| Identification of recurrent SMO and BRAF mutations in ameloblastomas RT Sweeney, AC McClary, BR Myers, J Biscocho, L Neahring, KA Kwei, ... Nature genetics 46 (7), 722-725, 2014 | 364 | 2014 |
| Structural basis for cholesterol transport-like activity of the hedgehog receptor patched Y Zhang, DP Bulkley, Y Xin, KJ Roberts, DE Asarnow, A Sharma, ... Cell 175 (5), 1352-1364. e14, 2018 | 222 | 2018 |
| Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function DA Prober, S Zimmerman, BR Myers, BM McDermott, SH Kim, S Caron, ... Journal of Neuroscience 28 (40), 10102-10110, 2008 | 211 | 2008 |
| Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response BR Myers, N Sever, YC Chong, J Kim, JD Belani, S Rychnovsky, ... Developmental cell 26 (4), 346-357, 2013 | 202 | 2013 |
| Smoothened stimulation by membrane sterols drives Hedgehog pathway activity I Deshpande, J Liang, D Hedeen, KJ Roberts, Y Zhang, B Ha, ... Nature 571 (7764), 284-288, 2019 | 183 | 2019 |
| A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating BR Myers, CJ Bohlen, D Julius Neuron 58 (3), 362-373, 2008 | 145 | 2008 |
| Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium BR Myers, L Neahring, Y Zhang, KJ Roberts, PA Beachy Proceedings of the National Academy of Sciences 114 (52), E11141-E11150, 2017 | 131 | 2017 |
| Evolution of thermal response properties in a cold-activated TRP channel BR Myers, YM Sigal, D Julius PloS one 4 (5), e5741, 2009 | 102 | 2009 |
| Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits CD Arveseth, JT Happ, DS Hedeen, JF Zhu, JL Capener, D Klatt Shaw, ... PLoS biology 19 (4), e3001191, 2021 | 51 | 2021 |
| Multiple unbiased prospective screens identify TRP channels and their conserved gating elements BR Myers, Y Saimi, D Julius, C Kung The Journal of general physiology 132 (5), 481-486, 2008 | 37 | 2008 |
| A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction JT Happ, CD Arveseth, J Bruystens, D Bertinetti, IB Nelson, C Olivieri, ... Nature structural & molecular biology 29 (10), 990-999, 2022 | 33 | 2022 |
| TRP channel structural biology: new roles for an old fold BR Myers, D Julius Neuron 54 (6), 847-850, 2007 | 17 | 2007 |
| Emerging mechanistic understanding of cilia function in cellular signalling KI Hilgendorf, BR Myers, JF Reiter Nature Reviews Molecular Cell Biology, 1-19, 2024 | 10 | 2024 |
| GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade MF Walker, J Zhang, W Steiner, PI Ku, JF Zhu, Z Michaelson, YC Yen, ... bioRxiv, 2023.05. 10.540226, 2023 | 2 | 2023 |
| A Ciliary SMOOTHENED-GRK2-PKA Signaling Pathway Initiates Hedgehog Signal Transduction. MF Walker, J Zhang, W Steiner, PI Ku, JF Zhu, Z Michaelson, YC Yen, ... Biorxiv: the Preprint Server for Biology, 2023 | 1 | 2023 |
| A simple and scalable zebrafish model of Sonic hedgehog medulloblastoma MJ Casey, PP Chan, Q Li, JF Zu, CA Jette, M Kohler, BR Myers, ... Cell Reports 43 (8), 2024 | | 2024 |
| GRK2 Kinases in the Primary Cilium Initiate SMOOTHENED-PKA Signaling in the Hedgehog Cascade B Myers, M Walker, J Zhang, W Steiner, P Ku, JF Zhu, Z Michaelson, ... Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024 | | 2024 |
| Abstract 1413 GRK2 Kinases in the Primary Cilium Initiate SMOOTHENED-PKA Signaling in the Hedgehog Cascade B Myers Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
| Studies of SMOOTHENED Activation in Cell-Free and Reconstituted Systems IB Nelson, BR Myers Hedgehog Signaling: Methods and Protocols, 161-174, 2022 | | 2022 |
| Rapid, Direct SMOOTHENED Activity Assays in Live Cells Using cAMP-Based Conformational Sensors MF Walker, BR Myers Hedgehog Signaling: Methods and Protocols, 175-184, 2022 | | 2022 |
