
Kinome screen identifies PFKFB3 and glucose metabolism as important regulators of the insulin/insulin-like growth factor (IGF)-1 signaling pathway
S Trefely, PS Khoo, JR Krycer, R Chaudhuri, DJ Fazakerley, BL Parker, ...
Journal of Biological Chemistry 290 (43), 25834-25846, 2015
642015
Proteomic analysis of GLUT4 storage vesicles reveals tumor suppressor candidate 5 (TUSC5) as a novel regulator of insulin action in adipocytes
DJ Fazakerley, S Naghiloo, R Chaudhuri, F Koumanov, JG Burchfield, ...
Journal of Biological Chemistry 290 (39), 23528-23542, 2015
612015
Phosphoproteomics reveals conserved exercise‐stimulated signaling and AMPK regulation of store‐operated calcium entry
ME Nelson, BL Parker, JG Burchfield, NJ Hoffman, EJ Needham, ...
The EMBO journal 38 (24), e102578, 2019
532019
Reducing agents affect inhibitory activities of compounds: results from multiple drug targets
H Lee, J Torres, L Truong, R Chaudhuri, A Mittal, ME Johnson
Analytical biochemistry 423 (1), 46-53, 2012
472012
DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake
J Li, J Cantley, JG Burchfield, CC Meoli, J Stöckli, PT Whitworth, H Pant, ...
Diabetologia 57, 2173-2182, 2014
462014
Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass
JR Davey, KI Watt, BL Parker, R Chaudhuri, JG Ryall, L Cunningham, ...
JCI insight 1 (5), 2016
412016
Skeletal muscle extracellular matrix remodeling after short-term overfeeding in healthy humans
CS Tam, R Chaudhuri, AT Hutchison, D Samocha-Bonet, LK Heilbronn
Metabolism 67, 26-30, 2017
402017
Metabolomic analysis of insulin resistance across different mouse strains and diets
J Stöckli, KH Fisher-Wellman, R Chaudhuri, XY Zeng, DJ Fazakerley, ...
Journal of Biological Chemistry 292 (47), 19135-19145, 2017
382017
Comparison of SARS and NL63 papain-like protease binding sites and binding site dynamics: inhibitor design implications
R Chaudhuri, S Tang, G Zhao, H Lu, DA Case, ME Johnson
Journal of molecular biology 414 (2), 272-288, 2011
362011
PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications
R Chaudhuri, A Sadrieh, NJ Hoffman, BL Parker, SJ Humphrey, J Stöckli, ...
BMC genomics 16, 1-14, 2015
242015
Synergistic Inhibitor Binding to the Papain‐Like Protease of Human SARS Coronavirus: Mechanistic and Inhibitor Design Implications
H Lee, S Cao, KE Hevener, L Truong, JL Gatuz, K Patel, AK Ghosh, ...
ChemMedChem 8 (8), 1361-1372, 2013
242013
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